Omeprazole EP Impurity E

SZ CAT No:	SZ-O004006
CAS No	176219-04-8
Mol.F.	C17H19N3O4S
Mol.Wt.	361.4
Inv. Status	In Stock

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Chemical Name: 4-Methoxy-2-[[(RS)-(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethylpyridine 1-oxide (as per EP)

Synonym: Omeprazole USP Related Compound E

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC1=CC=C2C(NC(S(CC3=C(C)C(OC)=C(C)C=[N+]3[O-])=O)=N2)=C1

Elemental impurities analysis in name-brand and generic omeprazole drug samples
Fernanda C. Pinheiro, Ariane I.Barros, Joaquim A.Nóbrega
Heliyon Volume 6, Issue 2, February 2020, e03359

Development of a validated RP-HPLC method for separation and determination of process-related impurities of omeprazole in bulk drugs
cristina iuga, marius bojiţă, sorin e. leucuţa
farmacia, 2009, vol. 57, 5

Low Level Quantification of Potential Genotoxic Impurity in Omeprazole Drug Substance by UPLC
Vinay Kumar Patcha , Susheela Bhai Gajbhiye , Vundavilli Jagadeesh Kumar , Ray UK ,Pavan Kumar KSR , Sreenivas N
Der Pharma Chemica, 2017, 9(15):72-76

Omeprazole EP Impurity E is chemically 4-Methoxy-2-[[(RS)-(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethylpyridine 1-oxide (as per EP). It is also known as Omeprazole USP Related Compound E. Omeprazole EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Omeprazole EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Omeprazole.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Related products

Omeprazole Sodium

SZ CAT No:	: SZ-O004001
CAS No	: 95510-70-6
Mol.F.	: C17H19N3O3S : Na
Mol.Wt.	: 345.4 : 23.0
Inv. Status	: In Stock
Rel. CAS No	: 73590-58-6 (free base)

Omeprazole EP Impurity A

SZ CAT No:	: SZ-O004002
CAS No	: 37052-78-1
Mol.F.	: C8H8N2OS
Mol.Wt.	: 180.2
Inv. Status	: In Stock
Rel. CAT No	: SZ-E001002 ,

Omeprazole EP Impurity B

SZ CAT No:	: SZ-O004003
CAS No	: 110374-16-8
Mol.F.	: C16H17N3O2S
Mol.Wt.	: 315.4
Inv. Status	: In Stock

Omeprazole EP Impurity C

SZ CAT No:	: SZ-O004004
CAS No	: 73590-85-9
Mol.F.	: C17H19N3O2S
Mol.Wt.	: 329.4
Inv. Status	: In Stock
Rel. CAS No	: 220757-75-5 (HCl salt)

Omeprazole EP Impurity D

SZ CAT No:	: SZ-O004005
CAS No	: 88546-55-8
Mol.F.	: C17H19N3O4S
Mol.Wt.	: 361.4
Inv. Status	: In Stock

Omeprazole EP Impurity E

SZ CAT No:	: SZ-O004006
CAS No	: 176219-04-8
Mol.F.	: C17H19N3O4S
Mol.Wt.	: 361.4
Inv. Status	: In Stock

Omeprazole EP Impurity F

SZ CAT No:	: SZ-O004007
CAS No	: 125656-82-8
Mol.F.	: C16H13N3O2S
Mol.Wt.	: 311.4
Inv. Status	: In Stock

Omeprazole EP Impurity G

SZ CAT No:	: SZ-O004008
CAS No	: 125656-83-9
Mol.F.	: C16H13N3O2S
Mol.Wt.	: 311.4
Inv. Status	: In Stock

Omeprazole EP Impurity H

SZ CAT No:	: SZ-O004009
CAS No	: 863029-89-4
Mol.F.	: C16H16ClN3O2S
Mol.Wt.	: 349.8
Inv. Status	: In Stock

Omeprazole EP Impurity I

SZ CAT No:	: SZ-O004010
CAS No	: 158812-85-2
Mol.F.	: C17H19N3O5S
Mol.Wt.	: 377.4
Inv. Status	: In Stock

Omeprazole EP Impurity XI

SZ CAT No:	: SZ-O004011
CAS No	: 86604-75-3
Mol.F.	: C9H12ClNO : HCl
Mol.Wt.	: 185.7 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 84006-10-0 (free base)

Omeprazole N-Methyl 5-Methoxy Analog

SZ CAT No:	: SZ-O004012
CAS No	: 89352-76-1
Mol.F.	: C18H21N3O3S
Mol.Wt.	: 359.4
Inv. Status	: In Stock

