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Estradiol Valerate EP Impurity B

SZ CAT No SZ-E005003
CAS No 21881-45-8
Mol.F. C23H32O3
Mol.Wt. 356.5
Inv. Status In Stock


Chemical Name: 17β-Hydroxyestra-1,3,5(10)-trien-3-yl pentanoate (as per EP)

Synonym: Estradiol, 3-valerate

Smiles: O[C@@]1([H])CC[C@@]2([H])[C@]3([H])CCC4=C(C=CC(OC(CCCC)=O)=C4)[C@@]3([H])CC[C@]12C

Inchi: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

Validated RP-HPLC method for the determination of estradiol valerate in bulk and pharmaceutical formulations
M. Madhu1 *, Satyadev T. N. V. S. S.1 , G. Hephzibah1 and T. V. Reddy
Der Pharmacia Lettre, 2016, 8 (4):50-61
 
Determination of estradiol and its degradation products by liquid chromatography
Lucie Havlíková, Lucie Nováková, Ludmila Matysová, Jan Sícha
Journal of Chromatography A 1119(1-2):216-23
 
Determination of Related Substances in Estradiol Valerate Tablet by Use of HPLC Method
Du, Biying
Current Pharmaceutical Analysis, Volume 14, Number 5, 2018, pp. 513-518(6)