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Erlotinib Impurity 36

SZ CAT No SZ-E018060
Mol.F. C14H19ClN2O4
Mol.Wt. 314.8
Inv. Status Custom Synthesis

Chemical Name: 4-Chloro-6,7-bis(2-methoxyethoxy)-4a,8a-dihydroquinazoline


Inchi: InChI=1S/C15H15NO/c1-11-8-9-14(16-2)13(10-11)15(17)12-6-4-3-5-7-12/h3-10,16H,1-2H3

Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Chris Twelvesa, Jose´ M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Jose´ Baselga
European journal of cancer 44 (2008) 419 – 426
Development and validation of a stability indicating HPLC method for the quantification of impurities in Erlotinib hydrochloride dosage forms
BabuC1, Narasimha  RaoK.L1,  DevannaN1, Suresh Reddy  K.V.N
Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K
Jinghuan Zhai, Junrui Zhao, Zhenzhen Chen, Changwei Xiao, Xijian Liu, Lijuan Zhang, and Jie Lu
J. Chem. Eng. Data 2017, 62, 1, 516–524
Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector
Chandrashekara KARUNAKARA, Udupi APARNA, Venkateshappa CHANDREGOWDA, and Chandrasekara G. REDDY
Analytical Sciences 28(3):305-8