Ribociclib Impurity 17

SZ CAT No:	SZ-R035031
CAS No	NA
Mol.F.	C22H27N7O2
Mol.Wt.	421.5
Inv. Status	Custom Synthesis

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Chemical Name: Methyl 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(OC)C1=CC2=CN=C(NC3=CC=C(N4CCNCC4)C=N3)N=C2N1C5CCCC5

Ribociclib Impurity 17 is chemically Methyl 7-cyclopentyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate. Ribociclib Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Ribociclib Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ribociclib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Ribociclib

SZ CAT No:	: SZ-R035001
CAS No	: 1211441-98-3
Mol.F.	: C23H30N8O
Mol.Wt.	: 434.6
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib Succinate

SZ CAT No:	: SZ-R035002
CAS No	: 1374639-75-4
Mol.F.	: C23H30N8O : C4H6O4
Mol.Wt.	: 434.6 : 118.1
Inv. Status	: In Stock
Rel. CAS No	: 1211443-80-9 (HCl salt) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1211441-98-3 (free base)

Ribociclib HCl

SZ CAT No:	: SZ-R035003
CAS No	: 1211443-80-9
Mol.F.	: C23H30N8O : HCl
Mol.Wt.	: 434.5 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1211441-98-3 (free base) ; 2209917-73-5 (HBr salt) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib N-Desmethyl Metabolite

SZ CAT No:	: SZ-R035004
CAS No	: NA
Mol.F.	: C22H28N8O : HCl
Mol.Wt.	: 420.5 : 36.5
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 1211441-59-6 (Free base)

Ribociclib N,N-DiDesmethyl Metabolite

SZ CAT No:	: SZ-R035005
CAS No	: NA
Mol.F.	: C21H26N8O
Mol.Wt.	: 406.0
Inv. Status	: Custom Synthesis

Ribociclib Chloro Amide Impurity

SZ CAT No:	: SZ-R035006
CAS No	: 1211443-61-6
Mol.F.	: C14H17ClN4O
Mol.Wt.	: 292.8
Inv. Status	: In Stock

Ribociclib Chloro Hydroxy Impurity

SZ CAT No:	: SZ-R035007
CAS No	: 1374639-77-6
Mol.F.	: C12H14ClN3O
Mol.Wt.	: 251.7
Inv. Status	: In Stock

Ribociclib-d6

SZ CAT No:	: SZ-R035D01
CAS No	: 1328934-40-2
Mol.F.	: C23H24D6N8O
Mol.Wt.	: 440.6
Inv. Status	: In Stock

Ribociclib Acid Impurity

SZ CAT No:	: SZ-R035008
CAS No	: NA
Mol.F.	: C21H25N7O2 : 2(HCl)
Mol.Wt.	: 407.5 : 2(36.5)
Inv. Status	: In Stock
Rel. CAS No	: 2762182-61-4 (free base)

Ribociclib pyridine N-oxide

SZ CAT No:	: SZ-R035009
CAS No	: NA
Mol.F.	: C23H30N8O2 : HCl
Mol.Wt.	: 450.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2069953-39-3 (Free base)

Ribociclib Impurity 3

SZ CAT No:	: SZ-R035010
CAS No	: NA
Mol.F.	: C14H18N4O2
Mol.Wt.	: 274.3
Inv. Status	: Out of Stock

Ribociclib Impurity 4

SZ CAT No:	: SZ-R035011
CAS No	: 3060653-14-4
Mol.F.	: C27H34N8O4
Mol.Wt.	: 534.6
Inv. Status	: In Stock

Ribociclib Impurity 5

SZ CAT No:	: SZ-R035012
CAS No	: NA
Mol.F.	: C21H25N7O3 : 2HCl
Mol.Wt.	: 423.5 : 2(36.5)
Inv. Status	: Out of Stock, Custom Synthesis

Ribociclib-d8

SZ CAT No:	: SZ-R035D02
CAS No	: 2167898-24-8
Mol.F.	: C23H22D8N8O
Mol.Wt.	: 442.6
Inv. Status	: Custom Synthesis

Ribociclib N-Oxide Impurity 1

SZ CAT No:	: SZ-R035013
CAS No	: 2514753-27-4
Mol.F.	: C23H30N8O2
Mol.Wt.	: 450.5
Inv. Status	: Custom Synthesis

Ribociclib N-Oxide Impurity 2 (Hemihydrate)

SZ CAT No:	: SZ-R035014
CAS No	: NA
Mol.F.	: C23H30N8O2 : 1/2(H2O)
Mol.Wt.	: 450.5 : 1/2(18.0)
Inv. Status	: Out of Stock
Rel. CAS No	: 2470164-21-5 (Free base)

N-Formyl Ribociclib (HCl salt)

SZ CAT No:	: SZ-R035015
CAS No	: NA
Mol.F.	: C24H30N8O2 : HCl
Mol.Wt.	: 462.6 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 2460732-08-3 (free base)

Ribociclib Impurity 8

SZ CAT No:	: SZ-R035016
CAS No	: 1374639-76-5
Mol.F.	: C12H14ClN3O
Mol.Wt.	: 251.7
Inv. Status	: In Stock

