Saxagliptin Impurity 56

SZ CAT No:	SZ-S005079
CAS No	1669461-40-8
Mol.F.	C37H39N3O2
Mol.Wt.	557.7
Inv. Status	Custom Synthesis

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (1S,3S,5S)-2-((2S)-2-(3-hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: N#C[C@H]1N(C([C@H](C23CC4(O)CC(C3)CC(C4)C2)NC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=O)[C@@]8([H])C[C@@]8([H])C1

Development and validation of RP-HPLC method for simultaneous estimation of saxagliptin and dapagliflozin
By Desai, Charmy P.; Chaudhary, Ankit B.; Patel, Bhoomi D.
From World Journal of Pharmacy and Pharmaceutical Sciences (2018), 7(5), 803-812

Gradient elution RP-HPLC method for the determination of related substances in saxagliptin
By Li, Xiaoyan; Liu, Fei
From Zhongguo Yaopin Biaozhun (2015), 16(1), 16-19

Development and validation of simple stability indicating RP-HPLC method for analysis of saxagliptin and its forced degradation impurities in bulk drug and pharmaceutical dosage form
By Chhabda, Pawanjeet J.; Balaji, M.; Srinivasarao, V.; Ramakrishna, K.; Apparao, K. M. Ch.
From International Journal of Research and Development in Pharmacy & Life Sciences (2014), 3(3), 993-1003, 11 pp..

Saxagliptin Impurity 56 is chemically (1S,3S,5S)-2-((2S)-2-(3-hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Saxagliptin Impurity 56 is supplied with detailed characterization data compliant with regulatory guideline. Saxagliptin Impurity 56 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Saxagliptin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Mol.F.	: C1513C3H25N3O2
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Saxagliptin-15N,D2 Hydrochloride

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SZ CAT No:	: SZ-S005D04
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N-Formyl Saxagliptin-13C3

SZ CAT No:	: SZ-S005D05
CAS No	: NA
Mol.F.	: C1613C3H25N3O3
Mol.Wt.	: 346.4
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Hydroxy Saxagliptin-13C3

SZ CAT No:	: SZ-S005D06
CAS No	: 1346597-23-6
Mol.F.	: C1513C3H25N3O3
Mol.Wt.	: 334.4
Inv. Status	: Custom Synthesis

Hydroxy Saxagliptin-15N,D2 Hydrochloride

SZ CAT No:	: SZ-S005D07
CAS No	: 1309934-05-1
Mol.F.	: C18H23D2N215NO3 : HCl
Mol.Wt.	: 334.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1310011-47-2 (Free base)

Hydroxy Saxagliptin-13C,D2 Hydrochloride

SZ CAT No:	: SZ-S005D08
CAS No	: 1572922-53-2
Mol.F.	: C1713CH23D2N3O3 : HCl
Mol.Wt.	: 334.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1573403-06-1 (Free base)

Saxagliptin Hydrochloride

SZ CAT No:	: SZ-S005001
CAS No	: 709031-78-7
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 361442-04-8 (Free base) ; 945667-22-1 (Hydrate) ; 1370409-28-1 (hydrochloride hydrate)

Saxagliptin O-Sulfate

SZ CAT No:	: SZ-S005002
CAS No	: 1429782-94-4
Mol.F.	: C18H25N3O5S
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

Saxagliptin N-Carboxybenzyl O-Sulfate

SZ CAT No:	: SZ-S005003
CAS No	: NA
Mol.F.	: C26H31N3O7S
Mol.Wt.	: 529.6
Inv. Status	: Custom Synthesis

Saxagliptin N-Carboxybenzyl

SZ CAT No:	: SZ-S005004
CAS No	: 1408335-73-8
Mol.F.	: C26H31N3O4
Mol.Wt.	: 449.6
Inv. Status	: Custom Synthesis

