Dichlorothiophene Carboxylic Acid

SZ CAT No:	SZ-R017072
CAS No	89166-94-9
Mol.F.	C5H2Cl2O2S
Mol.Wt.	197.0
Inv. Status	Custom Synthesis

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Chemical Name: 3,5-dichlorothiophene-2-carboxylic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=CC(Cl)=C(C(O)=O)S1

Development and validation of stability indicating UPLC method for the determination of Rivaroxaban in bulk and finished products and identification of degradation products by LCMS
By Ali, Syed Mastan; Ramachandran, D.
From Journal of Applicable Chemistry (Lumami, India) (2021), 10(3), 291-301

Validated LC-MS/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance
By Korlakunta, Vijaya Gouri; Dasari, Vijaya Bharathi; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2020), 7(8), 492-500

Development of a stability-indicating HPLC method and a dissolution test for rivaroxaban dosage forms
By Souri, Effat; Mottaghi, Siavash; Zargarpoor, Mohammad; Ahmadkhaniha, Reza; Jalalizadeh, Hassan
From Acta Chromatographica (2016), 28(3), 347-361

Dichlorothiophene Carboxylic Acid is chemically 3,5-dichlorothiophene-2-carboxylic acid. Dichlorothiophene Carboxylic Acid is supplied with detailed characterization data compliant with regulatory guideline. Dichlorothiophene Carboxylic Acid can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Rivaroxaban.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Rivaroxaban

SZ CAT No:	: SZ-R017001
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Mol.F.	: C19H18ClN3O5S
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Rivaroxaban EP Impurity B

SZ CAT No:	: SZ-R017002
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Rivaroxaban Aminomethyl Base Impurity

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Mol.F.	: C14H17N3O4
Mol.Wt.	: 291.3
Inv. Status	: In Stock
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Rivaroxaban Aminomethyl HCl Impurity

SZ CAT No:	: SZ-R017004
CAS No	: 898543-06-1
Mol.F.	: C14H17N3O4 : HCl
Mol.Wt.	: 291.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 446292-10-0 (free base) ; 1251952-81-4 (HBr salt) ; 1251952-66-5 (Sulfate salt)

Rivaroxaban CMTCA Impurity

SZ CAT No:	: SZ-R017005
CAS No	: 97799-98-9
Mol.F.	: C6H6CINOS
Mol.Wt.	: 175.6
Inv. Status	: In Stock

Rivaroxaban EP Impurity F

SZ CAT No:	: SZ-R017006
CAS No	: 24065-33-6
Mol.F.	: C5H3ClO2S
Mol.Wt.	: 162.6
Inv. Status	: In Stock
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Rivaroxaban Descarbonyl Impurity

SZ CAT No:	: SZ-R017007
CAS No	: 721401-53-2
Mol.F.	: C18H20CIN3O4S
Mol.Wt.	: 409.9
Inv. Status	: In Stock

Rivaroxaban EP Impurity E

SZ CAT No:	: SZ-R017008
CAS No	: 1415566-28-7
Mol.F.	: C19H19N3O5S
Mol.Wt.	: 401.4
Inv. Status	: In Stock

Rivaroxaban Diol

SZ CAT No:	: SZ-R017009
CAS No	: 1160170-00-2
Mol.F.	: C19H20ClN3O6S
Mol.Wt.	: 453.9
Inv. Status	: Out of Stock, Custom Synthesis

Rivaroxaban N-Methylphthalimide Impurity

SZ CAT No:	: SZ-R017010
CAS No	: 550-44-7
Mol.F.	: C9H7NO2
Mol.Wt.	: 161.2
Inv. Status	: In Stock

Rivaroxaban Open-Ring Acid Impurity (HCl salt)

SZ CAT No:	: SZ-R017011
CAS No	: 931117-61-2
Mol.F.	: C19H20ClN3O6S : HCl
Mol.Wt.	: 453.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 931204-39-6 (free base)

Rivaroxaban EP Impurity J

SZ CAT No:	: SZ-R017012
CAS No	: 1632463-24-1
Mol.F.	: C38H36CI2N6O10S2
Mol.Wt.	: 871.8
Inv. Status	: In Stock

Rivaroxaban Open-Ring N-Methyl Impurity

SZ CAT No:	: SZ-R017013
CAS No	: 1807455-76-0
Mol.F.	: C25H24Cl2N4O6S2
Mol.Wt.	: 611.5
Inv. Status	: In Stock

Rivaroxaban Phthalamide Dimer

SZ CAT No:	: SZ-R017014
CAS No	: 1365267-36-2
Mol.F.	: C36H36N6O10
Mol.Wt.	: 712.7
Inv. Status	: In Stock

Rivaroxaban Phthalimido Descarbonyl Impurity (R-Isomer)

