Paroxetine EP Impurity E

SZ CAT No:	SZ-P012006
CAS No	72473-26-8
Mol.F.	C19H20FNO3
Mol.Wt.	329.4
Inv. Status	Custom Synthesis
Shipping Condition	Ambient Temperature

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Chemical Name: (3RS,4RS)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine

Synonym: cis-paroxetine ; Paroxetine USP Related Compound D

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC1=CC=C([C@@]2([H])[C@](COC(C=C3)=CC4=C3OCO4)([H])CNCC2)C=C1

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolff
Journal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089

An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig
Cryst. Growth Des. 2014, 14, 8, 3774–3782

Determination of residual solvents in paroxetine by headspace gas chromatography
abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy
Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155

Spectral Characterization of Degradation Impurities of Paroxetine Hydrochloride Hemihydrate
nirmala munigela, j. moses babu , anjaneyulu yerramilli , naveen kumar kolla , vyas krishnamurthy, vijay vittal mathad
Sci Pharm. 2008; 76; 653–661.

Paroxetine EP Impurity E is chemically (3RS,4RS)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine. It is also known as cis-paroxetine ; Paroxetine USP Related Compound D. Paroxetine EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Paroxetine EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paroxetine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Paroxetine EP Impurity E

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Inv. Status	: In Stock

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Mol.F.	: C7H6O3
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Mol.F.	: C19H20FNO3 : HCl
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Inv. Status	: Out of Stock, Custom Synthesis

SZ CAT No:	: SZ-P012006
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Inv. Status	: Custom Synthesis

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Mol.F.	: C19H20FNO3 : HCl : 1/2(H2O)
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Inv. Status	: In Stock

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Inv. Status	: In Stock

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Mol.F.	: C19H20FNO3 : 1/2(H2O)
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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis