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Vildagliptin Chloroacetyl Amide (S)-Isomer

SZ CAT No SZ-V008023
CAS No 214398-99-9
Mol.F. C7H11ClN2O2
Mol.Wt. 190.6
Inv. Status In Stock


Chemical Name: (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide

Smiles: O=C(N(CCC1)[C@@H]1C(N)=O)CCl

Inchi: InChI=1S/C12H19NO3/c14-10(15)6-13-11-2-8-1-9(3-11)5-12(16,4-8)7-11/h8-9,13,16H,1-7H2,(H,14,15)/t8-,9?,11+,12-/m1/s1

Identification, isolation and characterization of potential process-related impurity and its degradation product in vildagliptin
Neeraj Kumar, Subba Rao Devineni, Gurmeet Singh, A.Kadirappa, Shailendra Kumar, Dubey, Pramod Kumar
Journal of Pharmaceutical and Biomedical Analysis Volume 119, 5 February 2016, Pages 114-121
 
Development and validation of a cyclodextrin‐modified capillary electrophoresis method for the enantiomeric separation of vildagliptin enantiomers
Adrienn Kazsoki  Ida Fejős  Tamás Sohajda  Wei Zhou  Wenhui Hu  Lajos Szente  Szabolcs Béni
Electrophoresis Volume37, Issue10 May 2016 Pages 1318-1325
 
New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms
Sharif Arar,Enas Al-Qudah,Muhammad Alzweiri &Kamal Sweidan
Journal of Liquid Chromatography & Related Technologies  Volume 43, 2020 - Issue 15-16 Pages 633-644