Tigecycline 12-oxo-11-hydroxy impurity (USP)

SZ CAT No:	SZ-T048010
CAS No	1633815-62-9
Mol.F.	C29H37N5O8
Mol.Wt.	583.6
Inv. Status	In Stock

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Chemical Name: (4S,4aS,12aS)-9-[2-(tert-Butylamino)acetamido]-4,7-bis(dimethylamino)- 3,10,11,12a-tetrahydroxy-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-naphthacenecarboxamide (as per USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@@](C(O)=C(C(C1=C(C(NC(CNC(C)(C)C)=O)=C2)O)=O)C3=CC1=C2N(C)C)(C(C(C(N)=O)=C4O)=O)[C@](C3)([H])[C@@H]4N(C)C

Estimation of related substances in tigecycline by rp-hplc Method
By Mohan, Bavireddi; Sharma, R. S. K.; Rao, S. V. Murali Mohan; Gopal, N. V. S. Venu
From Oriental Journal of Chemistry (2017), 33(5), 2608-2615

Development and validation of an LC-MS/MS method for determination of tigecycline and its epimer in human plasma and its application in a pharmacokinetic study
By Wang, Longyuan; Hu, Xiaoxiao; Zhu, Hong; Zhang, Xiaotian; Wang, Chuan; Han, Zhiwu
From Acta Chromatographica (2016), 28(2), 239-253

Development and validation of a novel HPLC method for quantification of tigecycline in bulk and nanoparticle based suspension
By Geetha, M.; Prakash, Rao B.; Rajendra, C. E.; Chaluvaraju, K. C.; Manjula, B. P.
From Journal of Pharmacy and Chemistry (2015), 9(1), 22-26

Tigecycline 12-oxo-11-hydroxy impurity (USP) is chemically (4S,4aS,12aS)-9-[2-(tert-Butylamino)acetamido]-4,7-bis(dimethylamino)- 3,10,11,12a-tetrahydroxy-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-naphthacenecarboxamide (as per USP). Tigecycline 12-oxo-11-hydroxy impurity (USP) is supplied with detailed characterization data compliant with regulatory guideline. Tigecycline 12-oxo-11-hydroxy impurity (USP) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tigecycline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Tigecycline 12-oxo-11-hydroxy impurity (USP)

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Mol.F.	: C29H37N5O8
Mol.Wt.	: 583.6
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Mol.F.	: C23H27N3O7 : HCl
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Inv. Status	: In Stock