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Pazopanib Desmethyl impurity

SZ CAT No SZ-P013021
CAS No NA
Mol.F. C20H21N7O2S : HCl
Mol.Wt. 423.5 . 36.5
Inv. Status In Stock
Rel. CAS No 1252927-47-1 (free base)


Chemical Name: 5-(4-(2,3-dimethyl-2H-indazol-6-ylamino)pyrimidin-2-ylamino)-2-methylbenzene sulfonamide hydrochloride

Smiles: O=S(C1=CC(NC2=NC=CC(NC3=CC4=NN(C)C(C)=C4C=C3)=N2)=CC=C1C)(N)=O.Cl

Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S Kord
J Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.
 
Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu
Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102
 
Characterization of forced degradation products of pazopanib hydrochloride by UHPLC‐Q‐TOF/MS and in silico toxicity prediction
Prinesh N. Patel  Pradipbhai D. Kalariya  Mahesh Sharma  Prabha Garg  M. V. N Kumar Talluri  S. Gananadhamu  R. Srinivas
Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928
 
Development and validation of a stability indicating RP-HPLC method for the determination of Pazopanib in bulk drug and its pharmaceutical dosage form
Kishore Kumar Reddy Y, J. Raveendra Reddy and N. Devanna
J. Chem. Pharm. Res., 2015, 7(9):127-132
 
Validated RP-HPLC Method Development of Pazopanib in Bulk and its Pharmaceutical Dosage Form
Kiran Kumar Buralla, and Varadarajan Parthasarathy
Pharmaceutical Methods,2020,11,1,21-24.