Pazopanib Impurity 24

SZ CAT No:	SZ-P013037
CAS No	22536-67-0
Mol.F.	C4H2Cl2N2
Mol.Wt.	149.0
Inv. Status	Custom Synthesis

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: 2,5-Dichloropyrimidine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=CN=C(Cl)N=C1

Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S Kord
J Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.

Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu
Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102

Characterization of forced degradation products of pazopanib hydrochloride by UHPLC‐Q‐TOF/MS and in silico toxicity prediction
Prinesh N. Patel Pradipbhai D. Kalariya Mahesh Sharma Prabha Garg M. V. N Kumar Talluri S. Gananadhamu R. Srinivas
Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928

Development and validation of a stability indicating RP-HPLC method for the determination of Pazopanib in bulk drug and its pharmaceutical dosage form
Kishore Kumar Reddy Y, J. Raveendra Reddy and N. Devanna
J. Chem. Pharm. Res., 2015, 7(9):127-132

Validated RP-HPLC Method Development of Pazopanib in Bulk and its Pharmaceutical Dosage Form
Kiran Kumar Buralla, and Varadarajan Parthasarathy
Pharmaceutical Methods,2020,11,1,21-24.

Pazopanib Impurity 24 is chemically 2,5-Dichloropyrimidine. Pazopanib Impurity 24 is supplied with detailed characterization data compliant with regulatory guideline. Pazopanib Impurity 24 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pazopanib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Pazopanib Impurity 24

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Mol.Wt.	: 437.5
Inv. Status	: In Stock

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Mol.F.	: C4H3ClN2O
Mol.Wt.	: 130.5
Inv. Status	: Custom Synthesis

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Mol.F.	: C26H23ClN10
Mol.Wt.	: 511.0
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Mol.F.	: C27H25ClN10
Mol.Wt.	: 525.1
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Mol.F.	: C7H10N2O2S
Mol.Wt.	: 186.2
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Mol.F.	: C4H3ClN2O
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Inv. Status	: Custom Synthesis

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Mol.F.	: C9H9N3O2
Mol.Wt.	: 191.2
Inv. Status	: In Stock

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Mol.F.	: C8H7N3O2
Mol.Wt.	: 177.2
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Mol.F.	: C9H9N3O2
Mol.Wt.	: 191.2
Inv. Status	: Custom Synthesis

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Mol.Wt.	: 398.5
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Mol.Wt.	: 453.5
Inv. Status	: Custom Synthesis

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Mol.F.	: C21H23N7O3S
Mol.Wt.	: 453.5
Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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