Ketoconazole D3

SZ CAT No:	SZ-K001D01
CAS No	1217766-70-5
Mol.F.	C26H25D3Cl2N4O4
Mol.Wt.	534.5
Inv. Status	In Stock

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Chemical Name: 1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one-2,2,2-d3

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=C(C=CC(Cl)=C1)[C@]2(O[C@H](COC3=CC=C(N4CCN(C(C([2H])([2H])[2H])=O)CC4)C=C3)CO2)CN5C=CN=C5

Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresis–mass spectrometry
Mar´ıa Castro-Puyana a, Carmen Garc´ıa-Ruiz a, Alejandro Cifuentes b, Antonio L. Crego a, Maria Luisa Marina
Journal of Chromatography A, 1114 (2006) 170–177

Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor
Aneta Grycová , Aneta Dořičáková 1, Zdeněk Dvořák
Toxicol Lett . 2015 Dec 3;239(2):67-72

Ion-pairing liquid chromatographic method determination of ketoconazole and stress degradation in pharmaceutical formulations with fluorescence detection
Wisanu Thongchai
Brazilian Journal of Pharmaceutical Sciences Sci. vol.56

Development and Validation of Stability-Indicating Method for the Simultaneous Determination of Ketoconazole and Beauvericin in Pharmaceutical Tablets
Tingting Tian, Min Yang, Zhongxi Zhao, Yuxia Luan, Xuan Tang, Meihua Zhu, Yan Liu
Journal of Chromatographic Science, Volume 54, Issue 3, 1 March 2016, Pages 361–366

Ketoconazole D3 is chemically 1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one-2,2,2-d3. Ketoconazole D3 is supplied with detailed characterization data compliant with regulatory guideline. Ketoconazole D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ketoconazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Ketoconazole D3

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Mol.F.	: C26H28Cl2N4O4
Mol.Wt.	: 531.4
Inv. Status	: In Stock

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Mol.F.	: C26H26Cl2N4O4
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Mol.F.	: C38H42Cl2N6O6
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Mol.F.	: C26H28Cl2N4O4
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Mol.F.	: C21H20Cl2N2O5S
Mol.Wt.	: 483.4
Inv. Status	: In Stock

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Mol.F.	: C14H14Cl2N2O3
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Inv. Status	: Limited Stock

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Mol.Wt.	: 547.4
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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: In Stock

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Mol.Wt.	: 446.1
Inv. Status	: Custom Synthesis

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Mol.F.	: C21H20Cl2N2O5S
Mol.Wt.	: 483.4
Inv. Status	: Custom Synthesis

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Mol.Wt.	: 329.2
Inv. Status	: In Stock

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Inv. Status	: In Stock

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Inv. Status	: In Stock

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Mol.F.	: C18H15BrCl2O4
Mol.Wt.	: 446.1
Inv. Status	: In Stock

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Inv. Status	: In Stock

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CAS No	: 1217766-70-5
Mol.F.	: C26H25D3Cl2N4O4
Mol.Wt.	: 534.5
Inv. Status	: In Stock

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Mol.Wt.	: 539.5
Inv. Status	: Custom Synthesis

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Mol.Wt.	: 611.5
Inv. Status	: Under Synthesis

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Inv. Status	: Custom Synthesis

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Mol.Wt.	: 329.2
Inv. Status	: In Stock

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Inv. Status	: In Stock