Palbociclib Impurity 4

New stability-​indicating liquid chromatographic method for determination of palbociclib (an anti-​breast cancer drug)
By Kallepalli, Pramadvara; Annapurna, Mukthinuthalapati Mathrusri
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S270-S275
 
Optimization and validation of RP-​HPLC method for simultaneous estimation of palbociclib and letrozole
By Dange, Yuvraj; Bhinge, Somnath; Salunkhe, Vijay
From Toxicology Mechanisms and Methods (2018), 28(3), 187-194

Palbociclib Impurity 4 is chemically Pyrido[2,​3-​d]​pyrimidin-​7(8H)​-​one, 8-​cyclopentyl-​6-​(1-​hydroxyethyl)​-​5-​methyl-​2-​[[5-​(1-​piperazinyl)​-​2-​pyridinyl]​amino]​-. Palbociclib Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Palbociclib Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Palbociclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.