Pemetrexed EP Impurity E

SZ CAT No:	SZ-P014006
CAS No	182009-04-7
Mol.F.	C20H21N5O6
Mol.Wt.	427.4
Inv. Status	In Stock
Rel. CAS No	937370-10-0 (Disodium salt)

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Chemical Name: (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP)

Synonym: Pemetrexed R-Isomer

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(O)[C@H](NC(C1=CC=C(CCC2=CNC(NC(N)=N3)=C2C3=O)C=C1)=O)CCC(O)=O

A stability-indicating LC-MS/MS method optimization for Pemetrexed through design of experiments: Identification and characterization of major oxidative degradation product
By Narenderan, S. T.; Ramesh, J.; Babu, B.; Meyyanathan, S. N.
From Journal of Pharmaceutical and Biomedical Analysis (2020), 183, 113150

A new validated stability-indicating gradient RP-HPLC method for the determination of pemetrexed disodium and its process related substances
By Hemchand, S.; Babu, R. Ravi Chandra; Annapurna, Mukthinuthalapati Mathrusri
From Journal of Drug Delivery and Therapeutics (2019), 9(3Suppl.), 588-610

Content determination of related impurity-L-isomer in Pemetrexed Disodium for injection by HPLC
By Li, Jinhua; Yang, Mei
From Heilongjiang Yiyao (2014), 27(3), 498-500

Pemetrexed EP Impurity E is chemically (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP). It is also known as Pemetrexed R-Isomer. Pemetrexed EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Pemetrexed EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pemetrexed.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Pemetrexed EP Impurity E

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SZ CAT No:	: SZ-P014007
CAS No	: 193281-00-4
Mol.F.	: C20H21N5O7
Mol.Wt.	: 443.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014009
CAS No	: NA
Mol.F.	: C26H30N6O9
Mol.Wt.	: 570.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014006
CAS No	: 182009-04-7
Mol.F.	: C20H21N5O6
Mol.Wt.	: 427.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014005
CAS No	: 144051-68-3
Mol.F.	: C25H28N6O9
Mol.Wt.	: 556.5
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-P014010
CAS No	: 1265908-64-2
Mol.F.	: C21H23N5O6
Mol.Wt.	: 441.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014012
CAS No	: 1265908-63-1
Mol.F.	: C21H23N5O6
Mol.Wt.	: 441.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014001
CAS No	: 150399-23-8
Mol.F.	: C20H21N5O6 : 2Na
Mol.Wt.	: 427.4 : 2(23.0)
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014002
CAS No	: 869791-42-4
Mol.F.	: C21H23N5O6
Mol.Wt.	: 441.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014003
CAS No	: 1802552-04-0
Mol.F.	: C40H40N10O13
Mol.Wt.	: 868.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014004
CAS No	: 1802552-16-4
Mol.F.	: C40H40N10O13
Mol.Wt.	: 868.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014013
CAS No	: 155405-81-5
Mol.F.	: C22H25N5O6
Mol.Wt.	: 455.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014014
CAS No	: 193281-05-9
Mol.F.	: C19H21N5O7
Mol.Wt.	: 431.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014015
CAS No	: NA
Mol.F.	: C25H28N6O9
Mol.Wt.	: 556.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014016
CAS No	: 1644286-34-9
Mol.F.	: C40H40N10O13
Mol.Wt.	: 868.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014008
CAS No	: 193265-47-3
Mol.F.	: C15H14N4O4
Mol.Wt.	: 314.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014017
CAS No	: 1644286-36-1
Mol.F.	: C20H21N5O8
Mol.Wt.	: 459.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014018
CAS No	: 1644286-35-0
Mol.F.	: C20H21N5O8
Mol.Wt.	: 459.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014019
CAS No	: NA
Mol.F.	: C43H46N10O15
Mol.Wt.	: 942.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014020
CAS No	: NA
Mol.F.	: C30H38N6O9
Mol.Wt.	: 626.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014021
CAS No	: NA
Mol.F.	: C20H23N5O8
Mol.Wt.	: 461.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014022
CAS No	: NA
Mol.F.	: C20H22N4O7
Mol.Wt.	: 430.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014D01
CAS No	: 1129408-57-6
Mol.F.	: C20H16D5N5O6
Mol.Wt.	: 432.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014023
CAS No	: 2518419-18-4
Mol.F.	: C24H30N6O8
Mol.Wt.	: 530.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014024
CAS No	: NA
Mol.F.	: C20H21N5O7
Mol.Wt.	: 443.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014025
CAS No	: NA
Mol.F.	: C20H21N5O8
Mol.Wt.	: 459.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014026
CAS No	: 137281-39-1
Mol.F.	: C15H14N4O3
Mol.Wt.	: 298.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-P014011
CAS No	: 155405-80-4
Mol.F.	: C16H16N4O3
Mol.Wt.	: 312.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014027
CAS No	: NA
Mol.F.	: C21H25N5O8
Mol.Wt.	: 475.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014028
CAS No	: 1417656-72-4
Mol.F.	: C20H23N5O9
Mol.Wt.	: 477.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P014029
CAS No	: 137281-23-3
Mol.F.	: C20H21N5O6
Mol.Wt.	: 427.4
Inv. Status	: Custom Synthesis