Venetoclax Nitroso Impurity 1

SZ CAT No:	SZ-V022043
CAS No	NA
Mol.F.	C45H49ClN8O8S
Mol.Wt.	897.4
Inv. Status	Inquire
Shipping Condition	Ambient Temperature

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Chemical Name: 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(NS(=O)(C1=CC=C(N(N=O)CC2CCOCC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7

Venetoclax Nitroso Impurity 1 is chemically 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Venetoclax Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Venetoclax Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venetoclax.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Venetoclax Impurity I

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Metabolite M27

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Venetoclax Impurity 2

SZ CAT No:	: SZ-V022004
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Mol.F.	: C45H52ClN7O5S
Mol.Wt.	: 838.5
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Venetoclax Impurity 3

SZ CAT No:	: SZ-V022005
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Mol.F.	: C15H11FN2O3
Mol.Wt.	: 286.3
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Venetoclax Impurity 4

SZ CAT No:	: SZ-V022006
CAS No	: NA
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.5
Inv. Status	: In Stock

Venetoclax Impurity 5

SZ CAT No:	: SZ-V022007
CAS No	: NA
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.5
Inv. Status	: Custom Synthesis

Venetoclax-d8

SZ CAT No:	: SZ-V022D01
CAS No	: 1257051-06-1
Mol.F.	: C45H42D8ClN7O7S
Mol.Wt.	: 876.5
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Deschloro Venetoclax Impurity

SZ CAT No:	: SZ-V022008
CAS No	: 2573767-91-4
Mol.F.	: C45H51N7O7S
Mol.Wt.	: 834.0
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Venetoclax-N-Oxide Impurity

SZ CAT No:	: SZ-V022009
CAS No	: 2469279-00-1
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.5
Inv. Status	: In Stock

Venetoclax Impurity 6

SZ CAT No:	: SZ-V022010
CAS No	: 1228779-96-1
Mol.F.	: C12H17N3O5S
Mol.Wt.	: 315.3
Inv. Status	: In Stock

Venetoclax Impurity 7

SZ CAT No:	: SZ-V022011
CAS No	: 1228837-05-5
Mol.F.	: C15H17ClO
Mol.Wt.	: 248.8
Inv. Status	: In Stock

Venetoclax Oxalic Acid

SZ CAT No:	: SZ-V022012
CAS No	: NA
Mol.F.	: C26H32N6O12S2 : 2(C6H15N)
Mol.Wt.	: 684.7 : 2(101.2)
Inv. Status	: Custom Synthesis

Venetoclax Impurity 8

SZ CAT No:	: SZ-V022013
CAS No	: NA
Mol.F.	: C46H48ClN8O6S
Mol.Wt.	: 876.4
Inv. Status	: Custom Synthesis

Venetoclax Impurity 9 (HCl salt)

SZ CAT No:	: SZ-V022014
CAS No	: 2254393-29-6
Mol.F.	: C33H35ClN4O3 : HCl
Mol.Wt.	: 571.1 : 36.5
Inv. Status	: In Stock

Venetoclax Impurity 10

SZ CAT No:	: SZ-V022015
CAS No	: 2573767-90-3
Mol.F.	: C26H24FN5O7S
Mol.Wt.	: 569.6
Inv. Status	: In Stock

Venetoclax Impurity 11

SZ CAT No:	: SZ-V022016
CAS No	: 2573767-92-5
Mol.F.	: C47H52ClN7O8S
Mol.Wt.	: 910.5
Inv. Status	: Custom Synthesis

Venetoclax Impurity 12

SZ CAT No:	: SZ-V022017
CAS No	: NA
Mol.F.	: C78H83Cl2N11O9S
Mol.Wt.	: 1421.6
Inv. Status	: Custom Synthesis

Venetoclax Impurity 13

SZ CAT No:	: SZ-V022018
CAS No	: 2573767-94-7
Mol.F.	: C71H73ClN12O14S2
Mol.Wt.	: 1418.0
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Venetoclax Impurity 15

SZ CAT No:	: SZ-V022030
CAS No	: NA
Mol.F.	: C19H27ClN2O
Mol.Wt.	: 334.9
Inv. Status	: Custom Synthesis

Venetoclax Impurity 16

SZ CAT No:	: SZ-V022031
CAS No	: 2142574-09-0
Mol.F.	: C14H9FN2O3
Mol.Wt.	: 272.2
Inv. Status	: Custom Synthesis

Venetoclax Impurity 17

SZ CAT No:	: SZ-V022032
CAS No	: NA
Mol.F.	: C15H11FN2O3
Mol.Wt.	: 286.3
Inv. Status	: In Stock

Venetoclax Impurity 18

SZ CAT No:	: SZ-V022033
CAS No	: NA
Mol.F.	: C13H18N2O6S
Mol.Wt.	: 330.4
Inv. Status	: Custom Synthesis

Venetoclax Impurity 19

SZ CAT No:	: SZ-V022034
CAS No	: NA
Mol.F.	: C12H16N2O6S
Mol.Wt.	: 316.3
Inv. Status	: Custom Synthesis

Venetoclax Impurity 23

SZ CAT No:	: SZ-V022037
CAS No	: 2270190-88-8
Mol.F.	: C78H83Cl2N11O9S
Mol.Wt.	: 1421.6
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Venetoclax Impurity 24

SZ CAT No:	: SZ-V022038
CAS No	: NA
Mol.F.	: C48H45ClN6O5
Mol.Wt.	: 821.4
Inv. Status	: Custom Synthesis