SZ CAT No:	: SZ-R017015
CAS No	: 446292-07-5
Mol.F.	: C21H21N3O5
Mol.Wt.	: 395.4
Inv. Status	: In Stock

Rivaroxaban EP Impurity G

SZ CAT No:	: SZ-R017016
CAS No	: 446292-08-6
Mol.F.	: C22H19N3O6
Mol.Wt.	: 421.4
Inv. Status	: In Stock

Rivaroxaban EP Impurity A

SZ CAT No:	: SZ-R017017
CAS No	: 865479-71-6
Mol.F.	: C19H18CIN3O5S
Mol.Wt.	: 435.9
Inv. Status	: In Stock

Rivaroxaban EP Impurity D

SZ CAT No:	: SZ-R017018
CAS No	: 1365267-35-1
Mol.F.	: C29H32N6O9
Mol.Wt.	: 608.6
Inv. Status	: In Stock

Rivaroxaban 3-Hydroxy Metabolite

SZ CAT No:	: SZ-R017019
CAS No	: 1160169-97-0
Mol.F.	: C19H18ClN3O6S
Mol.Wt.	: 451.9
Inv. Status	: Custom Synthesis

Rivaroxaban 4-Hydroxy Metabolite

SZ CAT No:	: SZ-R017020
CAS No	: 1161719-51-2
Mol.F.	: C19H18ClN3O6S
Mol.Wt.	: 451.9
Inv. Status	: Custom Synthesis

Rivaroxaban Methyl Ester Impurity

SZ CAT No:	: SZ-R017021
CAS No	: NA
Mol.F.	: C16H19N3O6
Mol.Wt.	: 349.3
Inv. Status	: In Stock

Rivaroxaban Degradate -1

SZ CAT No:	: SZ-R017022
CAS No	: NA
Mol.F.	: C13H19N3O2 : HCl
Mol.Wt.	: 249.3 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1816946-19-6 (free base)

Rivaroxaban Oxo Amine Amide Impurity

SZ CAT No:	: SZ-R017023
CAS No	: 1838139-24-4
Mol.F.	: C19H18ClN3O5S
Mol.Wt.	: 435.9
Inv. Status	: In Stock

Aminophenylmorpholinone

SZ CAT No:	: SZ-R017024
CAS No	: 438056-69-0
Mol.F.	: C10H12N2O2
Mol.Wt.	: 192.2
Inv. Status	: In Stock
Rel. CAS No	: 1640884-60-1 (HCl salt)

Rivaroxaban Impurity E

SZ CAT No:	: SZ-R017025
CAS No	: 1252018-10-2
Mol.F.	: C13H17ClN2O3
Mol.Wt.	: 284.7
Inv. Status	: In Stock

Rivaroxaban Impurity 1

SZ CAT No:	: SZ-R017026
CAS No	: 530-62-1
Mol.F.	: C7H6N4O
Mol.Wt.	: 162.2
Inv. Status	: In Stock

Rivaroxaban Impurity 2

SZ CAT No:	: SZ-R017027
CAS No	: 85-41-6
Mol.F.	: C8H5NO2
Mol.Wt.	: 147.2
Inv. Status	: In Stock
Rel. CAS No	: 33081-78-6 (Na salt) ; 1074-82-4 (K salt)

Rivaroxaban Impurity 3

SZ CAT No:	: SZ-R017028
CAS No	: 1074-82-4
Mol.F.	: C8H4NO2 : K
Mol.Wt.	: 146.1 : 39.1
Inv. Status	: In Stock
Rel. CAS No	: 85-41-6 (free base) ; 33081-78-6 (Na salt)

Rivaroxaban Impurity 4

SZ CAT No:	: SZ-R017029
CAS No	: 1445-69-8
Mol.F.	: C8H6N2O2
Mol.Wt.	: 162.2
Inv. Status	: In Stock
Rel. CAS No	: 20116-60-3 (Na salt) ; 477282-81-8 (K salt)

Rivaroxaban Impurity 6

SZ CAT No:	: SZ-R017031
CAS No	: 51594-55-9
Mol.F.	: C3H5ClO
Mol.Wt.	: 92.5
Inv. Status	: In Stock

Rivaroxaban Impurity 7

SZ CAT No:	: SZ-R017032
CAS No	: 124-63-0
Mol.F.	: CH3ClO2S
Mol.Wt.	: 114.5
Inv. Status	: In Stock
Rel. CAS No	: 1892578-86-7 (HCl salt)

Rivaroxaban Impurity 8

SZ CAT No:	: SZ-R017033
CAS No	: 96-43-5
Mol.F.	: C4H3ClS
Mol.Wt.	: 118.6
Inv. Status	: In Stock

