S-(+)-Manidipine D4

SZ CAT No:	SZ-M057D02
CAS No	1217836-12-8
Mol.F.	C35H34D4N4O6
Mol.Wt.	614.7
Inv. Status	Custom Synthesis

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Chemical Name: 3-(2-(4-benzhydrylpiperazin-1-yl)ethyl-1,1,2,2-d4) 5-methyl (S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C([C@@H](C1=CC([N](=O)=O)=CC=C1)C(C(OC)=O)=C(C)N2)=C2C)OC([2H])([2H])C([2H])([2H])N3CCN(C(C4=CC=CC=C4)C5=CC=CC=C5)CC3

Quantitative Analysis of Manidipine Dihydrochloride in Bulk and Synthetic Mixtures by Visible Spectrophotometry
Lakshmi Sivasubramanian, Manikandan K, Venkatesan M, Lakshmi KS
Manikandan, et al. J Young Pharm. 2009;1(2):175-179

Stability indicating HPTLC method for quantitative estimation of manidipine sihydrochloride API
Santhana Lakshmi Karunanidhi, Lakshmi Sivasubramanian and Manikandan Krishnan
European Journal of Chemistry 2 (1) (2011) 113‐116

S-(+)-Manidipine D4 is chemically 3-(2-(4-benzhydrylpiperazin-1-yl)ethyl-1,1,2,2-d4) 5-methyl (S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate. S-(+)-Manidipine D4 is supplied with detailed characterization data compliant with regulatory guideline. S-(+)-Manidipine D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Manidipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

S-(+)-Manidipine D4

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Inv. Status	: Custom Synthesis

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