Quetiapine Dipiperazine Monoether Impurity

SZ CAT No:	SZ-Q001036
CAS No	NA
Mol.F.	C27H37N5O2S : HCl
Mol.Wt.	495.7 : 36.5
Inv. Status	Custom Synthesis
Rel. CAS No	2206606-92-8 (free base)

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Chemical Name: 4-[2-[(4-Dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)]ethyl]-1-[(2-hydroxy ethoxyl)ethyl]-piperazine HCl

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: OCCOCCN1CCN(CCN2CCN(C3=NC4=CC=CC=C4SC5=CC=CC=C35)CC2)CC1.Cl

Identification and Characterization of Potential Impurities of Quetiapine Fumarate
Elżbieta U. Stolarczyk,Łukasz Kaczmarek,Kamil Eksanow,Marek Kubiszewski,Magdalena Glice &Andrzej Kutner
Pharmaceutical Development and Technology Volume 14, 2009 - Issue 1 Pages 29-39

An Improved and Single Pot Process for the Production of Quetiapine Hemifumarate Substantially Free from Potential Impurities
Navnath C. Niphade, Anil C. Mali, Bhushan S. Pandit, Kunal M. Jagtap, Sanjay A. Jadhav, Madhukar N. Jachak, and Vijayavitthal T. Mathad
Org. Process Res. Dev. 2009, 13, 4, 792–797

Stability indicating fast LC method for determination of quetiapine fumarate related substances in bulk and pharmaceutical formulation
R.Narendra Kumar, *G.Nageswara Rao, P.Y.Naidu
Der Pharmacia Lettre, 2011, 3(3): 457-469

Quetiapine Dipiperazine Monoether Impurity is chemically 4-[2-[(4-Dibenzo [b,f] [1,4]thiazepin-11-yl-1-piperazinyl)]ethyl]-1-[(2-hydroxy ethoxyl)ethyl]-piperazine HCl . Quetiapine Dipiperazine Monoether Impurity is supplied with detailed characterization data compliant with regulatory guideline. Quetiapine Dipiperazine Monoether Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Quetiapine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Quetiapine Hemifumarate

SZ CAT No:	: SZ-Q001001
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Mol.F.	: C21H25N3O2S : 1/2(C4H4O4)
Mol.Wt.	: 383.5 : 1/2(116.1)
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Quetiapine EP Impurity A

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Quetiapine EP Impurity B (dihydrochloride salt)

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Mol.F.	: C17H17N3S : 2(HCl)
Mol.Wt.	: 295.4 : 2(36.5)
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Quetiapine EP Impurity C

SZ CAT No:	: SZ-Q001004
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Mol.F.	: C40H42N6O3S2
Mol.Wt.	: 718.9
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Quetiapine EP Impurity D

SZ CAT No:	: SZ-Q001005
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Mol.F.	: C30H24N4S2 : HCl
Mol.Wt.	: 504.7 : 36.5
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Quetiapine EP Impurity E

SZ CAT No:	: SZ-Q001006
CAS No	: 1371638-05-9
Mol.F.	: C40H44N6O2S2
Mol.Wt.	: 704.9
Inv. Status	: In Stock

Quetiapine EP Impurity F

SZ CAT No:	: SZ-Q001007
CAS No	: 848814-27-7
Mol.F.	: C21H27N3O3S
Mol.Wt.	: 401.5
Inv. Status	: In Stock

Quetiapine EP Impurity G

SZ CAT No:	: SZ-Q001008
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Mol.F.	: C13H9NOS
Mol.Wt.	: 227.3
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Quetiapine EP Impurity H

SZ CAT No:	: SZ-Q001009
CAS No	: 1076199-40-0
Mol.F.	: C21H25N3O3S
Mol.Wt.	: 399.5
Inv. Status	: In Stock

Quetiapine EP Impurity I (2HCl Salt)

SZ CAT No:	: SZ-Q001010
CAS No	: 329218-14-6
Mol.F.	: C19H21N3OS : 2HCl
Mol.Wt.	: 339.5 : 2(36.5)
Inv. Status	: In Stock

Quetiapine EP Impurity J

SZ CAT No:	: SZ-Q001011
CAS No	: 1356906-17-6
Mol.F.	: C25H33N3O4S
Mol.Wt.	: 471.6
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Quetiapine EP Impurity K

SZ CAT No:	: SZ-Q001012
CAS No	: 1371638-10-6
Mol.F.	: C23H29N3O4S
Mol.Wt.	: 443.6
Inv. Status	: In Stock

Quetiapine EP Impurity L

SZ CAT No:	: SZ-Q001013
CAS No	: 1371638-11-7
Mol.F.	: C21H24ClN3O2S
Mol.Wt.	: 418
Inv. Status	: In Stock

