7-Ethyl-10-Hydroxy Camptothecin D4

SZ CAT No:	SZ-I010D01
CAS No	1309283-21-3
Mol.F.	C22H16D4N2O5
Mol.Wt.	396.4
Inv. Status	Custom Synthesis

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Chemical Name: (S)-4,11-Diethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione-5,10,12,12-d4

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CCC1=C(C([2H])([2H])N(C2=O)C3=C(C([C@](O)4CC)=C2COC4=O)[2H])C3=NC5=CC=C(O)C([2H])=C15

RP-HPLC method development and validation for the simultaneous estimation of Irinotecan hydrochloride and Capecitabine in Active Pharmaceutical Ingredients (APIs)
By Vijaya Jyothi, M.; Bhargav, E.; Keerthana, B.; Varalakshmi, Devi K.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2018), 9(1), 63-67

Method development, validation and forced degradation studies of Irinotecan in bulk and pharmaceutical dosage form
By Swathi, Koduru; Farooqui, Tahmeena; Muntaha, Sidra Tul; Ayesha, Syeda Amtul; Shama, Syeda; Siddiqui, Sarah Imam
From World Journal of Pharmacy and Pharmaceutical Sciences (2018), 7(8), 996-1009

7-Ethyl-10-Hydroxy Camptothecin D4 is chemically (S)-4,11-Diethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione-5,10,12,12-d4. 7-Ethyl-10-Hydroxy Camptothecin D4 is supplied with detailed characterization data compliant with regulatory guideline. 7-Ethyl-10-Hydroxy Camptothecin D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

7-Ethyl-10-Hydroxy Camptothecin D4

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