Lenvatinib Impurity 28

SZ CAT No:	SZ-L038047
CAS No	2412398-76-4
Mol.F.	C25H24ClN5O5
Mol.Wt.	509.9
Inv. Status	Limited Stock

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Chemical Name: 4-(3-Chloro-4-(3-cyclopropyl-3-(cyclopropylcarbamoyl)ureido)phenoxy)-7-methoxyquinoline-6-carboxamide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(N)C1=CC2=C(C=C1OC)N=CC=C2OC3=CC(Cl)=C(NC(N(C4CC4)C(NC5CC5)=O)=O)C=C3

Stability indicating UPLC method development and validation of lenvatinib
By Sai, Prasanna A.; Kumar, Meruva Sathish; Kumari, R. V. Valli; Marakatham, S.
From International Journal of Pharmacy and Biological Sciences (2019), 9(3), 605-614

Method validation studies and an inter-laboratory cross validation study of lenvatinib assay in human plasma using LC-MS/MS
By Mano Yuji
From Practical laboratory medicine (2018), 12, e00103

Lenvatinib Impurity 28 is chemically 4-(3-Chloro-4-(3-cyclopropyl-3-(cyclopropylcarbamoyl)ureido)phenoxy)-7-methoxyquinoline-6-carboxamide. Lenvatinib Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Lenvatinib Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lenvatinib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Lenvatinib Impurity 5

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Lenvatinib Impurity 7

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Lenvatinib Impurity 8

SZ CAT No:	: SZ-L038010
CAS No	: 417721-36-9
Mol.F.	: C11H9ClN2O2
Mol.Wt.	: 236.7
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Lenvatinib Impurity 9

SZ CAT No:	: SZ-L038011
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Mol.F.	: C22H20ClN3O5
Mol.Wt.	: 441.9
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Lenvatinib Impurity 10

SZ CAT No:	: SZ-L038012
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Mol.Wt.	: 401.8
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Lenvatinib D4

SZ CAT No:	: SZ-L038D01
CAS No	: 2264050-65-7
Mol.F.	: C21H15D4ClN4O4
Mol.Wt.	: 430.9
Inv. Status	: Custom Synthesis

Lenvatinib D5

SZ CAT No:	: SZ-L038D02
CAS No	: NA
Mol.F.	: C21H14D5ClN4O4
Mol.Wt.	: 431.9
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Lenvatinib Impurity 11

SZ CAT No:	: SZ-L038013
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Mol.F.	: C45H42Cl2N8O8
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Lenvatinib Impurity 12

SZ CAT No:	: SZ-L038015
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Mol.Wt.	: 344.8
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Lenvatinib Impurity 13

SZ CAT No:	: SZ-L038016
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Lenvatinib Impurity 14

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CAS No	: 417722-95-3
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Mol.Wt.	: 463.9
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Lenvatinib Impurity 15

SZ CAT No:	: SZ-L038018
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Mol.F.	: C17H12ClN3O2
Mol.Wt.	: 325.8
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Lenvatinib Impurity 16

SZ CAT No:	: SZ-L038019
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Mol.F.	: C21H17ClN4O3
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Lenvatinib Impurity O

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Lenvatinib Methoxy Impurity

SZ CAT No:	: SZ-L038021
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Lenvatinib Impurity 17

SZ CAT No:	: SZ-L038022
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Mol.F.	: C11H9NO4
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Lenvatinib Impurity 18

SZ CAT No:	: SZ-L038023
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Cyclopropylamine

SZ CAT No:	: SZ-L038024
CAS No	: 765-30-0
Mol.F.	: C3H7N
Mol.Wt.	: 57.1
Inv. Status	: In Stock, 3-4 days for Dispatch
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2-Chloronitrobenzene

SZ CAT No:	: SZ-L038025
CAS No	: 88-73-3
Mol.F.	: C6H4ClNO2
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Cyclopropane Carboxamide

SZ CAT No:	: SZ-L038026
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Lenvatinib Hydroxy Amide Impurity

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Cyclopropyl Urea Impurity

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Lenvatinib Impurity 20

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N-Methyl Lenvatinib

SZ CAT No:	: SZ-L038034
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Lenvatinib Impurity 21

SZ CAT No:	: SZ-L038035
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Mol.Wt.	: 233.2
Inv. Status	: Custom Synthesis

Lenvatinib Impurity 22

SZ CAT No:	: SZ-L038036
CAS No	: NA
Mol.F.	: C10H11ClN2O2
Mol.Wt.	: 226.7
Inv. Status	: Custom Synthesis

Lenvatinib Impurity 24

SZ CAT No:	: SZ-L038038
CAS No	: NA
Mol.F.	: C21H17ClN4O3
Mol.Wt.	: 408.8
Inv. Status	: Custom Synthesis

Lenvatinib Descyclopropyl Impurity

SZ CAT No:	: SZ-L038039
CAS No	: NA
Mol.F.	: C18H15ClN4O4 :CH4O3S
Mol.Wt.	: 386.8 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 417719-51-8 (free base)
Rel. CAT No	: SZ-L038014 ,

Lenvatinib Dimethyl Impurity

SZ CAT No:	: SZ-L038040
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Mol.F.	: C20H19ClN4O4 : CH4O3S
Mol.Wt.	: 414.8 : 96.1
Inv. Status	: In Stock
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Rel. CAT No	: SZ-L038020 ,

O-Desmethyl Lenvatinib

SZ CAT No:	: SZ-L038041
CAS No	: 417717-04-5
Mol.F.	: C20H17ClN4O4
Mol.Wt.	: 412.8
Inv. Status	: In Stock

Meldrum’s Acid

SZ CAT No:	: SZ-L038042
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Mol.F.	: C6H8O4
Mol.Wt.	: 144.1
Inv. Status	: Custom Synthesis

5-(Methoxymethylene) Meldrum’s Acid

SZ CAT No:	: SZ-L038043
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Mol.Wt.	: 186.2
Inv. Status	: Custom Synthesis

Lenvatinib Impurity 25

SZ CAT No:	: SZ-L038044
CAS No	: 205448-64-2
Mol.F.	: C16H17NO7
Mol.Wt.	: 335.3
Inv. Status	: Custom Synthesis

Lenvatinib Impurity 26

SZ CAT No:	: SZ-L038045
CAS No	: 205448-65-3
Mol.F.	: C12H11NO4
Mol.Wt.	: 233.2
Inv. Status	: Custom Synthesis

Lenvatinib Impurity 27

SZ CAT No:	: SZ-L038046
CAS No	: 253801-34-2
Mol.F.	: C12H9ClN2O4S
Mol.Wt.	: 312.7
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2491-60-3 (sodium salt)

Lenvatinib Impurity 28

SZ CAT No:	: SZ-L038047
CAS No	: 2412398-76-4
Mol.F.	: C25H24ClN5O5
Mol.Wt.	: 509.9
Inv. Status	: Limited Stock

Lenvatinib Impurity 28

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