Saxagliptin EP Impurity C

SZ CAT No:	: SZ-S005005
CAS No	: 1350800-77-9
Mol.F.	: C18H24N2O3
Mol.Wt.	: 316.4
Inv. Status	: In Stock

Saxagliptin Dihydroxylated Metabolite

SZ CAT No:	: SZ-S005006
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

Boc-Saxagliptin

SZ CAT No:	: SZ-S005007
CAS No	: 709031-43-6
Mol.F.	: C23H33N3O4
Mol.Wt.	: 415.5
Inv. Status	: In Stock
Rel. CAS No	: 868839-47-8 (HCl salt)

(2S,2’R,Cis)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005008
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2R,2’S,Trans)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005009
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2R,2’R,Cis)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005010
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2R,2’R,Trans)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005011
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2R,2’S,Cis)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005012
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2S,2’S,Trans)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005013
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

(2S,2’R,Trans)-Deoxy-Saxagliptin

SZ CAT No:	: SZ-S005014
CAS No	: NA
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

3-Deoxy Saxagliptin

SZ CAT No:	: SZ-S005015
CAS No	: 361441-98-7
Mol.F.	: C18H25N3O
Mol.Wt.	: 299.4
Inv. Status	: In Stock

Saxagliptin EP Impurity B

SZ CAT No:	: SZ-S005016
CAS No	: 1496712-39-0
Mol.F.	: C18H27N3O3
Mol.Wt.	: 333.4
Inv. Status	: In Stock
Rel. CAS No	: 2173146-02-4 (HCl salt)

N-Formyl Saxagliptin

SZ CAT No:	: SZ-S005017
CAS No	: NA
Mol.F.	: C19H25N3O3
Mol.Wt.	: 343.4
Inv. Status	: In Stock

(2S,2’R,Cis)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005018
CAS No	: 1795791-40-0
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2R,2’S,Trans)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005019
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2S,2’R,Trans)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005020
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2R,2’R,Trans)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005021
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2R,2’S,Cis)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005022
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2S,2’S,Trans)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005023
CAS No	: NA
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

(2R,2’R,Cis)-7-Hydroxy-Saxagliptin

SZ CAT No:	: SZ-S005024
CAS No	: 1310011-46-1
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

Hydroxy Saxagliptin

SZ CAT No:	: SZ-S005025
CAS No	: 841302-24-7
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

Saxagliptin (S,S,S,R)-Isomer

SZ CAT No:	: SZ-S005026
CAS No	: NA
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: In Stock

(2’S,2R,Trans)-Saxagliptin

SZ CAT No:	: SZ-S005027
CAS No	: NA
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 1564266-00-7 (free base)

(2’R,2R,Cis)-Saxagliptin

SZ CAT No:	: SZ-S005028
CAS No	: NA
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: In Stock

(2’R,2R,Trans)-Saxagliptin

SZ CAT No:	: SZ-S005029
CAS No	: 1564266-03-0
Mol.F.	: C18H25N3O2
Mol.Wt.	: 315.4
Inv. Status	: Out of Stock
Rel. CAT No	: SZ-S005106 ,

(2’S,2R,Cis)-Saxagliptin

SZ CAT No:	: SZ-S005030
CAS No	: 1564265-94-6
Mol.F.	: C18H25N3O2
Mol.Wt.	: 315.4
Inv. Status	: Out of Stock, Custom Synthesis

(2S,2S’,Trans)-Saxagliptin

SZ CAT No:	: SZ-S005031
CAS No	: 1564265-96-8
Mol.F.	: C18H25N3O2
Mol.Wt.	: 315.4
Inv. Status	: Limited Stock
Rel. CAT No	: SZ-S005103 ,

(2S,2R’,Trans)-Saxagliptin (HCl salt)

SZ CAT No:	: SZ-S005032
CAS No	: NA
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: In Stock

