Anastrozole D12

SZ CAT No:	SZ-A003D01
CAS No	120512-32-5
Mol.F.	C17H7D12N5
Mol.Wt.	305.5
Inv. Status	Custom Synthesis

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Chemical Name: 2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-(methyl-d3)propanenitrile-3,3,3-d3)

Synonym: Anastrol-d12 ; Arimidex-D12

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: N#CC(C([2H])([2H])[2H])(C1=CC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C#N)=CC(CN2C=NC=N2)=C1)C([2H])([2H])[2H]

LC and LC–MS/MS study of forced decomposition behavior of anastrozole and establishment of validated stability-indicating analytical method for impurities estimation in low dose anastrozole tablets
Y. Ramachandra Reddy b,∗, Srinivasan R. Nandana,b,∗∗, D. Vijaya Bharathi c, B. Nagarajua, S. Saidu Reddy b, L.K. Ravindranathb, V. Suryanarayan Rao b
Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 397–404

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
Yusra A Alyafee,1,2 Manal Alaamery,1 Shahad Bawazeer,1 Mansour S Almutairi,1 Badr Alghamdi,1 Nawaf Alomran,1 Atia Sheereen,1 Maha Daghestani,2 and Salam Massadeh1,3
Int J Nanomedicine. 2018; 13: 199–208.

Isolation and characterization of process related impurities in anastrozole active pharmaceutical ingredient
S. G. Hiriyanna*; K. Basavaiah
J. Braz. Chem. Soc., Vol. 19, No. 3, 397-404, 2008.

Anastrozole D12 is chemically 2,2'-(5-((1H-1,2,4-Triazol-1-yl)methyl)-1,3-phenylene)bis(2-(methyl-d3)propanenitrile-3,3,3-d3). It is also known as Anastrol-d12 ; Arimidex-D12. Anastrozole D12 is supplied with detailed characterization data compliant with regulatory guideline. Anastrozole D12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Anastrozole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Anastrozole D12

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