Quetiapine EP Impurity N

SZ CAT No:	: SZ-Q001014
CAS No	: 1800291-86-4
Mol.F.	: C29H41N5O3S
Mol.Wt.	: 539.7
Inv. Status	: In Stock

Quetiapine EP Impurity O

SZ CAT No:	: SZ-Q001015
CAS No	: 844639-06-1
Mol.F.	: C40H39N3O2S
Mol.Wt.	: 625.8
Inv. Status	: In Stock

Quetiapine EP Impurity P HCl Salt

SZ CAT No:	: SZ-Q001016
CAS No	: NA
Mol.F.	: C19H21N3S : HCl
Mol.Wt.	: 323.5 : 36.5
Inv. Status	: In Stock

Quetiapine EP Impurity Q

SZ CAT No:	: SZ-Q001017
CAS No	: NA
Mol.F.	: C25H34N3O4S : I
Mol.Wt.	: 472.6 : 126.9
Inv. Status	: In Stock

Quetiapine Impurity R

SZ CAT No:	: SZ-Q001018
CAS No	: 2459-05-4
Mol.F.	: C6H8O4
Mol.Wt.	: 144.1
Inv. Status	: In Stock

Quetiapine EP Impurity S HCl Salt

SZ CAT No:	: SZ-Q001019
CAS No	: 329218-11-3
Mol.F.	: C21H25N3O3S : 2HCl
Mol.Wt.	: 399.5 : 2(36.5)
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Quetiapine EP Impurity T

SZ CAT No:	: SZ-Q001020
CAS No	: 5747-46-6
Mol.F.	: C17H16N2OS
Mol.Wt.	: 296.4
Inv. Status	: In Stock

Quetiapine EP Impurity U

SZ CAT No:	: SZ-Q001021
CAS No	: 5786-26-5
Mol.F.	: C13H10N2S
Mol.Wt.	: 226.3
Inv. Status	: In Stock

Quetiapine EP Impurity V

SZ CAT No:	: SZ-Q001022
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Mol.F.	: C21H25N3O2
Mol.Wt.	: 351.5
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Quetiapine EP Impurity W

SZ CAT No:	: SZ-Q001023
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Mol.F.	: C34H32N4O2S2
Mol.Wt.	: 592.8
Inv. Status	: In Stock

Quetiapine Ethyl Ether (Fumarate)

SZ CAT No:	: SZ-Q001024
CAS No	: 2470241-46-2
Mol.F.	: C23H29N3O2S : C4H4O4
Mol.Wt.	: 411.6 : 116.1
Inv. Status	: Custom Synthesis

Quetiapine HEEP Impurity

SZ CAT No:	: SZ-Q001025
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Mol.F.	: C8H18N2O2
Mol.Wt.	: 174.2
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Quetiapine Sulfone (HCl Salt)

SZ CAT No:	: SZ-Q001026
CAS No	: 329218-13-5
Mol.F.	: C21H25N3O4S : HCl
Mol.Wt.	: 415.5 : 36.5
Inv. Status	: Custom Synthesis

Quetiapine 7-Hydroxy Impurity

SZ CAT No:	: SZ-Q001027
CAS No	: NA
Mol.F.	: C21H25N3O3S : HCl
Mol.Wt.	: 399.5 : 36.5
Inv. Status	: Custom Synthesis

Quetiapine 7-Hydroxy Sulfoxide

SZ CAT No:	: SZ-Q001028
CAS No	: 1185170-04-0
Mol.F.	: C21H25N3O4S
Mol.Wt.	: 415.5
Inv. Status	: Custom Synthesis

Quetiapine Carboxylate Impurity

SZ CAT No:	: SZ-Q001029
CAS No	: 1011758-00-1
Mol.F.	: C22H25N3O4S
Mol.Wt.	: 427.5
Inv. Status	: Custom Synthesis

Quetiapine 11 Chloro Impurity

SZ CAT No:	: SZ-Q001030
CAS No	: 13745-86-3
Mol.F.	: C13H8ClNS
Mol.Wt.	: 245.7
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Quetiapine DBTC Sulfone

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Mol.F.	: C13H8ClNO2S
Mol.Wt.	: 277.7
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Quetiapine DBTO Sulfone

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Quetiapine DBTP 7-Hydroxy Metabolite

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Mol.F.	: C17H17N3OS
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Quetiapine DBTP N-Methyl Impurity

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CAS No	: 1977-09-9
Mol.F.	: C18H19N3S
Mol.Wt.	: 309.4
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Quetiapine Diether Alcohol (HCl salt)

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CAS No	: NA
Mol.F.	: C23H29N3O3S . HCl
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