2-Adamantanone-5-Carboxylic Acid

SZ CAT No:	: SZ-S005033
CAS No	: 56674-87-4
Mol.F.	: C11H14O3
Mol.Wt.	: 194.2
Inv. Status	: Custom Synthesis

1-Adamantylcarboxaldehyde

SZ CAT No:	: SZ-S005034
CAS No	: 2094-74-8
Mol.F.	: C11H16O
Mol.Wt.	: 164.2
Inv. Status	: In Stock

(S)-Boc-Adamantylglycine

SZ CAT No:	: SZ-S005035
CAS No	: 361441-97-6
Mol.F.	: C17H27NO4
Mol.Wt.	: 309.4
Inv. Status	: In Stock

(S)-Adamantylglycine Hydrochloride

SZ CAT No:	: SZ-S005036
CAS No	: 102502-64-7
Mol.F.	: C12H19NO2 : HCl
Mol.Wt.	: 209.3 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 95853-35-3 (Free base)

Saxagliptin EP Impurity A

SZ CAT No:	: SZ-S005037
CAS No	: 1350800-76-8
Mol.F.	: C18H25N3O2
Mol.Wt.	: 315.4
Inv. Status	: In Stock

Saxagliptin Impurity 19

SZ CAT No:	: SZ-S005038
CAS No	: 1429782-93-3
Mol.F.	: C18H25N3O3
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 20

SZ CAT No:	: SZ-S005039
CAS No	: 709031-38-9
Mol.F.	: C10H16N2O3
Mol.Wt.	: 212.3
Inv. Status	: In Stock

Saxagliptin Impurity 21

SZ CAT No:	: SZ-S005040
CAS No	: 178172-26-4
Mol.F.	: C12H19NO4
Mol.Wt.	: 241.3
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 22

SZ CAT No:	: SZ-S005041
CAS No	: 681282-72-4
Mol.F.	: C17H27NO6
Mol.Wt.	: 341.4
Inv. Status	: In Stock

Saxagliptin Impurity 23

SZ CAT No:	: SZ-S005042
CAS No	: 361442-00-4
Mol.F.	: C17H27NO5
Mol.Wt.	: 325.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 2460207-00-3 (Na salt)

Saxagliptin Impurity 24

SZ CAT No:	: SZ-S005043
CAS No	: 1334321-39-9
Mol.F.	: C17H27NO5
Mol.Wt.	: 325.4
Inv. Status	: In Stock

Nα-Boc-L-Ornithine

SZ CAT No:	: SZ-S005044
CAS No	: 21887-64-9
Mol.F.	: C10H20N2O4
Mol.Wt.	: 232.3
Inv. Status	: In Stock

Saxagliptin Impurity 25

SZ CAT No:	: SZ-S005045
CAS No	: 197142-36-2
Mol.F.	: C11H17NO4
Mol.Wt.	: 227.3
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 26

SZ CAT No:	: SZ-S005046
CAS No	: 1564266-54-1
Mol.F.	: C11H18N2O3
Mol.Wt.	: 226.3
Inv. Status	: In Stock

Saxagliptin Impurity 27

SZ CAT No:	: SZ-S005047
CAS No	: 1445592-86-8
Mol.F.	: C11H18N2O3
Mol.Wt.	: 226.3
Inv. Status	: In Stock

Saxagliptin Impurity 28

SZ CAT No:	: SZ-S005048
CAS No	: 1564266-79-0
Mol.F.	: C11H18N2O3
Mol.Wt.	: 226.3
Inv. Status	: Custom Synthesis

Saxagliptin keto Impurity

SZ CAT No:	: SZ-S005049
CAS No	: 2173146-35-3
Mol.F.	: C18H23N3O2 : HCl
Mol.Wt.	: 313.4 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2173146-34-2 (free base)

Saxaglipti-N-BOC-Amide

SZ CAT No:	: SZ-S005050
CAS No	: 361440-67-7
Mol.F.	: C11H18N2O3
Mol.Wt.	: 226.3
Inv. Status	: In Stock

