Ritonavir EP Impurity B

SZ CAT No:	SZ-R003003
CAS No	765875-58-9
Mol.F.	C28H36N4O4S
Mol.Wt.	524.7
Inv. Status	In Stock
Rel. CAS No	165315-97-9 (HCl salt)

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Chemical Name: Thiazol-5-yl-methyl [(1S,2S,4S)-4-[[(2S)-2-amino-3-methylbutanoyl]amino]-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate (as per EP)

Synonym: N-Deacylvaline Ritonavir

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(OCC1=CN=CS1)N[C@H]([C@@H](O)C[C@@H](NC([C@@H](N)C(C)C)=O)CC2=CC=CC=C2)CC3=CC=CC=C3

Development and validation of stability-indicating UPLC-TUV method for simultaneous estimation of darunavir and ritonavir in bulk and tablet dosage form
By Kamalakannan, Dhanabalan; AnandaThangadurai, Subramaniam
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 611-619

Stability indicating method development and validation for simultaneous estimation of Lopinavir and Ritonavir by using RP-HPLC
By Raghu, P. S.
From World Journal of Pharmaceutical Research (2018), 7(3), 1750-1757

Stability-indicating RP-HPLC method for simultaneous quantification of ombitasvir, paritaprevir and ritonavir in tablet dosage form
By Kuna, Mangamma; Dannana, Gowri Sankar
From Asian Journal of Chemistry (2018), 30(6), 1277-1283

Ritonavir EP Impurity B is chemically Thiazol-5-yl-methyl [(1S,2S,4S)-4-[[(2S)-2-amino-3-methylbutanoyl]amino]-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate (as per EP). It is also known as N-Deacylvaline Ritonavir. Ritonavir EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Ritonavir EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ritonavir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Ritonavir EP Impurity B

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Mol.F.	: C28H36N4O4S
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Rel. CAS No	: 165315-97-9 (HCl salt)

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Ritonavir EP Impurity A

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Ritonavir EP Impurity D

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Ritonavir EP Impurity E

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Mol.F.	: C37H48N6O6S2
Mol.Wt.	: 736.9
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Ritonavir EP Impurity F

SZ CAT No:	: SZ-R003007
CAS No	: 1010809-61-6
Mol.F.	: C29H34N4O5S
Mol.Wt.	: 550.7
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Ritonavir EP Impurity G

SZ CAT No:	: SZ-R003008
CAS No	: 2034136-66-6
Mol.F.	: C37H48N6O7S2
Mol.Wt.	: 752.9
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Ritonavir EP Impurity H

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Mol.F.	: C30H32N4O6S
Mol.Wt.	: 576.7
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Ritonavir EP Impurity I

SZ CAT No:	: SZ-R003010
CAS No	: 165315-26-4
Mol.F.	: C36H46N6O5S2
Mol.Wt.	: 706.9
Inv. Status	: Limited Stock

Ritonavir EP Impurity J

SZ CAT No:	: SZ-R003011
CAS No	: 162849-95-8
Mol.F.	: C28H35N3O5S
Mol.Wt.	: 525.7
Inv. Status	: In Stock

Ritonavir EP Impurity K

SZ CAT No:	: SZ-R003012
CAS No	: 1010809-39-8
Mol.F.	: C28H35N3O5S
Mol.Wt.	: 525.7
Inv. Status	: In Stock

Ritonavir EP Impurity L

SZ CAT No:	: SZ-R003013
CAS No	: 256328-82-2
Mol.F.	: C33H43N5O4S
Mol.Wt.	: 605.8
Inv. Status	: In Stock

Ritonavir EP Impurity M

SZ CAT No:	: SZ-R003014
CAS No	: NA
Mol.F.	: C18H31N3O3S
Mol.Wt.	: 369.5
Inv. Status	: In Stock

Ritonavir EP Impurity N

SZ CAT No:	: SZ-R003015
CAS No	: 202816-62-4
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: Out of Stock

Ritonavir EP Impurity O

SZ CAT No:	: SZ-R003016
CAS No	: 1414933-81-5
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir EP Impurity P

SZ CAT No:	: SZ-R003017
CAS No	: 2804644-96-8
Mol.F.	: C47H52N6O7S2
Mol.Wt.	: 877.1
Inv. Status	: In Stock

Ritonavir EP Impurity Q

SZ CAT No:	: SZ-R003018
CAS No	: 1414933-82-6
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir EP Impurity R

SZ CAT No:	: SZ-R003019
CAS No	: 1414933-80-4
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir EP Impurity S

SZ CAT No:	: SZ-R003020
CAS No	: 2084828-53-3
Mol.F.	: C52H61N7O8S2
Mol.Wt.	: 976.2
Inv. Status	: In Stock