Venetoclax Impurity 14

SZ CAT No:	: SZ-V022019
CAS No	: NA
Mol.F.	: C23H16F2N2O5
Mol.Wt.	: 438.4
Inv. Status	: Custom Synthesis

Venetoclax Desfluoro Acid Impurity

SZ CAT No:	: SZ-V022020
CAS No	: NA
Mol.F.	: C15H12N2O3
Mol.Wt.	: 268.3
Inv. Status	: Custom Synthesis

Venetoclax Chloro Coupled Acid Impurity

SZ CAT No:	: SZ-V022021
CAS No	: NA
Mol.F.	: C52H61ClN6O3
Mol.Wt.	: 853.5
Inv. Status	: Custom Synthesis

Venetoclax N-Hydroxy Acid Impurity

SZ CAT No:	: SZ-V022022
CAS No	: NA
Mol.F.	: C33H35ClN4O4
Mol.Wt.	: 587.1
Inv. Status	: Custom Synthesis

Venetoclax N-Coupled Acid Impurity

SZ CAT No:	: SZ-V022023
CAS No	: NA
Mol.F.	: C47H43ClN6O6
Mol.Wt.	: 823.3
Inv. Status	: Custom Synthesis

Venetoclax Desfluoro Impurity

SZ CAT No:	: SZ-V022024
CAS No	: NA
Mol.F.	: C26H25N5O7S
Mol.Wt.	: 551.6
Inv. Status	: Custom Synthesis

Venetoclax Chloro Coupled Impurity

SZ CAT No:	: SZ-V022025
CAS No	: NA
Mol.F.	: C64H76ClN9O7S
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Venetoclax Acyl Urea Impurity 1

SZ CAT No:	: SZ-V022028
CAS No	: NA
Mol.F.	: C41H52ClN7O3
Mol.Wt.	: 726.4
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Venetoclax Acyl Urea Impurity 2

SZ CAT No:	: SZ-V022029
CAS No	: NA
Mol.F.	: C41H52ClN7O3
Mol.Wt.	: 726.4
Inv. Status	: Custom Synthesis

Venetoclax Impurity 25

SZ CAT No:	: SZ-V022039
CAS No	: NA
Mol.F.	: C16H26N2OSi
Mol.Wt.	: 290.5
Inv. Status	: Custom Synthesis

Venetoclax Impurity 26

SZ CAT No:	: SZ-V022040
CAS No	: NA
Mol.F.	: C16H26N2OSi
Mol.Wt.	: 290.5
Inv. Status	: Custom Synthesis

Venetoclax Impurity 27

SZ CAT No:	: SZ-V022041
CAS No	: 1228943-80-3
Mol.F.	: C9H13ClO
Mol.Wt.	: 172.7
Inv. Status	: In Stock

Venetoclax N-Hydroxylamine Impurity

SZ CAT No:	: SZ-V022042
CAS No	: NA
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.4
Inv. Status	: Custom Synthesis

Venetoclax Nitroso Impurity 1

SZ CAT No:	: SZ-V022043
CAS No	: NA
Mol.F.	: C45H49ClN8O8S
Mol.Wt.	: 897.4
Inv. Status	: Inquire

Venetoclax Nitroso Impurity 2

SZ CAT No:	: SZ-V022044
CAS No	: NA
Mol.F.	: C45H48ClN9O9S
Mol.Wt.	: 926.4
Inv. Status	: Inquire

Venetoclax Nitroso Impurity 3

SZ CAT No:	: SZ-V022045
CAS No	: NA
Mol.F.	: C45H49ClN8O8S
Mol.Wt.	: 897.4
Inv. Status	: Inquire

Venetoclax Impurity 29

SZ CAT No:	: SZ-V022046
CAS No	: 2412506-53-5
Mol.F.	: C90H100N14O14S2
Mol.Wt.	: 1666.0
Inv. Status	: Limited Stock

Venetoclax Impurity 30

SZ CAT No:	: SZ-V022047
CAS No	: NA
Mol.F.	: C30H33N7O9S
Mol.Wt.	: 667.7
Inv. Status	: Custom Synthesis

Venetoclax Impurity 31

SZ CAT No:	: SZ-V022048
CAS No	: NA
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.4
Inv. Status	: Custom Synthesis

Venetoclax Impurity 32

SZ CAT No:	: SZ-V022049
CAS No	: 2573767-96-9
Mol.F.	: C45H50ClN7O8S
Mol.Wt.	: 884.4
Inv. Status	: Custom Synthesis

Venetoclax Nitroso Impurity 4

SZ CAT No:	: SZ-V022050
CAS No	: NA
Mol.F.	: C19H26ClN3O
Mol.Wt.	: 347.9
Inv. Status	: In Stock

Venetoclax Nitroso Impurity 5

SZ CAT No:	: SZ-V022051
CAS No	: NA
Mol.F.	: C12H16N4O6S
Mol.Wt.	: 344.3
Inv. Status	: Custom Synthesis

Venetoclax Impurity 33

SZ CAT No:	: SZ-V022052
CAS No	: NA
Mol.F.	: C39H40ClN7O6S
Mol.Wt.	: 770.3
Inv. Status	: Custom Synthesis

Venetoclax Impurity 34

SZ CAT No:	: SZ-V022053
CAS No	: NA
Mol.F.	: C84H96N14O14S2
Mol.Wt.	: 1589.9
Inv. Status	: Custom Synthesis

Venetoclax Impurity 35

SZ CAT No:	: SZ-V022054
CAS No	: NA
Mol.F.	: C39H38ClFN6O6S
Mol.Wt.	: 773.3
Inv. Status	: Custom Synthesis

Venetoclax Nitroso Impurity 1

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