Abemaciclib Impurity 28

N° de SZ CAT:	SZ-A077038
Número CAS	NA
Mol.F.	C27H33FN8
Peso Molecular	488.6
Status de Fatura

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Nome Químico: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CC1=NC2=CC=C(C3=NC(NC4=NC=C(CN5CCN(CC)CC5)C=C4)=NC=C3F)C=C2N1C(C)C

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

Abemaciclib Impurity 28 is chemically N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine. Abemaciclib Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Abemaciclib Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Abemaciclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Abemaciclib Impurity 28

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