Formoterol Hemifumarate

SZ CAT No:	SZ-F005011
CAS No	43229-80-7
Mol.F.	C19H24N2O4 : 1/2(C4H4O4)
Mol.Wt.	344.41 : 1/2(116.1)
Inv. Status	Custom Synthesis
Rel. CAS No	73573-87-2 (free base) ; 183814-30-4 (Fumarate salt)
Shipping Condition	Ambient Temperature

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Chemical Name: N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OC1=C(NC([H])=O)C=C([C@H](CN[C@H](C)CC2=CC=C(OC)C=C2)O)C=C1.OC(/C=C/C(O)=O)=O

A novel RP-HPLC Method for the Simultaneous Estimation of Aclidinium Bromide and Formoterol Fumarate in Bulk and Pharmaceutical Dosage Forms with Stability Studies
By Polisetty, Sai Suharshini; Guruva, Reddy M.
From International Journal of Pharmacy and Pharmaceutical Research (2020), 19(3), 530-544

Analytical method development and validation of formoterol and glycopyrrolatein pure and dosage forms by using RP-HPLC
By Mallikarjuna, R.; Reddy, L. Ramachandra; Dhachinamoorthi, D.
From European Journal of Biomedical and Pharmaceutical Sciences (2019), 6(10), 298-307

Simultaneous RP-HPLC method for determination of impurities in formoterol fumarate and aclidinium bromide in pharmaceutical dosage forms
By Gowda, Ravi; Sathe, Padmakar A.
From International Journal of Chemical and Pharmaceutical Analysis (2016), 3(3), 1-6

Formoterol Hemifumarate is chemically N-(2-Hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate. Formoterol Hemifumarate is supplied with detailed characterization data compliant with regulatory guideline. Formoterol Hemifumarate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Formoterol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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SZ CAT No:	: SZ-F005D01
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Mol.F.	: C19H21N2O4D3
Mol.Wt.	: 348.4
Inv. Status	: Custom Synthesis

(R,R)-Formoterol-d3

SZ CAT No:	: SZ-F005D02
CAS No	: 1198353-13-7
Mol.F.	: C19H21N2O4D3
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Formoterol-13C-d3 Hemifumarate

SZ CAT No:	: SZ-F005D03
CAS No	: NA
Mol.F.	: C1813CH21D3N2O4 : 1/2(C4H4O4)
Mol.Wt.	: 348.4 : 1/2(116.1)
Inv. Status	: Custom Synthesis

Formoterol-D7

SZ CAT No:	: SZ-F005D04
CAS No	: NA
Mol.F.	: C19H17N2O4D7
Mol.Wt.	: 351.5
Inv. Status	: Custom Synthesis

Formoterol EP Impurity A

SZ CAT No:	: SZ-F005002
CAS No	: 150513-24-9
Mol.F.	: C18H24N2O3
Mol.Wt.	: 316.4
Inv. Status	: In Stock

Formoterol EP Impurity B Fumarate

SZ CAT No:	: SZ-F005003
CAS No	: 1795137-04-0
Mol.F.	: C18H22N2O4 : C4H4O4
Mol.Wt.	: 330.4 : 116.1
Inv. Status	: In Stock

Formoterol EP Impurity C

SZ CAT No:	: SZ-F005004
CAS No	: 1795135-61-3
Mol.F.	: C20H26N2O4
Mol.Wt.	: 358.4
Inv. Status	: In Stock

Formoterol EP Impurity D

SZ CAT No:	: SZ-F005005
CAS No	: 1795133-96-8
Mol.F.	: C20H26N2O4
Mol.Wt.	: 358.4
Inv. Status	: In Stock

Formoterol EP Impurity E

SZ CAT No:	: SZ-F005006
CAS No	: 1616967-26-0
Mol.F.	: C20H26N2O4
Mol.Wt.	: 358.4
Inv. Status	: In Stock

Formoterol EP Impurity F

SZ CAT No:	: SZ-F005007
CAS No	: 1795129-59-7
Mol.F.	: C37H46N4O6
Mol.Wt.	: 642.8
Inv. Status	: In Stock

Formoterol EP Impurity G HCl

SZ CAT No:	: SZ-F005008
CAS No	: 3706-26-1
Mol.F.	: C10H15NO : HCl
Mol.Wt.	: 165.2 : 36.5
Inv. Status	: In Stock

Formoterol EP Impurity I

SZ CAT No:	: SZ-F005009
CAS No	: 532414-36-1
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Formoterol EP Impurity I (R,S-isomer)

SZ CAT No:	: SZ-F005010
CAS No	: 67346-51-4
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Formoterol Hemifumarate

SZ CAT No:	: SZ-F005011
CAS No	: 43229-80-7
Mol.F.	: C19H24N2O4 : 1/2(C4H4O4)
Mol.Wt.	: 344.41 : 1/2(116.1)
Inv. Status	: Custom Synthesis

Formoterol Sulfate

SZ CAT No:	: SZ-F005012
CAS No	: NA
Mol.F.	: C19H24N2O7S
Mol.Wt.	: 424.5
Inv. Status	: Custom Synthesis

