Abemaciclib

N° de SZ CAT:	SZ-A077001
Número CAS	1231929-97-7
Mol.F.	C27H32F2N8
Peso Molecular	506.6
Status de Fatura	In Stock
Rel. CAS No	2089320-70-5 (HCl salt) ; 1231930-82-7 (Methanesulfonic acid)
Shipping Condition	Ambient Temperature

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Nome Químico: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Sinônimo: Verzenio ; Verzenios

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CC(N1C2=CC(C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)=CC(F)=C2N=C1C)C

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

Abemaciclib is chemically N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine. It is also known as Verzenio ; Verzenios. Abemaciclib is supplied with detailed characterization data compliant with regulatory guideline. Abemaciclib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Abemaciclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Abemaciclib

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N° de SZ CAT:	: SZ-A077001
Número CAS	: 1231929-97-7
Mol.F.	: C27H32F2N8
Peso Molecular	: 506.6
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-A077D02
Número CAS	: 2088650-71-7
Mol.F.	: C27H22D10F2N8
Peso Molecular	: 516.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077D03
Número CAS	: 1809251-51-1
Mol.F.	: C27H27D5F2N8
Peso Molecular	: 511.6
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077D04
Número CAS	: NA
Mol.F.	: C27H25D7F2N8
Peso Molecular	: 513.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077D01
Número CAS	: 2088650-53-5
Mol.F.	: C27H24D8F2N8
Peso Molecular	: 514.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077003
Número CAS	: 1180132-17-5
Mol.F.	: C12H20N4
Peso Molecular	: 220.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077005
Número CAS	: 1231930-42-9
Mol.F.	: C15H13ClF2N4
Peso Molecular	: 322.7
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077006
Número CAS	: 414881-11-1
Mol.F.	: C12H19N3
Peso Molecular	: 205.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-A077007
Número CAS	: NA
Mol.F.	: C27H33FN8
Peso Molecular	: 488.6
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077008
Número CAS	: NA
Mol.F.	: C15H14F2N4
Peso Molecular	: 288.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-A077004
Número CAS	: 1231930-57-6
Mol.F.	: C25H28F2N8
Peso Molecular	: 478.6
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-A077002
Número CAS	: NA
Mol.F.	: C27H31F2N9O
Peso Molecular	: 535.6
Status de Fatura	: Inquire