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Cefaclor EP Impurity H

SZ CAT No SZ-C067009
CAS No NA
Mol.F. C23H21ClN4O5S
Mol.Wt. 501.0
Inv. Status Custom Synthesis


Chemical Name: (6R,7R)-7-[[(2R)-2-[[(2R)-2-Amino-2-phenylacetyl]amino]-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per EP)

Synonym: N-Phenylglycyl Cefaclor ; D-Phenylglycyl Cefaclor

Smiles: O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](NC([C@H](N)C3=CC=CC=C3)=O)C4=CC=CC=C4)=O)C1=O)O

Inchi: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-12,15H,1,7,17H2,(H,18,20)(H,22,23)/t10-,11-,12?,15-/m1/s1

Multidimensional evaluation of impurity profiles for generic cephalexin and cefaclor antibiotics
B.A. Olsen*, S.W. Baertschi and R.M. Riggin
Journal of Chromatography, 648 (1993) 165-173
 
Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities
Hecheng Wang,1,2 Haiwei Huang,3 Jin Cao,3 Dehua Chui,2 and Shengyuan Xiao
Hindawi Publishing Corporation BioMed Research International Volume 2015, Article ID 697958, 13 pages
 
The Degradation Mechanism of an Oral Cephalosporin: Cefaclor
Bartolomê Vilanova  Josefa Donoso  Francisco Muñoz  Francisco García‐Blanco
helvetica chimica acta - vol. 79 (1996)