Ziprasidone EP Impurity D

SZ CAT No:	SZ-Z002005
CAS No	1303996-68-0
Mol.F.	C42H40Cl2N8O3S2
Mol.Wt.	839.9
Inv. Status	Custom Synthesis

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Chemical Name: 5,5'-Bis[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-6,6'-dichloro-3-hydroxy-1,1',3,3'-tetrahydro-2H,2'H-3,3'-biindole-2,2'-dione (as per EP) ; 5,5′-Bis{2-[4-(benzoisothiazol-3-yl)piperazin-1-yl]ethyl}-6,6′-dichloro-3-hydroxy-3,3′-biindoline-2,2′-dione (as per USP)

Synonym: Ziprasidone USP Related Compound C

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1NC2=C(C=C(CCN3CCN(C4=NSC5=C4C=CC=C5)CC3)C(Cl)=C2)C1(O)C6C(NC7=C6C=C(CCN8CCN(C9=NSC%10=C9C=CC=C%10)CC8)C(Cl)=C7)=O

Development and Validation of an HPLC Method for Determination of Ziprasidone and Its Impurities in Pharmaceutical Dosage Forms
Marija Pavlovic, Marija Malesevic, Katarina Nikolic, Danica Agbaba
Journal of AOAC INTERNATIONAL, Volume 94, Issue 3, 1 May 2011, Pages 713–722

Optimization of the Thin-Layer Chromatography Method for the Separation of Ziprasidone and Its Impurities
Darija Obradović, Slavica Filipic, Katarina Nikolic & Danica Agbaba
JPC – Journal of Planar Chromatography – Modern TLC volume 29, pages239–246(2016)

Optimization of TLC method for separation and determination of ziprasidone and its impurities
Darija Obradović,Slavica Filipić,Katarina Nikolić,Marija Čarapić &Danica Agbaba
Journal of Liquid Chromatography & Related Technologies Volume 39, 2016 - Issue 5-6: Special Issue: Thin Layer Chromatography Pages 271-276

Ziprasidone EP Impurity D is chemically 5,5'-Bis[2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-yl]ethyl]-6,6'-dichloro-3-hydroxy-1,1',3,3'-tetrahydro-2H,2'H-3,3'-biindole-2,2'-dione (as per EP) ; 5,5′-Bis{2-[4-(benzoisothiazol-3-yl)piperazin-1-yl]ethyl}-6,6′-dichloro-3-hydroxy-3,3′-biindoline-2,2′-dione (as per USP). It is also known as Ziprasidone USP Related Compound C. Ziprasidone EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Ziprasidone EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ziprasidone-.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-Z002001
CAS No	: 138982-67-9
Mol.F.	: C21H21ClN4OS : HCl : H2O
Mol.Wt.	: 412.9 : 36.5 : 18.0
Inv. Status	: In Stock
Rel. CAS No	: 146939-27-7 (free base)
Rel. CAT No	: SZ-Z002039 ,

SZ CAT No:	: SZ-Z002004
CAS No	: 1798033-44-9
Mol.F.	: C21H22ClN4O2S : Na
Mol.Wt.	: 429.9 : 23.0
Inv. Status	: In Stock
Rel. CAS No	: 1159977-64-6 (free base)

SZ CAT No:	: SZ-Z002032
CAS No	: 122883-93-6
Mol.F.	: C21H21ClN4OS : HCl
Mol.Wt.	: 412.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 146939-27-7 (free base)

SZ CAT No:	: SZ-Z002034
CAS No	: 128396-56-5
Mol.F.	: C11H13N3OS
Mol.Wt.	: 235.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 136546-45-7 (HCl salt)

SZ CAT No:	: SZ-Z002035
CAS No	: 188797-77-5
Mol.F.	: C21H21ClN4O3S
Mol.Wt.	: 444.9
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1246820-87-0 (HCl salt)

