Timolol EP Impurity E (TFA Salt)

Timolol EP Impurity E (TFA Salt) is chemically (2Z)-4-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid with 2,2,2-trifluoroacetic acid (1:1) (as per EP) ; (S,Z)-4-({1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl}oxy)-4-oxobut-2-enoic acid with 2,2,2-trifluoroacetic acid (1:1) (as per USP). It is also known as Timolol USP Related Compound E. Timolol EP Impurity E (TFA Salt) is supplied with detailed characterization data compliant with regulatory guideline. Timolol EP Impurity E (TFA Salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Timolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.