(S,S)-Formoterol

SZ CAT No:	: SZ-F005013
CAS No	: 67346-48-9
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: Limited Stock

(R,R)-Formoterol

SZ CAT No:	: SZ-F005014
CAS No	: 67346-49-0
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Formoterol EP Impurity H

SZ CAT No:	: SZ-F005015
CAS No	: 2514947-17-0
Mol.F.	: C26H30N2O4
Mol.Wt.	: 434.5
Inv. Status	: In Stock

5-Formyl-2-Hydroxyformanilide

SZ CAT No:	: SZ-F005016
CAS No	: 903563-43-9
Mol.F.	: C8H7NO3
Mol.Wt.	: 165.2
Inv. Status	: In Stock

N,O-Dibenzylated Formoterol

SZ CAT No:	: SZ-F005017
CAS No	: 43229-70-5
Mol.F.	: C33H36N2O4
Mol.Wt.	: 524.7
Inv. Status	: In Stock

Formoterol Amine

SZ CAT No:	: SZ-F005018
CAS No	: 43229-65-8
Mol.F.	: C17H21NO
Mol.Wt.	: 255.4
Inv. Status	: In Stock

Formoterol Bromide

SZ CAT No:	: SZ-F005019
CAS No	: 43229-01-2
Mol.F.	: C15H12BrNO4
Mol.Wt.	: 350.2
Inv. Status	: Custom Synthesis

Arformoterol Tartrate

SZ CAT No:	: SZ-F005020
CAS No	: 200815-49-2
Mol.F.	: C19H24N2O4 : C4H6O6
Mol.Wt.	: 344.4 : 150.1
Inv. Status	: In Stock

Formoterol Impurity 1

SZ CAT No:	: SZ-F005021
CAS No	: 49861-92-9
Mol.F.	: C18H22N2O4
Mol.Wt.	: 330.4
Inv. Status	: In Stock

Arformoterol tartrate (1S, 2R) Isomer

SZ CAT No:	: SZ-F005023
CAS No	: 67346-50-3
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: In Stock

Formoterol Deshydroxy Impurity

SZ CAT No:	: SZ-F005025
CAS No	: 477552-93-5
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 3

SZ CAT No:	: SZ-F005026
CAS No	: 143687-23-4
Mol.F.	: C33H36N2O4
Mol.Wt.	: 524.7
Inv. Status	: Out of Stock, Custom Synthesis

Formoterol Impurity 4

SZ CAT No:	: SZ-F005028
CAS No	: 143687-25-6
Mol.F.	: C33H36N2O4
Mol.Wt.	: 524.7
Inv. Status	: Limited Stock

Formoterol Fumarate Dihydrate

SZ CAT No:	: SZ-F005030
CAS No	: 183814-30-4
Mol.F.	: 2(C19H24N2O4) : C4H4O4 : 2(H2O)
Mol.Wt.	: 2(344.4) : 116.1 : 2(18.0)
Inv. Status	: In Stock

Formoterol Impurity 5

SZ CAT No:	: SZ-F005031
CAS No	: NA
Mol.F.	: C20H26N2O4
Mol.Wt.	: 358.4
Inv. Status	: Limited Stock

Arformoterol Impurity 1

SZ CAT No:	: SZ-F005032
CAS No	: NA
Mol.F.	: C21H28N2O3
Mol.Wt.	: 356.5
Inv. Status	: Custom Synthesis

Arformoterol Impurity 2

SZ CAT No:	: SZ-F005033
CAS No	: 876753-51-4
Mol.F.	: C15H15NO5
Mol.Wt.	: 289.3
Inv. Status	: Custom Synthesis

O-Debenzyl Amino Impurity

SZ CAT No:	: SZ-F005034
CAS No	: NA
Mol.F.	: C26H32N2O3
Mol.Wt.	: 420.6
Inv. Status	: Custom Synthesis

Arformoterol Impurity 3

SZ CAT No:	: SZ-F005035
CAS No	: NA
Mol.F.	: C16H17NO3
Mol.Wt.	: 271.3
Inv. Status	: In Stock

Arformoterol Impurity 4

SZ CAT No:	: SZ-F005036
CAS No	: NA
Mol.F.	: C16H17NO2
Mol.Wt.	: 255.3
Inv. Status	: Custom Synthesis

Arformoterol Diformylated Amino Impurity

SZ CAT No:	: SZ-F005037
CAS No	: NA
Mol.F.	: C35H38N2O5
Mol.Wt.	: 566.7
Inv. Status	: Custom Synthesis

Arformoterol O-Formyl N-Acetyl Amino Impurity

SZ CAT No:	: SZ-F005038
CAS No	: NA
Mol.F.	: C36H40N2O5
Mol.Wt.	: 580.7
Inv. Status	: Custom Synthesis

Arformoterol Amino Dimer Impurity

SZ CAT No:	: SZ-F005039
CAS No	: 112376-21-3
Mol.F.	: C20H27NO2
Mol.Wt.	: 313.4
Inv. Status	: Custom Synthesis

