Pazopanib Desmethyl Impurity

N° de SZ CAT:	SZ-P013021
Número CAS	NA
Mol.F.	C20H21N7O2S : HCl
Peso Molecular	423.5 . 36.5
Status de Fatura	In Stock
Rel. CAS No	1252927-47-1 (free base)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: 5-(4-(2,3-Dimethyl-2H-indazol-6-ylamino)pyrimidin-2-ylamino)-2-methylbenzene sulfonamide hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: O=S(C1=CC(NC2=NC=CC(NC3=CC4=NN(C)C(C)=C4C=C3)=N2)=CC=C1C)(N)=O.Cl

Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S Kord
J Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.

Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu
Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102

Characterization of forced degradation products of pazopanib hydrochloride by UHPLC‐Q‐TOF/MS and in silico toxicity prediction
Prinesh N. Patel Pradipbhai D. Kalariya Mahesh Sharma Prabha Garg M. V. N Kumar Talluri S. Gananadhamu R. Srinivas
Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928

Development and validation of a stability indicating RP-HPLC method for the determination of Pazopanib in bulk drug and its pharmaceutical dosage form
Kishore Kumar Reddy Y, J. Raveendra Reddy and N. Devanna
J. Chem. Pharm. Res., 2015, 7(9):127-132

Validated RP-HPLC Method Development of Pazopanib in Bulk and its Pharmaceutical Dosage Form
Kiran Kumar Buralla, and Varadarajan Parthasarathy
Pharmaceutical Methods,2020,11,1,21-24.

Pazopanib Desmethyl Impurity is chemically 5-(4-(2,3-Dimethyl-2H-indazol-6-ylamino)pyrimidin-2-ylamino)-2-methylbenzene sulfonamide hydrochloride . Pazopanib Desmethyl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Pazopanib Desmethyl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pazopanib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Pazopanib Desmethyl Impurity

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N° de SZ CAT:	: SZ-P013001
Número CAS	: 444731-52-6
Mol.F.	: C21H23N7O2S
Peso Molecular	: 437.5
Status de Fatura	: In Stock
Rel. CAS No	: 635702-64-6 (HCl salt) ; 1310529-66-8 (2HCl salt) ; 635702-65-7 (mesylate salt)

N° de SZ CAT:	: SZ-P013002
Número CAS	: 80927-55-5
Mol.F.	: C4H3ClN2O
Peso Molecular	: 130.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 39875-64-4 (Na salt)

N° de SZ CAT:	: SZ-P013003
Número CAS	: 1226500-02-2
Mol.F.	: C26H23ClN10
Peso Molecular	: 511.0
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013004
Número CAS	: 1252927-44-8
Mol.F.	: C27H25ClN10
Peso Molecular	: 525.1
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013005
Número CAS	: 6274-28-8
Mol.F.	: C7H10N2O2S
Peso Molecular	: 186.2
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 854635-95-3 (HCl salt)

N° de SZ CAT:	: SZ-P013006
Número CAS	: 6269-91-6
Mol.F.	: C7H8N2O4S
Peso Molecular	: 216.2
Status de Fatura	: In Stock
Rel. CAS No	: 126148-19-4 (Na salt)

N° de SZ CAT:	: SZ-P013007
Número CAS	: 55873-09-1
Mol.F.	: C4H3ClN2O
Peso Molecular	: 130.5
Status de Fatura	: Custom Synthesis
Rel. CAS No	: 2818976-95-1 (HCl salt) ; 2913241-43-5 (Na salt)

N° de SZ CAT:	: SZ-P013008
Número CAS	: 444731-73-1
Mol.F.	: C9H9N3O2
Peso Molecular	: 191.2
Status de Fatura	: In Stock
Rel. CAS No	: 1810075-92-3 (HCl salt)

N° de SZ CAT:	: SZ-P013009
Número CAS	: 1313372-75-6
Mol.F.	: C8H7N3O2
Peso Molecular	: 177.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013010
Número CAS	: 1354224-47-7
Mol.F.	: C9H9N3O2
Peso Molecular	: 191.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013011
Número CAS	: 221681-92-1
Mol.F.	: C10H13N2
Peso Molecular	: 161.2
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013012
Número CAS	: 1414375-50-0
Mol.F.	: C21H23N7O3S
Peso Molecular	: 453.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013013
Número CAS	: 444731-74-2
Mol.F.	: C13H12ClN5
Peso Molecular	: 273.7
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P013014
Número CAS	: 635702-60-2
Mol.F.	: C9H11N3 : HCl
Peso Molecular	: 161.2 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 444731-72-0 (free base)

N° de SZ CAT:	: SZ-P013015
Número CAS	: 444731-75-3
Mol.F.	: C14H14ClN5
Peso Molecular	: 287.8
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P013016
Número CAS	: 1296888-47-5
Mol.F.	: C15H17N5O
Peso Molecular	: 283.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P013017
Número CAS	: 2518115-74-5
Mol.F.	: C21H23N7O2S : HCl
Peso Molecular	: 437.5 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 2369664-19-5 (free base)

N° de SZ CAT:	: SZ-P013018
Número CAS	: 3934-20-1
Mol.F.	: C4H2Cl2N2
Peso Molecular	: 149.0
Status de Fatura	: In Stock
Rel. CAS No	: 1983945-11-4 (HCl salt)

N° de SZ CAT:	: SZ-P013019
Número CAS	: 6973-09-7
Mol.F.	: C7H10N2O2S
Peso Molecular	: 186.2
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P013020
Número CAS	: 1226499-98-4
Mol.F.	: C22H22N8
Peso Molecular	: 398.5
Status de Fatura	: Out of Stock
Rel. CAS No	: 2518037-55-1 (HCl salt)

N° de SZ CAT:	: SZ-P013021
Número CAS	: NA
Mol.F.	: C20H21N7O2S : HCl
Peso Molecular	: 423.5 . 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 1252927-47-1 (free base)

N° de SZ CAT:	: SZ-P013022
Número CAS	: 635702-64-6
Mol.F.	: C21H23N7O2S : HCl
Peso Molecular	: 437.5 : 36.5
Status de Fatura	: In Stock
Rel. CAS No	: 444731-52-6 (free base)

N° de SZ CAT:	: SZ-P013023
Número CAS	: 1821666-73-2
Mol.F.	: C21H23N7O3S
Peso Molecular	: 453.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013024
Número CAS	: 1821666-74-3
Mol.F.	: C21H23N7O3S
Peso Molecular	: 453.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013026
Número CAS	: 1821666-71-0
Mol.F.	: C14H16N6
Peso Molecular	: 268.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-P013028
Número CAS	: 1821666-70-9
Mol.F.	: C12H15N5O2S
Peso Molecular	: 293.3
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013029
Número CAS	: 1821666-72-1
Mol.F.	: C21H21N7O2S
Peso Molecular	: 435.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013030
Número CAS	: 1821666-75-4
Mol.F.	: C21H21N7O3S
Peso Molecular	: 451.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013033
Número CAS	: 2795176-90-6
Mol.F.	: C21H22N6O3S
Peso Molecular	: 438.5
Status de Fatura	: Custom Synthesis

N° de SZ CAT:	: SZ-P013034
Número CAS	: NA
Mol.F.	: C21H22N8O3S
Peso Molecular	: 466.5
Status de Fatura	: Inquire