Palbociclib Oxidation Impurity

New stability-​indicating liquid chromatographic method for determination of palbociclib (an anti-​breast cancer drug)
By Kallepalli, Pramadvara; Annapurna, Mukthinuthalapati Mathrusri
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S270-S275
 
Optimization and validation of RP-​HPLC method for simultaneous estimation of palbociclib and letrozole
By Dange, Yuvraj; Bhinge, Somnath; Salunkhe, Vijay
From Toxicology Mechanisms and Methods (2018), 28(3), 187-194

Palbociclib Oxidation Impurity is chemically (6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)glycine. It is also known as Palbociclib N-Acetic Acid. Palbociclib Oxidation Impurity is supplied with detailed characterization data compliant with regulatory guideline. Palbociclib Oxidation Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Palbociclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.