Palbociclib Pyridine N-Oxide

SZ CAT No:	SZ-P015006
CAS No	2098673-40-4
Mol.F.	C24H29N7O3
Mol.Wt.	463.5
Inv. Status	In Stock
Rel. CAS No	2098673-44-8 (HCl salt)

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Chemical Name: 2-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1C(C(C)=O)=C(C)C(C=NC(NC2=CC=C(N3CCNCC3)C=[N+]2[O-])=N4)=C4N1C5CCCC5

New stability-indicating liquid chromatographic method for determination of palbociclib (an anti-breast cancer drug)
By Kallepalli, Pramadvara; Annapurna, Mukthinuthalapati Mathrusri
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S270-S275

Optimization and validation of RP-HPLC method for simultaneous estimation of palbociclib and letrozole
By Dange, Yuvraj; Bhinge, Somnath; Salunkhe, Vijay
From Toxicology Mechanisms and Methods (2018), 28(3), 187-194

Palbociclib Pyridine N-Oxide is chemically 2-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide. Palbociclib Pyridine N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Palbociclib Pyridine N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Palbociclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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