R(+) Diphenyl Amine Dimer Impurity

SZ CAT No:	: SZ-F005040
CAS No	: 10024-74-5
Mol.F.	: C16H19N
Mol.Wt.	: 225.3
Inv. Status	: Custom Synthesis

Arformoterol Tartrate

SZ CAT No:	: SZ-F005041
CAS No	: NA
Mol.F.	: C27H32N2O4
Mol.Wt.	: 448.6
Inv. Status	: Custom Synthesis

Arformoterol Impurity 5

SZ CAT No:	: SZ-F005042
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 7

SZ CAT No:	: SZ-F005044
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 8

SZ CAT No:	: SZ-F005045
CAS No	: NA
Mol.F.	: C21H28N2O4
Mol.Wt.	: 372.5
Inv. Status	: Limited Stock

Formoterol Benzylic Glucuronide (mixture of diastereomers)

SZ CAT No:	: SZ-F005046
CAS No	: NA
Mol.F.	: C25H32N2O10
Mol.Wt.	: 520.5
Inv. Status	: Custom Synthesis

Formoterol Phenolic Glucuronide

SZ CAT No:	: SZ-F005047
CAS No	: 615551-59-2
Mol.F.	: C25H32N2O10
Mol.Wt.	: 520.5
Inv. Status	: Custom Synthesis

Formoterol Impurity 9

SZ CAT No:	: SZ-F005048
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 10

SZ CAT No:	: SZ-F005049
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol-D6 Fumarate

SZ CAT No:	: SZ-F005D05
CAS No	: NA
Mol.F.	: C19H18D6N2O4 : C4H4O4
Mol.Wt.	: 350.4 : 116.1
Inv. Status	: Custom Synthesis

Formoterol Ethyl Ether Impurity

SZ CAT No:	: SZ-F005050
CAS No	: NA
Mol.F.	: C21H28N2O4
Mol.Wt.	: 372.5
Inv. Status	: In Stock

Benzyl Glucuronide of Formoterol

SZ CAT No:	: SZ-F005052
CAS No	: NA
Mol.F.	: C25H32N2O10
Mol.Wt.	: 520.5
Inv. Status	: Custom Synthesis

N-Nitroso Formoterol

SZ CAT No:	: SZ-F005053
CAS No	: NA
Mol.F.	: C19H23N3O5
Mol.Wt.	: 373.4
Inv. Status	: Limited Stock

Formoterol Impurity 12

SZ CAT No:	: SZ-F005054
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 13

SZ CAT No:	: SZ-F005055
CAS No	: NA
Mol.F.	: C19H24N2O3
Mol.Wt.	: 328.4
Inv. Status	: Custom Synthesis

Formoterol EP Impurity A Fumarate

SZ CAT No:	: SZ-F005043
CAS No	: NA
Mol.F.	: C18H24N2O3 : 1/2(C4H4O4)
Mol.Wt.	: 316.4 : 1/2(116.1)
Inv. Status	: In Stock

Formoterol EP Impurity B

SZ CAT No:	: SZ-F005056
CAS No	: 1224588-66-2
Mol.F.	: C18H22N2O4
Mol.Wt.	: 330.4
Inv. Status	: In Stock

Formoterol

SZ CAT No:	: SZ-F005001
CAS No	: 73573-87-2
Mol.F.	: C19H24N2O4
Mol.Wt.	: 344.4
Inv. Status	: Under Synthesis

Rac N-Deformyl Formoterol

SZ CAT No:	: SZ-F005061
CAS No	: 652994-19-9
Mol.F.	: C18H24N2O3
Mol.Wt.	: 316.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 11

SZ CAT No:	: SZ-F005051
CAS No	: 126002-14-0
Mol.F.	: C11H15NO2
Mol.Wt.	: 193.2
Inv. Status	: In Stock

Formoterol Impurity 14

SZ CAT No:	: SZ-F005062
CAS No	: NA
Mol.F.	: C14H19NO5
Mol.Wt.	: 281.3
Inv. Status	: In Stock

Arformoterol Impurity 6

SZ CAT No:	: SZ-F005063
CAS No	: NA
Mol.F.	: C21H26N2O6
Mol.Wt.	: 402.4
Inv. Status	: Custom Synthesis

Formoterol Impurity 15

SZ CAT No:	: SZ-F005064
CAS No	: NA
Mol.F.	: C24H30N2O9
Mol.Wt.	: 490.5
Inv. Status	: Under Synthesis

Arformoterol Impurity 7

SZ CAT No:	: SZ-F005065
CAS No	: NA
Mol.F.	: C21H26N2O6
Mol.Wt.	: 402.4
Inv. Status	: Custom Synthesis

N-nitroso (S,S)-formoterol

SZ CAT No:	: SZ-F005066
CAS No	: NA
Mol.F.	: C19H23N3O5
Mol.Wt.	: 373.4
Inv. Status	: Custom Synthesis

Formoterol Hemifumarate

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