Saxagliptin Impurity 29

SZ CAT No:	: SZ-S005051
CAS No	: NA
Mol.F.	: C22H28N2O6
Mol.Wt.	: 416.5
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 30

SZ CAT No:	: SZ-S005052
CAS No	: NA
Mol.F.	: C22H27N3O5
Mol.Wt.	: 413.5
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 31

SZ CAT No:	: SZ-S005053
CAS No	: NA
Mol.F.	: C30H45N3O12
Mol.Wt.	: 639.7
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 32

SZ CAT No:	: SZ-S005054
CAS No	: NA
Mol.F.	: C19H30N2O2
Mol.Wt.	: 318.5
Inv. Status	: Custom Synthesis

R Isomer Of Saxagliptin Amide

SZ CAT No:	: SZ-S005055
CAS No	: 1133811-49-0
Mol.F.	: C6H10N2O
Mol.Wt.	: 126.2
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 1312338-82-1 (methanesulfonate)

Saxagliptin Amide

SZ CAT No:	: SZ-S005056
CAS No	: 361440-68-8
Mol.F.	: C6H10N2O
Mol.Wt.	: 126.2
Inv. Status	: In Stock
Rel. CAS No	: 709031-39-0 (HCl salt) ; 709031-45-8 (mesylate salt)

Saxagliptin Impurity 33

SZ CAT No:	: SZ-S005057
CAS No	: 1564266-73-4
Mol.F.	: C6H10N2O
Mol.Wt.	: 126.2
Inv. Status	: Limited Stock

Saxagliptin Impurity 34

SZ CAT No:	: SZ-S005058
CAS No	: NA
Mol.F.	: C22H28N2O6
Mol.Wt.	: 416.5
Inv. Status	: Custom Synthesis

Saxagliptin Hydrate

SZ CAT No:	: SZ-S005059
CAS No	: 945667-22-1
Mol.F.	: C18H25N3O2 : H2O
Mol.Wt.	: 315.4 : 18.0
Inv. Status	: In Stock
Rel. CAS No	: 709031-78-7 (HCl salt) ; 361442-04-8 (Free base)

Saxagliptin C2-Epimer (Oxalate Salt)

SZ CAT No:	: SZ-S005060
CAS No	: NA
Mol.F.	: C17H25N3O2 : C2H2O4
Mol.Wt.	: 303.4 : 90.0
Inv. Status	: Custom Synthesis

(2’S,2R,trans)-Saxagliptin Isopropylate

SZ CAT No:	: SZ-S005061
CAS No	: NA
Mol.F.	: C18H25N3O2 : C3H8O : HCl
Mol.Wt.	: 315.4 : 60.1 : 36.5
Inv. Status	: Limited Stock

Saxagliptin Impurity 35

SZ CAT No:	: SZ-S005063
CAS No	: 1564266-70-1
Mol.F.	: C6H10N2O : CH4O3S
Mol.Wt.	: 126.2 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 700376-57-4 (free base) ; 700376-58-5 (TFA salt) ; 1867272-80-7 (HCl salt)

Saxagliptin Impurity 36

SZ CAT No:	: SZ-S005064
CAS No	: 1849427-12-8
Mol.F.	: C7H12N2O
Mol.Wt.	: 140.2
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 37

SZ CAT No:	: SZ-S005065
CAS No	: 1621530-36-6
Mol.F.	: C14H23NO3
Mol.Wt.	: 253.3
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 38 (Hydrate)

SZ CAT No:	: SZ-S005066
CAS No	: NA
Mol.F.	: C12H19NO3 : H2O
Mol.Wt.	: 225.3 : 18.0
Inv. Status	: In Stock
Rel. CAS No	: 709031-29-8 (free base) ; 865999-64-0 (HCl salt) ; 1471093-87-4 (TFA salt)

