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Estradiol Valerate EP Impurity E

SZ CAT No SZ-E005006
CAS No 63042-28-4
Mol.F. C28H40O4
Mol.Wt. 440.6
Inv. Status In Stock


Chemical Name: Estra-1,3,5(10)-trien-3,17β-diyl dipentanoate (as per EP) ; Estra-1,3,5(10)-trien-3,17β-diyl divalerate ( as per USP)

Synonym: Estradiol divalerate

Smiles: C[C@@]12[C@](OC(CCCC)=O)([H])CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(CCCC)=O)=C4)[C@@]3([H])CC2

Inchi: InChI=1S/C24H34O3/c1-4-5-6-23(26)27-22-12-10-20-19-8-7-16-15(2)21(25)11-9-17(16)18(19)13-14-24(20,22)3/h9,11,18-20,22,25H,4-8,10,12-14H2,1-3H3/t18-,19-,20+,22+,24+/m1/s1

Validated RP-HPLC method for the determination of estradiol valerate in bulk and pharmaceutical formulations
M. Madhu1 *, Satyadev T. N. V. S. S.1 , G. Hephzibah1 and T. V. Reddy
Der Pharmacia Lettre, 2016, 8 (4):50-61
 
Determination of estradiol and its degradation products by liquid chromatography
Lucie Havlíková, Lucie Nováková, Ludmila Matysová, Jan Sícha
Journal of Chromatography A 1119(1-2):216-23
 
Determination of Related Substances in Estradiol Valerate Tablet by Use of HPLC Method
Du, Biying
Current Pharmaceutical Analysis, Volume 14, Number 5, 2018, pp. 513-518(6)