Ribociclib Impurity 9

SZ CAT No:	: SZ-R035017
CAS No	: 1211443-55-8
Mol.F.	: C12H12ClN3O
Mol.Wt.	: 249.7
Inv. Status	: In Stock

Ribociclib N-Oxide Impurity 2 (Dihydrochloride salt)

SZ CAT No:	: SZ-R035018
CAS No	: NA
Mol.F.	: C23H30N8O2 : 2(HCl)
Mol.Wt.	: 450.5 : 2(36.5)
Inv. Status	: Out of Stock, Custom Synthesis
Rel. CAS No	: 2470164-21-5 (Free base)

Ribociclib Hydrobromide

SZ CAT No:	: SZ-R035019
CAS No	: 2209917-73-5
Mol.F.	: C23H30N8O : HBr
Mol.Wt.	: 434.6 : 80.9
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1211443-80-9 (HCl salt) ; 1211441-98-3 (free base) ; 2209917-76-8 (Sulfate) ; 1374639-75-4 (Succinate)

Ribociclib Nitroso Impurity 1

SZ CAT No:	: SZ-R035022
CAS No	: NA
Mol.F.	: C23H29N9O2
Mol.Wt.	: 463.5
Inv. Status	: In Stock

Ribociclib Nitroso Impurity 2

SZ CAT No:	: SZ-R035023
CAS No	: NA
Mol.F.	: C23H28N10O3
Mol.Wt.	: 492.5
Inv. Status	: Inquire

Ribociclib Nitroso Impurity 3

SZ CAT No:	: SZ-R035024
CAS No	: NA
Mol.F.	: C23H29N9O2
Mol.Wt.	: 463.5
Inv. Status	: Inquire

Ribociclib Impurity 11

SZ CAT No:	: SZ-R035025
CAS No	: NA
Mol.F.	: C23H30N8O3
Mol.Wt.	: 466.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 12

SZ CAT No:	: SZ-R035026
CAS No	: 2460738-27-4
Mol.F.	: C21H28N8O
Mol.Wt.	: 408.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 13

SZ CAT No:	: SZ-R035027
CAS No	: 2460734-07-8
Mol.F.	: C23H30N8O2
Mol.Wt.	: 450.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 14

SZ CAT No:	: SZ-R035028
CAS No	: NA
Mol.F.	: C23H30N8O2
Mol.Wt.	: 450.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 16

SZ CAT No:	: SZ-R035030
CAS No	: NA
Mol.F.	: C22H28N8O2
Mol.Wt.	: 436.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 17

SZ CAT No:	: SZ-R035031
CAS No	: NA
Mol.F.	: C22H27N7O2
Mol.Wt.	: 421.5
Inv. Status	: Custom Synthesis

Ribociclib Impurity 18

SZ CAT No:	: SZ-R035032
CAS No	: 1823404-28-9
Mol.F.	: C9H11BrClN3
Mol.Wt.	: 276.6
Inv. Status	: Custom Synthesis

Ribociclib Impurity 19

SZ CAT No:	: SZ-R035033
CAS No	: 1214279-37-4
Mol.F.	: C9H11Cl2N3
Mol.Wt.	: 232.1
Inv. Status	: Custom Synthesis

Ribociclib Impurity 20

SZ CAT No:	: SZ-R035034
CAS No	: 2481084-18-6
Mol.F.	: C9H11Br2N3
Mol.Wt.	: 321.0
Inv. Status	: Custom Synthesis

Ribociclib Impurity 21

SZ CAT No:	: SZ-R035035
CAS No	: NA
Mol.F.	: C26H30ClN7O2
Mol.Wt.	: 508.0
Inv. Status	: Custom Synthesis

Ribociclib Impurity 22

SZ CAT No:	: SZ-R035036
CAS No	: NA
Mol.F.	: C24H27ClN6O2
Mol.Wt.	: 467.0
Inv. Status	: Custom Synthesis

Ribociclib Impurity 23

SZ CAT No:	: SZ-R035037
CAS No	: NA
Mol.F.	: C15H17N3O2
Mol.Wt.	: 271.3
Inv. Status	: Custom Synthesis

Ribociclib Impurity 24

SZ CAT No:	: SZ-R035038
CAS No	: NA
Mol.F.	: C24H27ClN6O2
Mol.Wt.	: 467.0
Inv. Status	: Custom Synthesis

Ribociclib Impurity 25

SZ CAT No:	: SZ-R035039
CAS No	: NA
Mol.F.	: C24H27ClN6O2
Mol.Wt.	: 467.0
Inv. Status	: Custom Synthesis

Ribociclib Impurity 26

SZ CAT No:	: SZ-R035040
CAS No	: 120613-50-5
Mol.F.	: C10H6Cl2N4O
Mol.Wt.	: 269.1
Inv. Status	: Custom Synthesis

Ribociclib Impurity 27

SZ CAT No:	: SZ-R035041
CAS No	: 1298101-40-2
Mol.F.	: C4HBr3N2
Mol.Wt.	: 316.8
Inv. Status	: Custom Synthesis

Ribociclib Impurity 28

SZ CAT No:	: SZ-R035042
CAS No	: 733039-20-8
Mol.F.	: C9H11BrClN3
Mol.Wt.	: 276.6
Inv. Status	: In Stock

Ribociclib Impurity 17

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