Paracetamol D4

SZ CAT No:	SZ-P007D01
CAS No	64315-36-2
Mol.F.	C8H5D4NO2
Mol.Wt.	155.2
Inv. Status	Custom Synthesis

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Chemical Name: N-(4-Hydroxyphenyl-2,3,5,6-D4)Acetamide

Synonym: Acetaminophen D4

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: [2H]C1=C(NC(C)=O)C([2H])=C([2H])C(O)=C1[2H]

Thermodynamic properties of paracetamol impurities 4-nitrophenol and 4′-chloroacetanilide and the impact of such impurities on the crystallisation of paracetamol from solution
René R.E.Steendam, LeilaKeshavarz, Briande Souza, Patrick J.Frawley
The Journal of Chemical Thermodynamics Volume 133, June 2019, Pages 85-92

Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS
Sara Ottoboni, Michael Chrubasik, Layla Mir Bruce, Thai Thu Hien Nguyen, Murray Robertson, Blair Johnston,Iain D. H. Oswald, Alastair Florence, and Chris Price
Cryst. Growth Des. 2018, 18, 5, 2750–2758

Separation and determination of impurities in paracetamol, codeine and pitophenone in the presence of fenpiverinium in combined suppository dosage form
Jiří Vojta, Pavel Hanzlík, Aleš Jedlička, Pavel Coufal
J Pharm Biomed Anal. 2015 Jan;102:85-92.

Effects of a structurally related substance on the crystallization of paracetamol
Ali Saleemi, I. I. Onyemelukwe & Zoltan Nagy
Frontiers of Chemical Science and Engineering volume 7, pages79–87(2013)

Paracetamol D4 is chemically N-(4-Hydroxyphenyl-2,3,5,6-D4)Acetamide. It is also known as Acetaminophen D4. Paracetamol D4 is supplied with detailed characterization data compliant with regulatory guideline. Paracetamol D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paracetamol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Paracetamol D4

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