Didesfluoro Nebivolol

N° de SZ CAT:	SZ-N020048
Número CAS	129101-33-3
Mol.F.	C22H27NO4
Peso Molecular	369.5
Status de Fatura	In Stock
Rel. CAS No	1698011-22-1 (HCl salt)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: α,α’-[Iminobis(methylene)]bis[3,4-dihydro-2H-1-benzopyran-2-methanol ; 2,2’-Azanediylbis(1-chroman-2-yl)ethanol

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: [H][C@@]1(OC2=CC=CC=C2CC1)[C@@H](O)CNC[C@H](O)[C@]3(CCC(C=CC=C4)=C4O3)[H]

Development and validation of a stability-indicating reverse phase ultra performance liquid chromatographic method for the estimation of nebivolol impurities in active pharmaceutical ingredients and pharmaceutical formulation
Veera Raghava Raju Thummala, Mohana Krishna Lanka
Se Pu. 2015 Oct;33(10):1051-8.

Stability-Indicating RP-UPLC Method Development and Validation for the Process Related Impurities of Nebivolol and Structural Characterization of Its Forced Degradation Products by LC-MS/MS
Prasad Kancherla1* , Pallavi Alegete1 , Srinivas Keesari2 , Bhavyasri Khagga1 , Sridhar Siddiraju3 , Mukkanti Khagga1 and Parthasarathi Das
British Journal of Pharmaceutical Research 14(6): 1-13, 2016

Liquid chromatographic impurity profiling of Nebivolol Hydrochloride from bulk drug
Sachin Uttamrao Kokil*1 , Manish Sudesh Bhatia
Scholars Research Library Der Pharma Chemica, 2009, 1(2): 177-187

A Sensitive and Selective GC-MS Analysis of Process Related Genotoxic Impurities of Nebivolol Hydrochloride
Vijaya Lakshmi Maddala, K. Venugopal, P.C. Ray, K.M.V.N. Rao

Didesfluoro Nebivolol is chemically α,α’-[Iminobis(methylene)]bis[3,4-dihydro-2H-1-benzopyran-2-methanol ; 2,2’-Azanediylbis(1-chroman-2-yl)ethanol. Didesfluoro Nebivolol is supplied with detailed characterization data compliant with regulatory guideline. Didesfluoro Nebivolol can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

products.relatedproducts

Nebivolol Impurity 11

N° de SZ CAT:	: SZ-N020023
Número CAS	: 920275-19-0
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: Out of Stock

Nebivolol Impurity 12

N° de SZ CAT:	: SZ-N020024
Número CAS	: 119365-29-6
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.4
Status de Fatura	: In Stock

Nebivolol Impurity 13

N° de SZ CAT:	: SZ-N020025
Número CAS	: NA
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.5 : 36.5
Status de Fatura	: Out of Stock

Nebivolol HCl

N° de SZ CAT:	: SZ-N020001
Número CAS	: 152520-56-4
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

Levonebivolol

N° de SZ CAT:	: SZ-N020002
Número CAS	: 118457-16-2
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.4
Status de Fatura	: In Stock

Nebivolol Impurity 4 (SS,RS) Hydrochloride

N° de SZ CAT:	: SZ-N020003
Número CAS	: 920299-27-0
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

Nebivolol USP Related Compound D

N° de SZ CAT:	: SZ-N020004
Número CAS	: 793669-26-8
Mol.F.	: C11H11FO2
Peso Molecular	: 194.2
Status de Fatura	: In Stock

Nebivolol Impurity 6

N° de SZ CAT:	: SZ-N020006
Número CAS	: 876514-31-7
Mol.F.	: C11H11FO2
Peso Molecular	: 194.2
Status de Fatura	: In Stock

Nebivolol USP Related Compound E

N° de SZ CAT:	: SZ-N020007
Número CAS	: NA
Mol.F.	: C22H26FNO4 : HCl
Peso Molecular	: 387.5 : 36.5
Status de Fatura	: In Stock

Nebivolol O-Beta-D-Glucuronide

N° de SZ CAT:	: SZ-N020008
Número CAS	: NA
Mol.F.	: C28H33F2NO10
Peso Molecular	: 581.6
Status de Fatura	: Custom Synthesis

4-Hydroxy Nebivolol

N° de SZ CAT:	: SZ-N020009
Número CAS	: 178383-76-1
Mol.F.	: C22H25F2NO5
Peso Molecular	: 421.4
Status de Fatura	: Custom Synthesis

Nebivolol EP Impurity B (TFA salt)

N° de SZ CAT:	: SZ-N020010
Número CAS	: NA
Mol.F.	: C22H25F2NO4 : C2HF3O2
Peso Molecular	: 405.4 : 114.0
Status de Fatura	: Limited Stock

Nebivolol Impurity 1

N° de SZ CAT:	: SZ-N020011
Número CAS	: 1346562-34-2
Mol.F.	: C12H17NO2
Peso Molecular	: 207.3
Status de Fatura	: In Stock

Nebivolol Impurity 2

N° de SZ CAT:	: SZ-N020012
Número CAS	: NA
Mol.F.	: C22H21F2NO4 : HCl
Peso Molecular	: 401.4 : 36.5
Status de Fatura	: Custom Synthesis

