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Pyrimethamine EP Impurity B

SZ CAT No SZ-P068003
CAS No 3275-44-3
Mol.F. C11H11ClN4
Mol.Wt. 234.7
Inv. Status In Stock


Chemical Name: 5-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine

Synonym: 5-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine

Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets
Yonah H.Mwalwisi, Ludwig Hoellein, Eliangiringa Kaale, UlrikeHolzgrabe
Journal of Pharmaceutical and Biomedical Analysis Volume 129, 10 September 2016, Pages 558-570
 
Development of 2,4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant Plasmodium falciparum
Bongkoch Tarnchompoo, Chawanee Sirichaiwat, Worrapong Phupong, Chakapong Intaraudom, Worachart Sirawaraporn, Sumalee Kamchonwongpaisan, Jarunee Vanichtanankul, Yodhathai Thebtaranonth, and Yongyuth Yuthavong
J. Med. Chem. 2002, 45, 6, 1244–1252
 
Validated HPTLC Method for Simultaneous Analysis of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage Forms
S. Meena and S. M. Sandhya
Hindawi Publishing Corporation Journal of Chemistry Volume 2013, Article ID 698490, 6 pages