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Erlotinib Impurity 37

SZ CAT No SZ-E018061
CAS No NA
Mol.F. C16H22N2O5
Mol.Wt. 322.4
Inv. Status Custom Synthesis


Chemical Name: 1-(6,7-Bis(2-Methoxyethoxy)-4a,8a-Dihydroquinazolin-4-yl)ethan-1-one

Smiles: COCCOC(C(OCCOC)=C1)=CC2C1N=CN=C2C(C)=O

Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Chris Twelvesa, Jose´ M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Jose´ Baselga
European journal of cancer 44 (2008) 419 – 426
 
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BabuC1, Narasimha  RaoK.L1,  DevannaN1, Suresh Reddy  K.V.N
 
Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K
Jinghuan Zhai, Junrui Zhao, Zhenzhen Chen, Changwei Xiao, Xijian Liu, Lijuan Zhang, and Jie Lu
J. Chem. Eng. Data 2017, 62, 1, 516–524
 
Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector
Chandrashekara KARUNAKARA, Udupi APARNA, Venkateshappa CHANDREGOWDA, and Chandrasekara G. REDDY
Analytical Sciences 28(3):305-8