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Hydroxychloroquine Sulfate EP Impurity C

SZ CAT No SZ-H004002
CAS No 159358-29-9
Mol.F. C16H22ClN3O : HCl
Mol.Wt. 307.8 : 36.5
Inv. Status In Stock
Rel. CAS No 4298-15-1 (free base)


Chemical Name: 2-[[(4RS)-4-[(7-chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol Hydrochloride (as per EP); 2-({4-[(7-Chloroquinolin-4-yl)amino]pentyl}amino)ethan-1-ol Hydrochloride (as per USP)

Synonym: Hydroxychloroquine USP related impurity a ; Desethylhydroxychloroquine

Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR
Vaijanath G. Dongrea,∗, Pradeep D. Ghugarea, Pravin Karmusea, Dharmendra Singhb, Atul Jadhav b, Ashok Kumar
Journal of Pharmaceutical and Biomedical Analysis 49 (2009) 873–879
 
Repository drugs. VIII. Ester and amide congeners of amodiaquine, hydroxychloroquine, oxychloroquine, primaquine, quinacrine, and related substances as potential long-acting antimalarial agents
Edward F. Elslager, Frank H. Tendick, and Leslie M. Werbel
J. Med. Chem. 1969, 12, 4, 600–607
 
Recent Clinical and Preclinical Studies of Hydroxychloroquine on RNA Viruses and Chronic Diseases: A Systematic Review
Immacolata Faraone ,Fabiana Labanca ,Maria Ponticelli 1,Nunziatina De Tommasi ,andLuigi Milella
Molecules 2020, 25(22), 5318
 
Analytical methods for the determination of hydroxychloroquine in various matrices
Alankar shrivastava
Int J App Pharm, Vol 12, Issue 4, 2020, 55-61