Buspirone EP Impurity B

Development and validation of a high-performance liquid chromatographic method for the determination of buspirone in pharmaceutical preparations
M. Zaxariou, I. Panderi
Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 41–50
 
Liquid Chromatographic Method for the Analysis of Buspirone HCl and Its Potential Impurities
Murat Kartal, Alaa Khedr, Adel Sakr
Journal of Chromatographic Science, Volume 38, Issue 4, April 2000, Pages 151–156
 
Hybrid triple quadrupole-linear ion trap mass spectrometry in fragmentation mechanism studies: application to structure elucidation of buspirone and one of its metabolites
Mei-Yi Zhang,1∗ Nadia Pace,2 Edward H. Kerns,1 Teresa Kleintop,1 Natasha Kagan1 and Takeo Sakuma2
Journal of mass spectrometry j. Mass Spectrom. 2005; 40: 1017–1029

Buspirone EP Impurity B is chemically 8-(Pyrimidin-2-yl)-8-aza-5-azoniaspiro[4.5]decane (as per EP & USP). It is also known as Buspirone Spiroammonium Salt Impurity (USP) . Buspirone EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Buspirone EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Buspirone .

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.