Estradiol D4

Validated RP-HPLC method for the determination of estradiol valerate in bulk and pharmaceutical formulations
M. Madhu1 *, Satyadev T. N. V. S. S.1 , G. Hephzibah1 and T. V. Reddy
Der Pharmacia Lettre, 2016, 8 (4):50-61
 
Determination of estradiol and its degradation products by liquid chromatography
Lucie Havlíková, Lucie Nováková, Ludmila Matysová, Jan Sícha
Journal of Chromatography A 1119(1-2):216-23
 
Determination of Related Substances in Estradiol Valerate Tablet by Use of HPLC Method
Du, Biying
Current Pharmaceutical Analysis, Volume 14, Number 5, 2018, pp. 513-518(6)

Estradiol D4 is chemically (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-2,4,16,16-d4-3,17-diol. Estradiol D4 is supplied with detailed characterization data compliant with regulatory guideline. Estradiol D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Estradiol Valerate.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.