Nebivolol Impurity 3 (RRSS) (HCl)

N° de SZ CAT:	: SZ-N020013
Número CAS	: NA
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

Nebivolol Impurity 5 (RRSR) (HCl)

N° de SZ CAT:	: SZ-N020015
Número CAS	: 920275-20-3
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

Nebivolol Impurity 7

N° de SZ CAT:	: SZ-N020017
Número CAS	: 1029684-20-5
Mol.F.	: C18H20FNO2
Peso Molecular	: 301.4
Status de Fatura	: In Stock

Nebivolol Impurity 8

N° de SZ CAT:	: SZ-N020018
Número CAS	: 129050-27-7
Mol.F.	: C18H20FNO2
Peso Molecular	: 301.4
Status de Fatura	: In Stock

Nebivolol Impurity 9

N° de SZ CAT:	: SZ-N020019
Número CAS	: 99199-91-4
Mol.F.	: C18H20FNO2
Peso Molecular	: 301.4
Status de Fatura	: In Stock

Nebivolol Impurity 10 (SS)

N° de SZ CAT:	: SZ-N020020
Número CAS	: NA
Mol.F.	: C12H16FNO2
Peso Molecular	: 225.3
Status de Fatura	: Custom Synthesis

Nebivolol Impurity 14 (RR)

N° de SZ CAT:	: SZ-N020026
Número CAS	: NA
Mol.F.	: C12H16FNO2
Peso Molecular	: 225.3
Status de Fatura	: Custom Synthesis

Nebivolol Impurity 15 (RS)

N° de SZ CAT:	: SZ-N020027
Número CAS	: NA
Mol.F.	: C12H16FNO2
Peso Molecular	: 225.3
Status de Fatura	: Custom Synthesis

Nebivolol Impurity 16 (SR)

N° de SZ CAT:	: SZ-N020028
Número CAS	: 1447800-92-1
Mol.F.	: C12H16FNO2
Peso Molecular	: 225.3
Status de Fatura	: Custom Synthesis

Nebivolol Impurity 17 (SS,RR)

N° de SZ CAT:	: SZ-N020029
Número CAS	: 119365-30-9
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.5
Status de Fatura	: In Stock

Nebivolol Impurity 20 (SS,SS) (HCl)

N° de SZ CAT:	: SZ-N020032
Número CAS	: 920275-27-0
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

D-Nebivolol

N° de SZ CAT:	: SZ-N020033
Número CAS	: 118457-15-1
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.5
Status de Fatura	: In Stock

Nebivolol Related Compound B

N° de SZ CAT:	: SZ-N020035
Número CAS	: NA
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.5 : 36.5
Status de Fatura	: In Stock

Nebivolol Related Compound A

N° de SZ CAT:	: SZ-N020036
Número CAS	: NA
Mol.F.	: C22H25F2NO4 : HCl
Peso Molecular	: 405.4 : 36.5
Status de Fatura	: In Stock

Nebivolol EP Impurity C

N° de SZ CAT:	: SZ-N020038
Número CAS	: 929706-85-4
Mol.F.	: C29H31F2NO4
Peso Molecular	: 495.6
Status de Fatura	: In Stock

Nebivolol Impurity 27

N° de SZ CAT:	: SZ-N020039
Número CAS	: 129050-23-3
Mol.F.	: C11H11FO2
Peso Molecular	: 194.2
Status de Fatura	: In Stock

Nebivolol Impurity 29

N° de SZ CAT:	: SZ-N020041
Número CAS	: 197706-50-6
Mol.F.	: C11H11FO2
Peso Molecular	: 194.2
Status de Fatura	: In Stock

Nebivolol Impurity 30

N° de SZ CAT:	: SZ-N020042
Número CAS	: 129050-26-6
Mol.F.	: C11H11FO2
Peso Molecular	: 194.2
Status de Fatura	: In Stock

Nebivolol Impurity 31(RRSS)

N° de SZ CAT:	: SZ-N020043
Número CAS	: 119365-23-0
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.4
Status de Fatura	: In Stock

Nebivolol Impurity 32(SRRS)

N° de SZ CAT:	: SZ-N020044
Número CAS	: 119365-24-1
Mol.F.	: C22H25F2NO4
Peso Molecular	: 405.4
Status de Fatura	: In Stock

Nebivolol Impurity 33

N° de SZ CAT:	: SZ-N020045
Número CAS	: 943126-72-5
Mol.F.	: C11H10ClFO2
Peso Molecular	: 228.6
Status de Fatura	: In Stock

Nebivolol Impurity 34 (RSRR+RRRR)

N° de SZ CAT:	: SZ-N020046
Número CAS	: NA
Mol.F.	: C44H50F4N2O8
Peso Molecular	: 810.9
Status de Fatura	: Out of Stock, Custom Synthesis

Nebivolol Impurity 35

N° de SZ CAT:	: SZ-N020047
Número CAS	: NA
Mol.F.	: C88H100F8N4O16 : HCl
Peso Molecular	: 1621.8 : 36.5
Status de Fatura	: Out of Stock, Custom Synthesis