Pazopanib Impurity 8

SZ CAT No:	SZ-P013033
CAS No	2795176-90-6
Mol.F.	C21H22N6O3S
Mol.Wt.	438.5
Inv. Status	Custom Synthesis

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Chemical Name: 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC1=CC=C(NC2=NC(N(C)C3=CC4=NN(C)C(C)=C4C=C3)=CC=N2)C=C1S(=O)(O)=O

Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S Kord
J Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.

Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu
Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102

Characterization of forced degradation products of pazopanib hydrochloride by UHPLC‐Q‐TOF/MS and in silico toxicity prediction
Prinesh N. Patel Pradipbhai D. Kalariya Mahesh Sharma Prabha Garg M. V. N Kumar Talluri S. Gananadhamu R. Srinivas
Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928

Development and validation of a stability indicating RP-HPLC method for the determination of Pazopanib in bulk drug and its pharmaceutical dosage form
Kishore Kumar Reddy Y, J. Raveendra Reddy and N. Devanna
J. Chem. Pharm. Res., 2015, 7(9):127-132

Validated RP-HPLC Method Development of Pazopanib in Bulk and its Pharmaceutical Dosage Form
Kiran Kumar Buralla, and Varadarajan Parthasarathy
Pharmaceutical Methods,2020,11,1,21-24.

Pazopanib Impurity 8 is chemically 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic acid. Pazopanib Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Pazopanib Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pazopanib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-P013001
CAS No	: 444731-52-6
Mol.F.	: C21H23N7O2S
Mol.Wt.	: 437.5
Inv. Status	: In Stock
Rel. CAS No	: 635702-64-6 (HCl salt) ; 1310529-66-8 (2HCl salt) ; 635702-65-7 (mesylate salt)

SZ CAT No:	: SZ-P013002
CAS No	: 80927-55-5
Mol.F.	: C4H3ClN2O
Mol.Wt.	: 130.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 39875-64-4 (Na salt)

SZ CAT No:	: SZ-P013005
CAS No	: 6274-28-8
Mol.F.	: C7H10N2O2S
Mol.Wt.	: 186.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 854635-95-3 (HCl salt)

SZ CAT No:	: SZ-P013006
CAS No	: 6269-91-6
Mol.F.	: C7H8N2O4S
Mol.Wt.	: 216.2
Inv. Status	: In Stock
Rel. CAS No	: 126148-19-4 (Na salt)

SZ CAT No:	: SZ-P013007
CAS No	: 55873-09-1
Mol.F.	: C4H3ClN2O
Mol.Wt.	: 130.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2818976-95-1 (HCl salt) ; 2913241-43-5 (Na salt)

Pazopanib Impurity 8

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SZ CAT No:	: SZ-P013003
CAS No	: 1226500-02-2
Mol.F.	: C26H23ClN10
Mol.Wt.	: 511.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013004
CAS No	: 1252927-44-8
Mol.F.	: C27H25ClN10
Mol.Wt.	: 525.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013008
CAS No	: 444731-73-1
Mol.F.	: C9H9N3O2
Mol.Wt.	: 191.2
Inv. Status	: In Stock
Rel. CAS No	: 1810075-92-3 (HCl salt)

SZ CAT No:	: SZ-P013009
CAS No	: 1313372-75-6
Mol.F.	: C8H7N3O2
Mol.Wt.	: 177.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013010
CAS No	: 1354224-47-7
Mol.F.	: C9H9N3O2
Mol.Wt.	: 191.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013011
CAS No	: 221681-92-1
Mol.F.	: C10H13N2
Mol.Wt.	: 161.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013012
CAS No	: 1414375-50-0
Mol.F.	: C21H23N7O3S
Mol.Wt.	: 453.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013013
CAS No	: 444731-74-2
Mol.F.	: C13H12ClN5
Mol.Wt.	: 273.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-P013014
CAS No	: 635702-60-2
Mol.F.	: C9H11N3 : HCl
Mol.Wt.	: 161.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 444731-72-0 (free base)

SZ CAT No:	: SZ-P013015
CAS No	: 444731-75-3
Mol.F.	: C14H14ClN5
Mol.Wt.	: 287.8
Inv. Status	: In Stock

SZ CAT No:	: SZ-P013016
CAS No	: 1296888-47-5
Mol.F.	: C15H17N5O
Mol.Wt.	: 283.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-P013017
CAS No	: 2518115-74-5
Mol.F.	: C21H23N7O2S : HCl
Mol.Wt.	: 437.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2369664-19-5 (free base)

SZ CAT No:	: SZ-P013018
CAS No	: 3934-20-1
Mol.F.	: C4H2Cl2N2
Mol.Wt.	: 149.0
Inv. Status	: In Stock
Rel. CAS No	: 1983945-11-4 (HCl salt)

SZ CAT No:	: SZ-P013019
CAS No	: 6973-09-7
Mol.F.	: C7H10N2O2S
Mol.Wt.	: 186.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-P013020
CAS No	: 1226499-98-4
Mol.F.	: C22H22N8
Mol.Wt.	: 398.5
Inv. Status	: Out of Stock
Rel. CAS No	: 2518037-55-1 (HCl salt)

SZ CAT No:	: SZ-P013021
CAS No	: NA
Mol.F.	: C20H21N7O2S : HCl
Mol.Wt.	: 423.5 . 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1252927-47-1 (free base)

SZ CAT No:	: SZ-P013022
CAS No	: 635702-64-6
Mol.F.	: C21H23N7O2S : HCl
Mol.Wt.	: 437.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 444731-52-6 (free base)

SZ CAT No:	: SZ-P013023
CAS No	: 1821666-73-2
Mol.F.	: C21H23N7O3S
Mol.Wt.	: 453.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013024
CAS No	: 1821666-74-3
Mol.F.	: C21H23N7O3S
Mol.Wt.	: 453.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013026
CAS No	: 1821666-71-0
Mol.F.	: C14H16N6
Mol.Wt.	: 268.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-P013028
CAS No	: 1821666-70-9
Mol.F.	: C12H15N5O2S
Mol.Wt.	: 293.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013029
CAS No	: 1821666-72-1
Mol.F.	: C21H21N7O2S
Mol.Wt.	: 435.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013030
CAS No	: 1821666-75-4
Mol.F.	: C21H21N7O3S
Mol.Wt.	: 451.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013033
CAS No	: 2795176-90-6
Mol.F.	: C21H22N6O3S
Mol.Wt.	: 438.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013034
CAS No	: NA
Mol.F.	: C21H22N8O3S
Mol.Wt.	: 466.5
Inv. Status	: Inquire

SZ CAT No:	: SZ-P013035
CAS No	: 6494-19-5
Mol.F.	: C8H7N3O2
Mol.Wt.	: 177.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2757538-00-2 (HCl salt)

SZ CAT No:	: SZ-P013036
CAS No	: 99-99-0
Mol.F.	: C7H7NO2
Mol.Wt.	: 137.1
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013031
CAS No	: NA
Mol.F.	: C21H23N7O2S : HCl
Mol.Wt.	: 437.5 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013D01
CAS No	: 1219591-97-5
Mol.F.	: C21H20D3N7O2S
Mol.Wt.	: 440.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-P013D02
CAS No	: 1219592-01-4
Mol.F.	: C21H17D6N7O2S
Mol.Wt.	: 443.6
Inv. Status	: Custom Synthesis