Hydrocortisone 21-phosphate

SZ CAT No:	SZ-H008091
CAS No	3863-59-0
Mol.F.	C21H31O8P
Mol.Wt.	442.4
Inv. Status	Custom Synthesis
Rel. CAS No	6000-74-4 (2Na salt) ; 38048-30-5 (Na salt)

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Chemical Name: 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl dihydrogen phosphate

Synonym: Cortisol 21-phosphate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=P(O)(OCC([C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C)=O)=O)O

Comparative study of two different chromatographic approaches for quantitation of hydrocortisone acetate and pramoxine hydrochloride in presence of their impurities
Fawzia Ibrahim a , Asmaa Kamal El-Deen a,b , Kuniyoshi Shimizu
Journal of Food and Drug Analysis Volume 26, Issue 3, July 2018, Pages 1160-1170

Novel stability indicating UHPLC method development and validation for simultaneous quantification of hydrocortisone acetate, pramoxine hydrochloride, potassium sorbate and sorbic acid in topical cream formulation
Lakshmi Narasimha RaoKatakamaThirupathiDongalabSanthosh KumarEttaboina
Talanta Open Volume 1, August 2020, 100004

Novel eco-friendly chromatographic determinations of hydrocortisone acetate, fusidic acid, their pharmacologically active impurities and pharmaceutical excipients: a comparative study
Maha M. Abdelrahman, Raghda Abdelmoneim Emam, Nouruddin W. Ali & Eglal A. Abdelaleem
Chemical Papers volume 74, pages2175–2187(2020)

An RP-HPLC Method for the Stability-Indicating Analysis of Impurities of Both Fusidic Acid and Betamethasone-17-Valerate in a Semi-Solid Pharmaceutical Dosage Form
Jonathan Byrne, Trinidad Velasco-Torrijos, Robert Reinhardt
Journal of Chromatographic Science, Volume 53, Issue 9, October 2015, Pages 1498–1503

Analytical method development and determination of hydrocortisone acetate and fusidic acid simultaneously in cream formulation, by reversed‐phase HPLC
Nawaz Rasool, Qudsia Kanwal, Muhammad Waseem
Biomedical Chromatography Volume35, Issue3 March 2021 e4997

Hydrocortisone 21-phosphate is chemically 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl dihydrogen phosphate. It is also known as Cortisol 21-phosphate. Hydrocortisone 21-phosphate is supplied with detailed characterization data compliant with regulatory guideline. Hydrocortisone 21-phosphate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hydrocortisone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Hydrocortisone EP Impurity N

SZ CAT No:	: SZ-H008015
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Mol.F.	: C42H58O10
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SZ CAT No:	: SZ-H008022
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SZ CAT No:	: SZ-H008029
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Mol.F.	: C26H38O6
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Prednisolone-21-Valerate

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SZ CAT No:	: SZ-H008043
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SZ CAT No:	: SZ-H008044
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SZ CAT No:	: SZ-H008045
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SZ CAT No:	: SZ-H008046
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Hydrocortisone Impurity 2

SZ CAT No:	: SZ-H008047
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Mol.F.	: C29H44O7
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Hydrocortisone Impurity 3

SZ CAT No:	: SZ-H008048
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SZ CAT No:	: SZ-H008049
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Hydrocortisone Un-Symmetrical Dimer

SZ CAT No:	: SZ-H008052
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Cortisone 21-Hemisuccinate

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SZ CAT No:	: SZ-H008055
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SZ CAT No:	: SZ-H008060
CAS No	: 97154-36-4
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Mol.Wt.	: 416.5
Inv. Status	: Custom Synthesis

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SZ CAT No:	: SZ-H008062
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Inv. Status	: Custom Synthesis

21-Deoxy Cortisone

SZ CAT No:	: SZ-H008063
CAS No	: 1882-82-2
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Mol.Wt.	: 344.5
Inv. Status	: Custom Synthesis

9 Alpha Hydroxyl Hydrocortisone Acetate

SZ CAT No:	: SZ-H008064
CAS No	: 50733-56-7
Mol.F.	: C23H32O7
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SZ CAT No:	: SZ-H008065
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SZ CAT No:	: SZ-H008066
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Delta 8,9 Cortisone Acetate

SZ CAT No:	: SZ-H008067
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Mol.F.	: C23H28O6
Mol.Wt.	: 400.5
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Hydrocortisone 17-Butyrate 3-Enol Methyl Ether

SZ CAT No:	: SZ-H008068
CAS No	: NA
Mol.F.	: C26H38O6
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SZ CAT No:	: SZ-H008069
CAS No	: NA
Mol.F.	: C21H30O5
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SZ CAT No:	: SZ-H008070
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Mol.F.	: C21H30O5
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SZ CAT No:	: SZ-H008071
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Mol.Wt.	: 444.5
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SZ CAT No:	: SZ-H008076
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Mol.Wt.	: 400.5
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SZ CAT No:	: SZ-H008077
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Mol.Wt.	: 376.4
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Mol.F.	: C21H26O5
Mol.Wt.	: 358.4
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SZ CAT No:	: SZ-H008079
CAS No	: 3597-44-2
Mol.F.	: C20H26O5
Mol.Wt.	: 346.4
Inv. Status	: Custom Synthesis

Hydrocortisone Impurity 16

SZ CAT No:	: SZ-H008080
CAS No	: 2601-23-2
Mol.F.	: C23H26O6
Mol.Wt.	: 398.5
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Hydrocortisone Impurity 17

SZ CAT No:	: SZ-H008081
CAS No	: 27149-67-3
Mol.F.	: C21H30O5
Mol.Wt.	: 362.5
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SZ CAT No:	: SZ-H008082
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Mol.F.	: C21H30O5
Mol.Wt.	: 362.5
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SZ CAT No:	: SZ-H008083
CAS No	: 10184-70-0
Mol.F.	: C21H28O4
Mol.Wt.	: 344.5
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SZ CAT No:	: SZ-H008084
CAS No	: 3331-69-9
Mol.F.	: C25H34O7
Mol.Wt.	: 446.5
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Hydrocortisone Impurity 20

SZ CAT No:	: SZ-H008085
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Mol.F.	: C21H29ClO4
Mol.Wt.	: 380.9
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SZ CAT No:	: SZ-H008086
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Mol.F.	: C23H30O6
Mol.Wt.	: 402.5
Inv. Status	: In Stock

6-β-Hydroxycortisol-d4

SZ CAT No:	: SZ-H008D02
CAS No	: 1261254-51-6
Mol.F.	: C21H26D4O6
Mol.Wt.	: 382.5
Inv. Status	: Custom Synthesis

Hydrocortisone 17-phosphate

SZ CAT No:	: SZ-H008087
CAS No	: 220489-76-9
Mol.F.	: C21H31O8P
Mol.Wt.	: 442.4
Inv. Status	: Custom Synthesis

6-Beta Hydroxy Hydrocortisone Phosphate

SZ CAT No:	: SZ-H008088
CAS No	: NA
Mol.F.	: C21H31O9P
Mol.Wt.	: 458.4
Inv. Status	: Custom Synthesis

Hydrocortisone Impurity 23

SZ CAT No:	: SZ-H008089
CAS No	: NA
Mol.F.	: C20H28O5
Mol.Wt.	: 348.4
Inv. Status	: Custom Synthesis

Hydrocortisone Impurity 24

SZ CAT No:	: SZ-H008090
CAS No	: NA
Mol.F.	: C21H29O7P
Mol.Wt.	: 424.4
Inv. Status	: In Stock