Ritonavir EP Impurity T

SZ CAT No:	: SZ-R003021
CAS No	: 869368-48-9
Mol.F.	: C46H66N8O5S2
Mol.Wt.	: 875.2
Inv. Status	: In Stock

Ritonavir EP Impurity U

SZ CAT No:	: SZ-R003022
CAS No	: NA
Mol.F.	: C51H69N9O7S3
Mol.Wt.	: 1016.3
Inv. Status	: In Stock

Ritonavir 4R Epimer

SZ CAT No:	: SZ-R003023
CAS No	: 1798014-18-2
Mol.F.	: C37H48N4O5
Mol.Wt.	: 628.8
Inv. Status	: In Stock

Ritonavir Enantiomer

SZ CAT No:	: SZ-R003024
CAS No	: 2872582-94-8
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 721.0
Inv. Status	: In Stock

Ritonavir Geo-Isomer

SZ CAT No:	: SZ-R003025
CAS No	: NA
Mol.F.	: C37H48N6O5S2 : HCl
Mol.Wt.	: 720.9 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 959315-21-0 (free base)

Ritonavir Isoleucine Analog

SZ CAT No:	: SZ-R003026
CAS No	: NA
Mol.F.	: C38H50N6O5S2
Mol.Wt.	: 735.0
Inv. Status	: In Stock

Ritonavir Impurity J + K (Mixture of Boc-Amino Alcohol and Isobutoxy Carbonyl Amino Alcohol

SZ CAT No:	: SZ-R003027
CAS No	: NA
Mol.F.	: C28H35N3O5S : C28H35N3O5S
Mol.Wt.	: 525.7 : 525.7
Inv. Status	: In Stock

Ritonavir-Glycerol carbamate Analog

SZ CAT No:	: SZ-R003028
CAS No	: 1010809-54-7
Mol.F.	: C32H42N4O8S
Mol.Wt.	: 642.8
Inv. Status	: In Stock

Ritonavir Impurity V

SZ CAT No:	: SZ-R003031
CAS No	: NA
Mol.F.	: C38H50N6O4S2
Mol.Wt.	: 719.0
Inv. Status	: Custom Synthesis

4-Nitrophenyl Chloroformate

SZ CAT No:	: SZ-R003032
CAS No	: 7693-46-1
Mol.F.	: C7H4ClNO4
Mol.Wt.	: 201.6
Inv. Status	: In Stock
Rel. CAS No	: 2253682-86-7 (HCl salt)

(5-Thiazolyl)Methyl)-(4-Nitrophenyl) Carbohydrate

SZ CAT No:	: SZ-R003033
CAS No	: 144163-97-3
Mol.F.	: C11H8N2O5S
Mol.Wt.	: 280.3
Inv. Status	: In Stock, 3-4 days for Dispatch
Rel. CAS No	: 154212-59-6 (HCl salt)

Ritonavir D6

SZ CAT No:	: SZ-R003D01
CAS No	: 1217720-20-1
Mol.F.	: C37H42D6N6O5S2
Mol.Wt.	: 727.0
Inv. Status	: Custom Synthesis

Ritonavir Impurity 3

SZ CAT No:	: SZ-R003034
CAS No	: 1283151-18-7
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 4

SZ CAT No:	: SZ-R003035
CAS No	: 1414933-85-9
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: Out of Stock

Ritonavir Impurity 5

SZ CAT No:	: SZ-R003036
CAS No	: 1414933-94-0
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 6

SZ CAT No:	: SZ-R003037
CAS No	: 220887-41-2
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 7

SZ CAT No:	: SZ-R003038
CAS No	: 1414933-89-3
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 8

SZ CAT No:	: SZ-R003039
CAS No	: 1414933-91-7
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 9

SZ CAT No:	: SZ-R003040
CAS No	: 1414933-83-7
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir Impurity 10

SZ CAT No:	: SZ-R003041
CAS No	: 144163-85-9
Mol.F.	: C23H32N2O3
Mol.Wt.	: 384.5
Inv. Status	: In Stock

Ritonavir D8

SZ CAT No:	: SZ-R003D02
CAS No	: NA
Mol.F.	: C37H40D8N6O5S2
Mol.Wt.	: 729.0
Inv. Status	: Custom Synthesis

O-Acetyl Ritonavir

SZ CAT No:	: SZ-R003042
CAS No	: 183246-46-0
Mol.F.	: C14H23N3O3S
Mol.Wt.	: 313.4
Inv. Status	: In Stock

Ritonavir Impurity 11

SZ CAT No:	: SZ-R003043
CAS No	: 1414934-16-9
Mol.F.	: C14H23N3O3S
Mol.Wt.	: 313.4
Inv. Status	: In Stock

