Paracetamol EP Impurity M HCl

SZ CAT No:	SZ-P007022
CAS No	1965310-24-0
Mol.F.	C12H11NO2 : HCl
Mol.Wt.	201.2 : 36.5
Inv. Status	Under Synthesis
Rel. CAS No	1752-24-5 (free base)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: 4,4'-azanediyldiphenol hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC1=CC=C(NC2=CC=C(O)C=C2)C=C1.Cl

Thermodynamic properties of paracetamol impurities 4-nitrophenol and 4′-chloroacetanilide and the impact of such impurities on the crystallisation of paracetamol from solution
René R.E.Steendam, LeilaKeshavarz, Briande Souza, Patrick J.Frawley
The Journal of Chemical Thermodynamics Volume 133, June 2019, Pages 85-92

Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS
Sara Ottoboni, Michael Chrubasik, Layla Mir Bruce, Thai Thu Hien Nguyen, Murray Robertson, Blair Johnston,Iain D. H. Oswald, Alastair Florence, and Chris Price
Cryst. Growth Des. 2018, 18, 5, 2750–2758

Separation and determination of impurities in paracetamol, codeine and pitophenone in the presence of fenpiverinium in combined suppository dosage form
Jiří Vojta, Pavel Hanzlík, Aleš Jedlička, Pavel Coufal
J Pharm Biomed Anal. 2015 Jan;102:85-92.

Effects of a structurally related substance on the crystallization of paracetamol
Ali Saleemi, I. I. Onyemelukwe & Zoltan Nagy
Frontiers of Chemical Science and Engineering volume 7, pages79–87(2013)

Paracetamol EP Impurity M HCl is chemically 4,4'-azanediyldiphenol hydrochloride. Paracetamol EP Impurity M HCl is supplied with detailed characterization data compliant with regulatory guideline. Paracetamol EP Impurity M HCl can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paracetamol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Paracetamol EP Impurity M HCl

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Mol.F.	: C12H11NO2
Mol.Wt.	: 201.2
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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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CAS No	: 1965310-24-0
Mol.F.	: C12H11NO2 : HCl
Mol.Wt.	: 201.2 : 36.5
Inv. Status	: Under Synthesis
Rel. CAS No	: 1752-24-5 (free base)

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Inv. Status	: Custom Synthesis

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