Cefaclor EP Impurity E

SZ CAT No:	SZ-C067006
CAS No	188915-50-6
Mol.F.	C14H14ClN3O4S
Mol.Wt.	355.8
Inv. Status	Custom Synthesis

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Chemical Name: 2-[[(2R)-2-Amino-2-phenylacetyl]amino]-2-(5-chloro-4-oxo-3,4-dihydro-2H-1,3-thiazin-2-yl)acetic acid (as per EP)

Synonym: Cefaclor Open-Ring Impurity

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(O)C(NC([C@H](N)C1=CC=CC=C1)=O)C(N2)SC=C(Cl)C2=O

Multidimensional evaluation of impurity profiles for generic cephalexin and cefaclor antibiotics
B.A. Olsen*, S.W. Baertschi and R.M. Riggin
Journal of Chromatography, 648 (1993) 165-173

Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities
Hecheng Wang,1,2 Haiwei Huang,3 Jin Cao,3 Dehua Chui,2 and Shengyuan Xiao
Hindawi Publishing Corporation BioMed Research International Volume 2015, Article ID 697958, 13 pages

The Degradation Mechanism of an Oral Cephalosporin: Cefaclor
Bartolomê Vilanova Josefa Donoso Francisco Muñoz Francisco García‐Blanco
helvetica chimica acta - vol. 79 (1996)

Cefaclor EP Impurity E is chemically 2-[[(2R)-2-Amino-2-phenylacetyl]amino]-2-(5-chloro-4-oxo-3,4-dihydro-2H-1,3-thiazin-2-yl)acetic acid (as per EP). It is also known as Cefaclor Open-Ring Impurity . Cefaclor EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Cefaclor EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefaclor.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Cefaclor EP Impurity E

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