Chlortalidone EP Impurity D

Investigation of novel supersaturating drug delivery systems of chlorthalidone: The use of polymer-surfactant complex as an effective carrier in solid dispersions
Maria TerezinhaFrançaRafaelNicolay PereiraManoelaKlüppel RiekesJulianaMunari Oliveira PintoHellen KarineStulzer
European Journal of Pharmaceutical Sciences Volume 111, 1 January 2018, Pages 142-152
 
A Validated RP-HPLC Stability Method for the Estimation of Chlorthalidone and Its Process-Related Impurities in an API and Tablet Formulation
Chaitali Kharat,1 Vaishali A. Shirsat , 1 Yogita M. Kodgule,2 and Mandar Kodgule
Hindawi International Journal of Analytical Chemistry Volume 2020, Article ID 3593805, 11 pages
 
Stability-Indicating RP-UPLC Method for Simultaneous Determination of Azilsartan Medoxomil and Chlorthalidone in Tablets in the Presence of Its Degradation Products
Lobna A Hussein, Nancy N Magdy, Michael A Ibrahim
Journal of Chromatographic Science, Volume 57, Issue 3, March 2019, Pages 213–219

Chlortalidone EP Impurity D is chemically 2-Chloro-5-[(1RS)-1-ethoxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl]benzene-1-sulfonamide (as per EP). It is also known as Chlorthalidone Ethyl Ether ; O-Ethyl Chlorthalidone . Chlortalidone EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Chlortalidone EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Chlortalidone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.