Ziprasidone EP Impurity D

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SZ CAT No:	: SZ-Z002002
CAS No	: 87691-87-0
Mol.F.	: C11H13N3S
Mol.Wt.	: 219.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002003
CAS No	: 1159977-56-6
Mol.F.	: C21H19ClN4O2S
Mol.Wt.	: 426.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002005
CAS No	: 1303996-68-0
Mol.F.	: C42H40Cl2N8O3S2
Mol.Wt.	: 839.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002006
CAS No	: 1159977-04-4
Mol.F.	: C28H24ClN5OS2
Mol.Wt.	: 546.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002007
CAS No	: 223586-82-1
Mol.F.	: C18H16N4S2
Mol.Wt.	: 352.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002008
CAS No	: 118289-55-7
Mol.F.	: C10H9Cl2NO
Mol.Wt.	: 230.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002009
CAS No	: 884305-06-0
Mol.F.	: C10H9Cl2NO2
Mol.Wt.	: 246.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002010
CAS No	: 188797-80-0
Mol.F.	: C21H21ClN4O2S
Mol.Wt.	: 428.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002011
CAS No	: 118305-72-9
Mol.F.	: C21H22N4OS
Mol.Wt.	: 378.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002012
CAS No	: 188797-76-4
Mol.F.	: C21H21ClN4O2S
Mol.Wt.	: 428.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002013
CAS No	: 884305-08-2
Mol.F.	: C21H21ClN4O2S
Mol.Wt.	: 428.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002014
CAS No	: 684269-12-3
Mol.F.	: C24H25ClN4OS
Mol.Wt.	: 453.0
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002015
CAS No	: 160384-40-7
Mol.F.	: C21H21ClN4O4S
Mol.Wt.	: 460.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002016
CAS No	: 1797879-13-0
Mol.F.	: C19H19ClN4O3S
Mol.Wt.	: 418.9
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002017
CAS No	: 131779-46-9
Mol.F.	: C16H21N3O2S
Mol.Wt.	: 319.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002018
CAS No	: 160384-37-2
Mol.F.	: C19H16Cl2N4O2S
Mol.Wt.	: 435.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002019
CAS No	: 160384-38-3
Mol.F.	: C19H18Cl2N4O2S
Mol.Wt.	: 437.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002020
CAS No	: 774595-88-9
Mol.F.	: C22H23ClN4OS
Mol.Wt.	: 427.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002021
CAS No	: 2514708-83-7
Mol.F.	: C11H14ClN3O2S
Mol.Wt.	: 287.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002022
CAS No	: 56341-37-8
Mol.F.	: C8H6ClNO
Mol.Wt.	: 167.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002D01
CAS No	: 1126745-58-1
Mol.F.	: C21H13D8ClN4OS
Mol.Wt.	: 421.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002024
CAS No	: 884305-07-1
Mol.F.	: C21H19ClN4O2S
Mol.Wt.	: 426.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002025
CAS No	: NA
Mol.F.	: C16H14N4S2
Mol.Wt.	: 326.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002026
CAS No	: 2327157-90-2
Mol.F.	: C13H15N3OS
Mol.Wt.	: 261.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002027
CAS No	: 118307-04-3
Mol.F.	: C10H7Cl2NO2
Mol.Wt.	: 244.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002028
CAS No	: 147124-32-1
Mol.F.	: C11H10ClNO6
Mol.Wt.	: 287.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002029
CAS No	: 118306-76-6
Mol.F.	: C10H10ClNO
Mol.Wt.	: 195.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-Z002030
CAS No	: NA
Mol.F.	: C26H18Cl3N3O3
Mol.Wt.	: 526.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002031
CAS No	: NA
Mol.F.	: C17H12Cl2N2O2
Mol.Wt.	: 347.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-Z002033
CAS No	: 194280-91-6
Mol.F.	: C22H25ClN4OS
Mol.Wt.	: 429.0
Inv. Status	: Custom Synthesis