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Anastrozole EP impurity B

SZ CAT No SZ-A003003
CAS No 1216898-82-6
Mol.F. C30H31N9
Mol.Wt. 517.6
Inv. Status In Stock


Chemical Name: (2RS)-2,3-bis[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile (as per EP) ; 2,3-Bis(3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl)-2-methylpropionitrile (as per USP)

Synonym: Anastrozole USP Related Compound B ; Anastrozole Dimer Impurity

LC and LC–MS/MS study of forced decomposition behavior of anastrozole and establishment of validated stability-indicating analytical method for impurities estimation in low dose anastrozole tablets
Y. Ramachandra Reddy b,∗, Srinivasan R. Nandana,b,∗∗, D. Vijaya Bharathi c, B. Nagarajua, S. Saidu Reddy b, L.K. Ravindranathb, V. Suryanarayan Rao b
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 397–404

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
Yusra A Alyafee,1,2 Manal Alaamery,1 Shahad Bawazeer,1 Mansour S Almutairi,1 Badr Alghamdi,1 Nawaf Alomran,1 Atia Sheereen,1 Maha Daghestani,2 and Salam Massadeh1,3
Int J Nanomedicine. 2018; 13: 199–208.

Isolation and characterization of process related impurities in anastrozole active pharmaceutical ingredient
S. G. Hiriyanna*; K. Basavaiah
J. Braz. Chem. Soc., Vol. 19, No. 3, 397-404, 2008.

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