Dichlorothienoic Acid

SZ CAT No:	: SZ-R017034
CAS No	: 31166-29-7
Mol.F.	: C5H2Cl2O2S
Mol.Wt.	: 197.0
Inv. Status	: In Stock

Rivaroxaban Impurity 11

SZ CAT No:	: SZ-R017035
CAS No	: 616-47-7
Mol.F.	: C4H6N2
Mol.Wt.	: 82.1
Inv. Status	: In Stock
Rel. CAS No	: 35487-17-3 (HCl salt) ; 101023-58-9 (HBr salt) ; 681281-87-8 (Sulfate salt)

Rivaroxaban Impurity 12

SZ CAT No:	: SZ-R017036
CAS No	: 527-72-0
Mol.F.	: C5H4O2S
Mol.Wt.	: 128.2
Inv. Status	: In Stock
Rel. CAS No	: 25112-68-9 (Na salt) ; 33311-43-2 (K salt) ; 150898-93-4 (HCl salt)

Rivaroxaban Impurity 14

SZ CAT No:	: SZ-R017037
CAS No	: 2437650-74-1
Mol.F.	: C10H12N2O2 : HCl
Mol.Wt.	: 192.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1082588-73-5 (Free base)

Rivaroxaban Impurity 15

SZ CAT No:	: SZ-R017038
CAS No	: 446292-04-2
Mol.F.	: C10H10N2O4
Mol.Wt.	: 222.2
Inv. Status	: In Stock

Rivaroxaban Impurity 16

SZ CAT No:	: SZ-R017039
CAS No	: NA
Mol.F.	: C16H22Cl2N2O4 : HCl
Mol.Wt.	: 377.3 : 36.5
Inv. Status	: In Stock

Rivaroxaban Impurity 18

SZ CAT No:	: SZ-R017041
CAS No	: 2206826-69-7
Mol.F.	: C15H19N3O6S
Mol.Wt.	: 369.4
Inv. Status	: In Stock

Rivaroxaban Amide Dimer

SZ CAT No:	: SZ-R017042
CAS No	: 1838133-00-8
Mol.F.	: C23H21Cl2N3O5S2
Mol.Wt.	: 554.5
Inv. Status	: Limited Stock

Rivaroxaban Impurity 20

SZ CAT No:	: SZ-R017043
CAS No	: 6310-09-4
Mol.F.	: C6H5ClOS
Mol.Wt.	: 160.6
Inv. Status	: In Stock

Rivaroxaban Impurity 21

SZ CAT No:	: SZ-R017044
CAS No	: 1328136-38-4
Mol.F.	: C11H14N2O4S
Mol.Wt.	: 270.3
Inv. Status	: In Stock

Rivaroxaban Impurity 22

SZ CAT No:	: SZ-R017045
CAS No	: 19532-98-0
Mol.F.	: C10H12N2O2
Mol.Wt.	: 192.2
Inv. Status	: In Stock

Rivaroxaban Impurity 23

SZ CAT No:	: SZ-R017046
CAS No	: NA
Mol.F.	: C18H22ClN3O5S : HCl
Mol.Wt.	: 427.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2807707-89-5 (free base)

(S)-Glycidyl Phthalimide

SZ CAT No:	: SZ-R017047
CAS No	: 161596-47-0
Mol.F.	: C11H9NO3
Mol.Wt.	: 203.2
Inv. Status	: In Stock

Rivaroxaban-D4

SZ CAT No:	: SZ-R017D01
CAS No	: 1132681-38-9
Mol.F.	: C19H14D4ClN3O5S
Mol.Wt.	: 439.9
Inv. Status	: In Stock

Rivaroxaban Dioxazolidine impurity

SZ CAT No:	: SZ-R017048
CAS No	: 2809182-22-5
Mol.F.	: C28H31N5O8
Mol.Wt.	: 565.6
Inv. Status	: Custom Synthesis

Rivaroxaban Impurity 17

SZ CAT No:	: SZ-R017040
CAS No	: NA
Mol.F.	: C28H31N5O8
Mol.Wt.	: 565.6
Inv. Status	: In Stock

Rivaroxaban Amide impurity

SZ CAT No:	: SZ-R017050
CAS No	: 482305-98-6
Mol.F.	: C18H20N3O4ClS
Mol.Wt.	: 409.9
Inv. Status	: In Stock

Rivaroxaban Impurity H

SZ CAT No:	: SZ-R017051
CAS No	: 1265682-11-8
Mol.F.	: C14H17ClO2S
Mol.Wt.	: 291.3
Inv. Status	: Custom Synthesis

Rivaroxaban Impurity 25

SZ CAT No:	: SZ-R017052
CAS No	: NA
Mol.F.	: C28H31N5O8
Mol.Wt.	: 565.6
Inv. Status	: In Stock

