Desethyl Amiodarone D4

SZ CAT No:	SZ-A007D02
CAS No	1184978-11-7
Mol.F.	C23H21D4I2NO3
Mol.Wt.	621.3
Inv. Status	Custom Synthesis
Rel. CAS No	1189960-80-2 (HCl salt)

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Chemical Name: (2-Butylbenzofuran-3-yl)(4-(2-(ethylamino)ethoxy-1,1,2,2-d4)-3,5-diiodophenyl)methanone

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=CC(I)=C(OC([2H])([2H])C([2H])([2H])NCC)C(I)=C1)C(C2=CC=CC=C2O3)=C3CCCC

Quality by design (QbD) based development and validation of an HPLC method for amiodarone hydrochloride and its impurities in the drug substance
S. Karmarkar ∗, X. Yang, R. Garber, A. Szajkovics, M. Koberda
Journal of Pharmaceutical and Biomedical Analysis 100 (2014) 167–174

Validation of a Stability-Indicating HPLC Method for the Determination of Amiodarone HCl and Its Related Substances in Amiodarone HCl Injection
Matthew J. Christopherson,* Kenton J. Yoder, and R. Brent Miller
Journal of liquid chromatography & related technologies vol. 27, No. 1, pp. 95–111, 2004

Stability-indicating HPLC method for determination of amiodarone hydrochloride and its impurities in tablets: a detailed forced degradation study
Ana Silva Coelho1 , Igor Felipe Rodrigues Ribeiro1 , Eduardo Burgarelli Lages
Braz. J. Pharm. Sci. vol.56

Validation of a Stability Indicating LC Method for Amiodarone HCL and Related Substances
M. A. Khan, S. Kumar, J. Jayachandran, S. V. Vartak, A. Bhartiya, S. Sinha
Chromatographia volume 61, pages599–607(2005)

Desethyl Amiodarone D4 is chemically (2-Butylbenzofuran-3-yl)(4-(2-(ethylamino)ethoxy-1,1,2,2-d4)-3,5-diiodophenyl)methanone. Desethyl Amiodarone D4 is supplied with detailed characterization data compliant with regulatory guideline. Desethyl Amiodarone D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Amiodarone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Desethyl Amiodarone D4

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SZ CAT No:	: SZ-A007014
CAS No	: 4265-27-4
Mol.F.	: C12H14O
Mol.Wt.	: 174.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007D03
CAS No	: 1216376-62-3
Mol.F.	: C21H15D4BrI2O3
Mol.Wt.	: 657.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-A007001
CAS No	: 19774-82-4
Mol.F.	: C25H29I2NO3 : HCl
Mol.Wt.	: 645.3 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007D01
CAS No	: 1217169-60-2
Mol.F.	: C25H25D4I2NO3
Mol.Wt.	: 649.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-A007010
CAS No	: 757220-04-5
Mol.F.	: C21H21I2NO3 : HCl
Mol.Wt.	: 589.2 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007002
CAS No	: 23551-25-9
Mol.F.	: C25H31NO3
Mol.Wt.	: 393.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007003
CAS No	: 96027-74-6
Mol.F.	: C23H25I2NO3 : HCl
Mol.Wt.	: 617.3 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007004
CAS No	: 1397201-93-2
Mol.F.	: C25H30INO3 : HCl
Mol.Wt.	: 519.4 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007005
CAS No	: 1951-26-4
Mol.F.	: C19H16I2O3
Mol.Wt.	: 546.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007006
CAS No	: 52490-15-0
Mol.F.	: C19H18O3
Mol.Wt.	: 294.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007007
CAS No	: 147030-50-0
Mol.F.	: C19H17IO3
Mol.Wt.	: 420.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007008
CAS No	: NA
Mol.F.	: C26H31I2NO4 : HCl
Mol.Wt.	: 675.3 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007009
CAS No	: 869-24-9
Mol.F.	: C6H14ClN : HCl
Mol.Wt.	: 135.6 : 36.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007015
CAS No	: NA
Mol.F.	: C19H17IO4
Mol.Wt.	: 436.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007018
CAS No	: NA
Mol.F.	: C21H20I2O3
Mol.Wt.	: 574.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007016
CAS No	: NA
Mol.F.	: C12H15NO2
Mol.Wt.	: 205.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-A007011
CAS No	: 83790-87-8
Mol.F.	: C20H20O3
Mol.Wt.	: 308.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007012
CAS No	: 318267-30-0
Mol.F.	: C25H29I2NO4
Mol.Wt.	: 661.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-A007013
CAS No	: NA
Mol.F.	: C25H31NO3
Mol.Wt.	: 393.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-A007D02
CAS No	: 1184978-11-7
Mol.F.	: C23H21D4I2NO3
Mol.Wt.	: 621.3
Inv. Status	: Custom Synthesis

Desethyl Amiodarone D4

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SZ CAT No:	: SZ-A007017
CAS No	: 678982-38-2
Mol.F.	: C23H24I2N2O4
Mol.Wt.	: 646.3
Inv. Status	: In Stock