Omeprazole N-Methyl 6-Methoxy Analog

SZ CAT No:	: SZ-O004013
CAS No	: 784143-42-6
Mol.F.	: C18H21N3O3S
Mol.Wt.	: 359.4
Inv. Status	: In Stock

Omeprazole Pyridone Acid Sodium Salt

SZ CAT No:	: SZ-O004014
CAS No	: NA
Mol.F.	: C16H14N3O4 : Na
Mol.Wt.	: 312.3 : 23.0
Inv. Status	: In Stock
Rel. CAS No	: 1227380-90-6 (Free base)

Omeprazole 4-Desmethyl Impurity

SZ CAT No:	: SZ-O004016
CAS No	: 301669-82-9
Mol.F.	: C16H17N3O3S
Mol.Wt.	: 331.4
Inv. Status	: Custom Synthesis

Omeprazole N1-Methyl 5-Methoxy Thiol Impurity

SZ CAT No:	: SZ-O004017
CAS No	: NA
Mol.F.	: C9H10N2OS
Mol.Wt.	: 194.3
Inv. Status	: Custom Synthesis

Omeprazole N1-Methyl 6-Methoxy Thiol Impurity

SZ CAT No:	: SZ-O004018
CAS No	: NA
Mol.F.	: C9H10N2OS
Mol.Wt.	: 194.3
Inv. Status	: Custom Synthesis

Omeprazole Sulfide N1-Methyl 5-Methoxy Analog

SZ CAT No:	: SZ-O004019
CAS No	: 2243644-60-0
Mol.F.	: C18H21N3O2S
Mol.Wt.	: 343.4
Inv. Status	: Custom Synthesis

Omeprazole S-Isomer

SZ CAT No:	: SZ-O004020
CAS No	: 119141-88-7
Mol.F.	: C17H19N3O3S
Mol.Wt.	: 345.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 2

SZ CAT No:	: SZ-O004021
CAS No	: 583-39-1
Mol.F.	: C7H6N2S
Mol.Wt.	: 150.2
Inv. Status	: In Stock

Omeprazole Impurity 3

SZ CAT No:	: SZ-O004022
CAS No	: NA
Mol.F.	: C16H17N3O2
Mol.Wt.	: 283.3
Inv. Status	: In Stock

Omeprazole EP Impurity F and G mixture

SZ CAT No:	: SZ-O004023
CAS No	: NA
Mol.F.	: C16H13N3O2S
Mol.Wt.	: 311.4
Inv. Status	: In Stock

Omeprazole

SZ CAT No:	: SZ-O004024
CAS No	: 73590-58-6
Mol.F.	: C17H19N3O3S
Mol.Wt.	: 345.4
Inv. Status	: In Stock

Mixture of N-Methyl 5-Methoxy & N-Methyl 6-Methoxy Analog

SZ CAT No:	: SZ-O004025
CAS No	: N/A
Mol.F.	: C18H21N3O3S
Mol.Wt.	: 359.4
Inv. Status	: In Stock

(R) Omeprazole Potassium Salt

SZ CAT No:	: SZ-O004026
CAS No	: 161796-81-2
Mol.F.	: C17H19N3O3S : K
Mol.Wt.	: 345.4 : 39.1
Inv. Status	: In Stock
Rel. CAS No	: 119141-89-8 (free base)

(R) Omeprazole Sodium Salt

SZ CAT No:	: SZ-O004027
CAS No	: 161796-77-6
Mol.F.	: C17H19N3O3S : Na
Mol.Wt.	: 345.4 : 23.0
Inv. Status	: In Stock
Rel. CAS No	: 119141-89-8 (free base)

Omeprazole D3

SZ CAT No:	: SZ-O004D01
CAS No	: 934293-92-2
Mol.F.	: C17H16D3N3O3S
Mol.Wt.	: 348.4
Inv. Status	: Custom Synthesis

Omeprazole sulfone D3

SZ CAT No:	: SZ-O004D02
CAS No	: 1189891-71-1
Mol.F.	: C17H16D3N3O4S
Mol.Wt.	: 364.4
Inv. Status	: Custom Synthesis

5-Hydroxy Omeprazole D3

SZ CAT No:	: SZ-O004D03
CAS No	: 1189882-58-3
Mol.F.	: C17H16D3N3O4S
Mol.Wt.	: 364.4
Inv. Status	: Custom Synthesis

Omeprazole Hydroxymethyl Impurity

SZ CAT No:	: SZ-O004028
CAS No	: 96300-88-8
Mol.F.	: C9H13NO2 . HCl
Mol.Wt.	: 167.2 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 86604-78-6 (free base)