3-Deshydroxy 3-Keto Saxagliptin

SZ CAT No:	: SZ-S005067
CAS No	: 2173146-34-2
Mol.F.	: C18H23N3O2
Mol.Wt.	: 313.4
Inv. Status	: Under Synthesis
Rel. CAS No	: 2173146-35-3 (HCl salt)

Saxagliptin Impurity 39

SZ CAT No:	: SZ-S005068
CAS No	: 361441-95-4
Mol.F.	: C20H26N2O
Mol.Wt.	: 310.4
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 40

SZ CAT No:	: SZ-S005069
CAS No	: 361441-96-5
Mol.F.	: C20H27NO3 : HCl
Mol.Wt.	: 329.4 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 769912-51-8 (free base)

Saxagliptin Impurity 41

SZ CAT No:	: SZ-S005070
CAS No	: 865999-67-3
Mol.F.	: C6H8N2 : HCl
Mol.Wt.	: 108.1 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 866083-42-3 (free base)

Saxagliptin Impurity 42

SZ CAT No:	: SZ-S005071
CAS No	: 1312338-82-1
Mol.F.	: C6H10N2O : CH4O3S
Mol.Wt.	: 126.2 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 1133811-49-0 (free base)

Saxagliptin Impurity 43

SZ CAT No:	: SZ-S005072
CAS No	: 1564266-74-5
Mol.F.	: C6H10N2O : CH4O3S
Mol.Wt.	: 126.2 : 96.1
Inv. Status	: In Stock
Rel. CAS No	: 1564266-73-4 (free base)

Saxagliptin Impurity 44

SZ CAT No:	: SZ-S005073
CAS No	: 194594-23-5
Mol.F.	: C12H21NO5
Mol.Wt.	: 259.3
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 45

SZ CAT No:	: SZ-S005074
CAS No	: 2173146-31-9
Mol.F.	: C17H25NO5
Mol.Wt.	: 323.4
Inv. Status	: In Stock

Saxagliptin Nitroso Impurity 4

SZ CAT No:	: SZ-S005075
CAS No	: NA
Mol.F.	: C6H7N3O
Mol.Wt.	: 137.1
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 38

SZ CAT No:	: SZ-S005076
CAS No	: 709031-29-8
Mol.F.	: C12H19NO3
Mol.Wt.	: 225.3
Inv. Status	: In Stock
Rel. CAS No	: 865999-64-0 (HCl salt) ; 1471093-87-4 (TFA salt)

Saxagliptin Impurity 54

SZ CAT No:	: SZ-S005077
CAS No	: 197142-34-0
Mol.F.	: C37H39N3O2
Mol.Wt.	: 557.7
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 55

SZ CAT No:	: SZ-S005078
CAS No	: NA
Mol.F.	: C37H39N3O
Mol.Wt.	: 541.7
Inv. Status	: Custom Synthesis

Saxagliptin Impurity 56

SZ CAT No:	: SZ-S005079
CAS No	: 1669461-40-8
Mol.F.	: C37H39N3O2
Mol.Wt.	: 557.7
Inv. Status	: Custom Synthesis

Saxagliptin RRRR Isomer

SZ CAT No:	: SZ-S005080
CAS No	: NA
Mol.F.	: C18H25N3O2 : HCl
Mol.Wt.	: 315.4 : 36.5
Inv. Status	: Limited Stock
Rel. CAS No	: 1564265-95-7 (free base)

Saxagliptin Hydrochloride Dihydrate

SZ CAT No:	: SZ-S005081
CAS No	: 1073057-20-1
Mol.F.	: C18H25N3O2 : HCl : 2(H2O)
Mol.Wt.	: 315.4 : 36.5 : 2(18.0)
Inv. Status	: In Stock
Rel. CAS No	: 709031-78-7 (HCl salt) ; 361442-04-8 (Free base) ; 945667-22-1 (Hydrate)

Saxagliptin Impurity 56

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