Tigecycline EP Impurity B

SZ CAT No:	SZ-T048005
CAS No	149934-19-0
Mol.F.	C23H28N4O7
Mol.Wt.	472.5
Inv. Status	Custom Synthesis
Rel. CAS No	149934-21-4 (HCl salt)

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Chemical Name: (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (as per EP)

Synonym: 9-Aminominocycline (EP) ; Tigecycline USP Related Compound B

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(N)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N

Estimation of related substances in tigecycline by rp-hplc Method
By Mohan, Bavireddi; Sharma, R. S. K.; Rao, S. V. Murali Mohan; Gopal, N. V. S. Venu
From Oriental Journal of Chemistry (2017), 33(5), 2608-2615

Development and validation of an LC-MS/MS method for determination of tigecycline and its epimer in human plasma and its application in a pharmacokinetic study
By Wang, Longyuan; Hu, Xiaoxiao; Zhu, Hong; Zhang, Xiaotian; Wang, Chuan; Han, Zhiwu
From Acta Chromatographica (2016), 28(2), 239-253

Development and validation of a novel HPLC method for quantification of tigecycline in bulk and nanoparticle based suspension
By Geetha, M.; Prakash, Rao B.; Rajendra, C. E.; Chaluvaraju, K. C.; Manjula, B. P.
From Journal of Pharmacy and Chemistry (2015), 9(1), 22-26

Tigecycline EP Impurity B is chemically (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (as per EP). It is also known as 9-Aminominocycline (EP) ; Tigecycline USP Related Compound B. Tigecycline EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Tigecycline EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tigecycline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Tigecycline EP Impurity B

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SZ CAT No:	: SZ-T048009
CAS No	: 153621-85-3
Mol.F.	: C25H30N4O8
Mol.Wt.	: 514.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048001
CAS No	: 220620-09-7
Mol.F.	: C29H39N5O8
Mol.Wt.	: 585.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048002
CAS No	: 1138343-10-8
Mol.F.	: C29H38N5O10
Mol.Wt.	: 616.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048003
CAS No	: 149934-21-4
Mol.F.	: C23H28N4O7 : HCl
Mol.Wt.	: 472.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048005
CAS No	: 149934-19-0
Mol.F.	: C23H28N4O7
Mol.Wt.	: 472.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048006
CAS No	: 1422262-97-2
Mol.F.	: C29H39N5O8
Mol.Wt.	: 585.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048007
CAS No	: 1268494-46-7
Mol.F.	: C26H32N4O8
Mol.Wt.	: 528.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048008
CAS No	: 1268494-40-1
Mol.F.	: C27H32N4O9
Mol.Wt.	: 556.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048010
CAS No	: 1633815-62-9
Mol.F.	: C29H37N5O8
Mol.Wt.	: 583.6
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048011
CAS No	: NA
Mol.F.	: C28H37N5O8
Mol.Wt.	: 571.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048012
CAS No	: NA
Mol.F.	: C27H34N4O8
Mol.Wt.	: 542.6
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-T048013
CAS No	: NA
Mol.F.	: C27H32N4O9
Mol.Wt.	: 556.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048014
CAS No	: NA
Mol.F.	: C30H41N5O9
Mol.Wt.	: 615.7
Inv. Status	: Limited Stock

SZ CAT No:	: SZ-T048016
CAS No	: NA
Mol.F.	: C29H40N6O7
Mol.Wt.	: 584.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048D01
CAS No	: NA
Mol.F.	: C29H30D9N5O8
Mol.Wt.	: 594.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048017
CAS No	: NA
Mol.F.	: C29H39N5O8 : C29H39N5O8 : C23H28N4O7 : C23H27N3O7
Mol.Wt.	: 585.7 : 585.7 : 472.5 : 457.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048026
CAS No	: NA
Mol.F.	: C33H46N6O9
Mol.Wt.	: 670.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048027
CAS No	: NA
Mol.F.	: C33H46N6O9
Mol.Wt.	: 670.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048030
CAS No	: NA
Mol.F.	: C30H41N5O8
Mol.Wt.	: 599.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048032
CAS No	: NA
Mol.F.	: C32H46N6O8
Mol.Wt.	: 642.8
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048033
CAS No	: NA
Mol.F.	: C28H37N5O8
Mol.Wt.	: 571.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048020
CAS No	: NA
Mol.F.	: C27H32N4O9 : XC2HF3O2
Mol.Wt.	: 556.6 : X(114.0)
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-T048021
CAS No	: NA
Mol.F.	: C29H38N6O9
Mol.Wt.	: 614.7
Inv. Status	: In Stock

SZ CAT No:	: SZ-T048022
CAS No	: 149934-16-7
Mol.F.	: C23H26N4O9
Mol.Wt.	: 502.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-T048023
CAS No	: 13614-98-7
Mol.F.	: C23H27N3O7 : HCl
Mol.Wt.	: 457.5 : 36.5
Inv. Status	: In Stock