4-Desmethoxy Omeprazole Sulfide

SZ CAT No:	: SZ-O004030
CAS No	: 704910-89-4
Mol.F.	: C16H17N3OS
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 5

SZ CAT No:	: SZ-O004031
CAS No	: 73590-87-1
Mol.F.	: C16H17N3OS
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

Bis-Desmethoxy Omeprazole Sulfide

SZ CAT No:	: SZ-O004032
CAS No	: 704910-94-1
Mol.F.	: C15H15N3S
Mol.Wt.	: 269.4
Inv. Status	: Custom Synthesis

4-Desmethoxy-4-chloro Omeprazole Sulfide

SZ CAT No:	: SZ-O004033
CAS No	: 220757-74-4
Mol.F.	: C16H16ClN3OS
Mol.Wt.	: 333.8
Inv. Status	: In Stock
Rel. CAS No	: 1250376-48-7 (HCl salt)

Omeprazole Dimer Impurity

SZ CAT No:	: SZ-O004034
CAS No	: NA
Mol.F.	: C26H27N5O4S2
Mol.Wt.	: 537.7
Inv. Status	: Custom Synthesis

Desulfoxide 4-Demethyl Omeprazole

SZ CAT No:	: SZ-O004035
CAS No	: 1384163-92-1
Mol.F.	: C16H17N3O2
Mol.Wt.	: 283.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 1

SZ CAT No:	: SZ-O004036
CAS No	: 151602-50-5
Mol.F.	: C16H17N3O2S
Mol.Wt.	: 315.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 6

SZ CAT No:	: SZ-O004037
CAS No	: NA
Mol.F.	: C8H10ClNO
Mol.Wt.	: 171.6
Inv. Status	: Custom Synthesis

Omeprazole Impurity 7

SZ CAT No:	: SZ-O004038
CAS No	: 1346649-67-9
Mol.F.	: C16H15N3O2S
Mol.Wt.	: 313.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 8

SZ CAT No:	: SZ-O004039
CAS No	: NA
Mol.F.	: C17H19N3O3S
Mol.Wt.	: 345.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 9

SZ CAT No:	: SZ-O004040
CAS No	: NA
Mol.F.	: C16H15N3O3
Mol.Wt.	: 297.3
Inv. Status	: Custom Synthesis

N-Nitroso Omeprazol

SZ CAT No:	: SZ-O004041
CAS No	: NA
Mol.F.	: C17H18N4O4S
Mol.Wt.	: 374.4
Inv. Status	: Inquire

Omeprazole Impurity 10

SZ CAT No:	: SZ-O004042
CAS No	: 14248-66-9
Mol.F.	: C7H8N2O3
Mol.Wt.	: 168.2
Inv. Status	: Custom Synthesis

Omeprazole Impurity 11

SZ CAT No:	: SZ-O004043
CAS No	: NA
Mol.F.	: C16H19N3O2
Mol.Wt.	: 285.3
Inv. Status	: Custom Synthesis

Omeprazole Magnesium

SZ CAT No:	: SZ-O004044
CAS No	: 95382-33-5
Mol.F.	: 2(C17H18N3O3S) : Mg
Mol.Wt.	: 2(344.4) : 24.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 12

SZ CAT No:	: SZ-O004045
CAS No	: NA
Mol.F.	: C17H17N3O4S
Mol.Wt.	: 359.4
Inv. Status	: Custom Synthesis

Omeprazole-13C,D3

SZ CAT No:	: SZ-O004D04
CAS No	: 1261395-28-1
Mol.F.	: C1613CH16D3N3O3S
Mol.Wt.	: 349.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 14

SZ CAT No:	: SZ-O004048
CAS No	: NA
Mol.F.	: C15H13N3O4
Mol.Wt.	: 299.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 15

SZ CAT No:	: SZ-O004049
CAS No	: 149367-83-9
Mol.F.	: C8H8N2OS
Mol.Wt.	: 180.2
Inv. Status	: Custom Synthesis

4'-Desmethoxy Omeprazole

SZ CAT No:	: SZ-O004050
CAS No	: 73590-60-0
Mol.F.	: C16H17N3O2S
Mol.Wt.	: 315.4
Inv. Status	: In Stock

Des-Methoxy Esomeprazole

SZ CAT No:	: SZ-O004051
CAS No	: 704910-88-3
Mol.F.	: C15H15N3OS
Mol.Wt.	: 285.4
Inv. Status	: Custom Synthesis

5-Hydroxy Omeprazole

SZ CAT No:	: SZ-O004052
CAS No	: 92340-57-3
Mol.F.	: C17H19N3O4S
Mol.Wt.	: 361.4
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1215629-45-0 (sodium salt)

