Aciclovir EP Impurity J

Compatible stability of vidarabine monophosphate for injection and aciclovir injection
By Liu, Yuelin
From Zhongguo Yaofang (2016), 27(5), 616-618
 
Determination of aciclovir and ganciclovir in human plasma by liquid chromatography-​spectrofluorimetric detection and stability studies in blood samples
By Perrottet, N.; Beguin, A.; Meylan, P.; Pascual, M.; Manuel, O.; Buclin, T.; Biollaz, J.; Decosterd, L. A.
From Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences (2007), 852(1-2), 420-429
 

Aciclovir EP Impurity J is chemically 9,9′-[Ethane-1,2-diylbis(oxymethylene)]bis(2-amino-1,9-dihydro-6H-purin-6-one) (as per EP) ; 1,2-Bis[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethane (as per USP). It is also known as Acyclovir 9,9'-Diguanyl analog (USP) ; O-[(Guanin-9-yl)methyl] Acyclovir. Aciclovir EP Impurity J is supplied with detailed characterization data compliant with regulatory guideline. Aciclovir EP Impurity J can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aciclovir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.