Ritonavir Impurity 12

SZ CAT No:	: SZ-R003044
CAS No	: 241486-86-2
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir Impurity 13

SZ CAT No:	: SZ-R003045
CAS No	: NA
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir Impurity 14

SZ CAT No:	: SZ-R003046
CAS No	: 1797984-48-5
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Ritonavir Impurity 15

SZ CAT No:	: SZ-R003047
CAS No	: NA
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: In Stock

Mixture of ureidovaline and N-deacylvaline ritonavir

SZ CAT No:	: SZ-R003050
CAS No	: NA
Mol.F.	: C14H23N3O3S : C28H36N4O4S
Mol.Wt.	: 313.4 : 524.7
Inv. Status	: In Stock

Ritonavir Ethyl Carbamate Analog

SZ CAT No:	: SZ-R003051
CAS No	: NA
Mol.F.	: C31H40N4O6S
Mol.Wt.	: 596.7
Inv. Status	: In Stock

Des-Isopropylthiazolyl Ritonavir

SZ CAT No:	: SZ-R003052
CAS No	: 176655-57-5
Mol.F.	: C30H39N5O5S
Mol.Wt.	: 581.7
Inv. Status	: Custom Synthesis

Ritonavir EP Impurity B (HCl)

SZ CAT No:	: SZ-R003053
CAS No	: 165315-97-9
Mol.F.	: C28H36N4O4S : HCl
Mol.Wt.	: 524.7 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 765875-58-9 (free base)

Ritonavir Impurity 16

SZ CAT No:	: SZ-R003054
CAS No	: NA
Mol.F.	: C42H57N7O6S2
Mol.Wt.	: 820.1
Inv. Status	: Custom Synthesis

Ritonavir Impurity 17

SZ CAT No:	: SZ-R003055
CAS No	: 1004316-56-6
Mol.F.	: C28H30N4O4S2
Mol.Wt.	: 550.7
Inv. Status	: Custom Synthesis

Ritonavir Impurity 18

SZ CAT No:	: SZ-R003056
CAS No	: 1370406-80-6
Mol.F.	: C23H27N3O2S : HCl
Mol.Wt.	: 409.5 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1004316-78-2 (free base)

Ritonavir Hydroxy impurity

SZ CAT No:	: SZ-R003057
CAS No	: 2519851-81-9
Mol.F.	: C14H23N3O4S
Mol.Wt.	: 329.4
Inv. Status	: Custom Synthesis

Ritonavir Hydrogen Peroxide Impurity

SZ CAT No:	: SZ-R003058
CAS No	: NA
Mol.F.	: C14H23N3O5S
Mol.Wt.	: 345.4
Inv. Status	: Custom Synthesis

Ritonavir Impurity 19

SZ CAT No:	: SZ-R003059
CAS No	: 22050-72-2
Mol.F.	: C7H9NS
Mol.Wt.	: 139.2
Inv. Status	: Custom Synthesis

Ritonavir Impurity 20

SZ CAT No:	: SZ-R003060
CAS No	: NA
Mol.F.	: C22H26N4O5S
Mol.Wt.	: 458.5
Inv. Status	: Custom Synthesis

Ritonavir Amino Alcohol Urea Derivative

SZ CAT No:	: SZ-R003061
CAS No	: NA
Mol.F.	: C47H50N6O7S2
Mol.Wt.	: 875.1
Inv. Status	: Custom Synthesis

Ritonavir Impurity 21

SZ CAT No:	: SZ-R003062
CAS No	: NA
Mol.F.	: C37H48N6O5S2
Mol.Wt.	: 720.9
Inv. Status	: Custom Synthesis

N-Phenoxycarbonyl-L-valine

SZ CAT No:	: SZ-R003063
CAS No	: 126147-70-4
Mol.F.	: C12H15NO4
Mol.Wt.	: 237.3
Inv. Status	: In Stock
Rel. CAS No	: 201409-22-5 (sodium salt)

Ritonavir Diamino Alcohol Impurity

SZ CAT No:	: SZ-R003064
CAS No	: 144163-44-0
Mol.F.	: C18H24N2O
Mol.Wt.	: 284.4
Inv. Status	: Custom Synthesis

Ritonavir Impurity 22

SZ CAT No:	: SZ-R003065
CAS No	: 2470440-54-9
Mol.F.	: C15H23N3S2
Mol.Wt.	: 309.5
Inv. Status	: Custom Synthesis

Ritonavir Impurity 23

SZ CAT No:	: SZ-R003066
CAS No	: 1004316-34-0
Mol.F.	: C13H21N3O3S
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

Ritonavir EP Impurity B

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