Omeprazole Impurity 16

SZ CAT No:	: SZ-O004053
CAS No	: 106135-28-8
Mol.F.	: C8H8N2O4S
Mol.Wt.	: 228.2
Inv. Status	: Custom Synthesis

Omeprazole Impurity 17

SZ CAT No:	: SZ-O004054
CAS No	: NA
Mol.F.	: C17H21N3O2
Mol.Wt.	: 299.4
Inv. Status	: Custom Synthesis

Omeprazole Acid Methyl Ester

SZ CAT No:	: SZ-O004055
CAS No	: 120003-83-0
Mol.F.	: C18H19N3O5S
Mol.Wt.	: 389.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 18

SZ CAT No:	: SZ-O004056
CAS No	: 121459-89-0
Mol.F.	: C17H18N3O2S+ : Cl
Mol.Wt.	: 328.4 : 35.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 102283-05-6 (free base)

5-Benzyloxy Omeprazole

SZ CAT No:	: SZ-O004057
CAS No	: 1215799-39-5
Mol.F.	: C23H23N3O3S
Mol.Wt.	: 421.5
Inv. Status	: Custom Synthesis

5-O-Desmethyl Omeprazole Sulfide

SZ CAT No:	: SZ-O004058
CAS No	: 103877-02-7
Mol.F.	: C16H17N3O2S
Mol.Wt.	: 315.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 19

SZ CAT No:	: SZ-O004059
CAS No	: 86604-80-0
Mol.F.	: C9H13NO2
Mol.Wt.	: 167.2
Inv. Status	: Custom Synthesis

Omeprazole Impurity 20

SZ CAT No:	: SZ-O004060
CAS No	: 220771-03-9
Mol.F.	: C8H10ClNO
Mol.Wt.	: 171.6
Inv. Status	: In Stock
Rel. CAS No	: 220770-99-0 (HCl salt)

Omeprazole Impurity 21

SZ CAT No:	: SZ-O004061
CAS No	: 447461-23-6
Mol.F.	: C8H11NO
Mol.Wt.	: 137.2
Inv. Status	: Custom Synthesis

Omeprazole Impurity 22

SZ CAT No:	: SZ-O004062
CAS No	: 86604-74-2
Mol.F.	: C8H10ClNO : HCl
Mol.Wt.	: 171.6 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 124473-12-7 (free base)

Omeprazole Impurity 23

SZ CAT No:	: SZ-O004063
CAS No	: NA
Mol.F.	: C17H19N3O2
Mol.Wt.	: 297.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 24

SZ CAT No:	: SZ-O004064
CAS No	: 2451927-87-8
Mol.F.	: C17H17N3O2S
Mol.Wt.	: 327.4
Inv. Status	: Custom Synthesis

Omeprazole Impurity 25

SZ CAT No:	: SZ-O004065
CAS No	: 2451927-89-0
Mol.F.	: C17H17N3O3
Mol.Wt.	: 311.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 26

SZ CAT No:	: SZ-O004066
CAS No	: 2451927-94-7
Mol.F.	: C16H17N3O2
Mol.Wt.	: 283.3
Inv. Status	: In Stock

Omeprazole Impurity 27

SZ CAT No:	: SZ-O004067
CAS No	: 2451927-95-8
Mol.F.	: C16H17N3O3
Mol.Wt.	: 299.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 28

SZ CAT No:	: SZ-O004068
CAS No	: 102-51-2
Mol.F.	: C7H10N2O
Mol.Wt.	: 138.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 59548-39-9 (2HCl salt) ; 106658-14-4 (HCl salt)

Omeprazole Impurity 29

SZ CAT No:	: SZ-O004069
CAS No	: 20033-99-2
Mol.F.	: C9H10N2O2
Mol.Wt.	: 178.2
Inv. Status	: Custom Synthesis

Omeprazole Impurity 30

SZ CAT No:	: SZ-O004070
CAS No	: 1346600-29-0
Mol.F.	: C26H30N4O3S
Mol.Wt.	: 478.6
Inv. Status	: Custom Synthesis

Omeprazole Impurity 32

SZ CAT No:	: SZ-O004072
CAS No	: NA
Mol.F.	: C17H17N3O4
Mol.Wt.	: 327.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 33

SZ CAT No:	: SZ-O004073
CAS No	: NA
Mol.F.	: C17H17N3O4
Mol.Wt.	: 327.3
Inv. Status	: Custom Synthesis

Omeprazole Impurity 34

SZ CAT No:	: SZ-O004074
CAS No	: NA
Mol.F.	: C17H17N3O2S
Mol.Wt.	: 327.4
Inv. Status	: Custom Synthesis

Omeprazole EP Impurity E

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