Rivaroxaban EP Impurity I

SZ CAT No:	: SZ-R017053
CAS No	: 1151893-81-0
Mol.F.	: C24H21Cl2N3O7S2
Mol.Wt.	: 598.5
Inv. Status	: In Stock

Rivaroxaban EP Impurity H

SZ CAT No:	: SZ-R017054
CAS No	: 1770812-37-7
Mol.F.	: C19H17Cl2N3O5S
Mol.Wt.	: 470.3
Inv. Status	: In Stock

Morpholine-3-one

SZ CAT No:	: SZ-R017055
CAS No	: 109-11-5
Mol.F.	: C4H7NO2
Mol.Wt.	: 101.1
Inv. Status	: Out of Stock
Rel. CAS No	: 859448-52-5 (HBr salt)

Rivaroxaban Impurity 28

SZ CAT No:	: SZ-R017056
CAS No	: 2137914-93-1
Mol.F.	: C18H14N2O4
Mol.Wt.	: 322.3
Inv. Status	: In Stock

Rivaroxaban N-methylphthalamido Analog

SZ CAT No:	: SZ-R017057
CAS No	: 2206360-74-7
Mol.F.	: C23H24N4O6
Mol.Wt.	: 452.5
Inv. Status	: In Stock

Rivaroxaban Impurity 30

SZ CAT No:	: SZ-R017058
CAS No	: 6843-36-3
Mol.F.	: C9H9NO3
Mol.Wt.	: 179.2
Inv. Status	: In Stock

Rivaroxaban Impurity 31

SZ CAT No:	: SZ-R017059
CAS No	: 1365267-37-3
Mol.F.	: C22H21N3O7
Mol.Wt.	: 439.4
Inv. Status	: In Stock

Rivaroxaban Impurity 32

SZ CAT No:	: SZ-R017060
CAS No	: 956904-18-0
Mol.F.	: C10H10N2O3
Mol.Wt.	: 206.2
Inv. Status	: Custom Synthesis

Rivaroxaban Impurity 33

SZ CAT No:	: SZ-R017061
CAS No	: 2071690-76-9
Mol.F.	: C5HCl3OS
Mol.Wt.	: 215.5
Inv. Status	: Custom Synthesis

Rivaroxaban Impurity 34

SZ CAT No:	: SZ-R017062
CAS No	: 1446470-85-4
Mol.F.	: C5HCl3OS
Mol.Wt.	: 215.5
Inv. Status	: Custom Synthesis

Rivaroxaban Impurity 35

SZ CAT No:	: SZ-R017063
CAS No	: 89283-13-6
Mol.F.	: C5HCl3OS
Mol.Wt.	: 215.5
Inv. Status	: Custom Synthesis

4-(3-Aminophenyl)-3-morpholinone

SZ CAT No:	: SZ-R017064
CAS No	: 1082495-22-4
Mol.F.	: C10H12N2O2
Mol.Wt.	: 192.2
Inv. Status	: In Stock

Rivaroxaban Impurity 36

SZ CAT No:	: SZ-R017065
CAS No	: NA
Mol.F.	: C27H22ClN3O8S
Mol.Wt.	: 584.0
Inv. Status	: In Stock

Rivaroxaban Impurity 37

SZ CAT No:	: SZ-R017066
CAS No	: 811450-82-5
Mol.F.	: C10H11ClN2O4
Mol.Wt.	: 258.7
Inv. Status	: In Stock

Rivaroxaban Impurity 38

SZ CAT No:	: SZ-R017067
CAS No	: 1082588-73-5
Mol.F.	: C10H12N2O2
Mol.Wt.	: 192.2
Inv. Status	: In Stock
Rel. CAS No	: 2437650-74-1 (HCl salt)

N-Glycidyl Phthalimide

SZ CAT No:	: SZ-R017068
CAS No	: 5455-98-1
Mol.F.	: C11H9NO3
Mol.Wt.	: 203.2
Inv. Status	: In Stock

3-chloro Rivaroxaban

SZ CAT No:	: SZ-R017069
CAS No	: 1855920-54-5
Mol.F.	: C19H18ClN3O5S
Mol.Wt.	: 435.9
Inv. Status	: In Stock

3-Chlorothiophene-2-carboxylic acid

SZ CAT No:	: SZ-R017070
CAS No	: 59337-89-2
Mol.F.	: C5H3ClO2S
Mol.Wt.	: 162.6
Inv. Status	: In Stock, 3-4 days for Dispatch
Rel. CAS No	: 105734-84-7 (K salt)

3,4-dichlorothiophene-2-carboxylic acid

SZ CAT No:	: SZ-R017071
CAS No	: 61209-02-7
Mol.F.	: C5H2Cl2O2S
Mol.Wt.	: 197.0
Inv. Status	: Custom Synthesis