Nintedanib

SZ CAT No:	SZ-N023001
CAS No	656247-17-5
Mol.F.	C31H33N5O4
Mol.Wt.	539.6
Inv. Status	In Stock
Rel. CAS No	656247-18-6 (Esylate salt)
Shipping Condition	Ambient Temperature

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Chemical Name: (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester ; Intedanib ; Vargatef

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1/C(C2=CC=C(C(OC)=O)C=C2N1)=C(C3=CC=CC=C3)\NC4=CC=C(N(C)C(CN5CCN(C)CC5)=O)C=C4

Nintedanib is chemically (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-H-Indole-6-carboxylic Acid Methyl Ester ; Intedanib ; Vargatef. Nintedanib is supplied with detailed characterization data compliant with regulatory guideline. Nintedanib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nintedanib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Nintedanib

SZ CAT No:	: SZ-N023001
CAS No	: 656247-17-5
Mol.F.	: C31H33N5O4
Mol.Wt.	: 539.6
Inv. Status	: In Stock
Rel. CAS No	: 656247-18-6 (Esylate salt)

Nintedanib Esylate

SZ CAT No:	: SZ-N023002
CAS No	: 656247-18-6
Mol.F.	: C31H33N5O4 : C2H6O3S
Mol.Wt.	: 539.6 : 110.1
Inv. Status	: In Stock
Rel. CAS No	: 656247-17-5 (free base)

Nintedanib E-Isomer

SZ CAT No:	: SZ-N023003
CAS No	: NA
Mol.F.	: C31H33N5O4
Mol.Wt.	: 539.6
Inv. Status	: Custom Synthesis

Nintedanib Impurity A

SZ CAT No:	: SZ-N023004
CAS No	: NA
Mol.F.	: C29H29N5O4
Mol.Wt.	: 511.6
Inv. Status	: Out of Stock

Nintedanib Impurity C

SZ CAT No:	: SZ-N023006
CAS No	: NA
Mol.F.	: C30H31N5O4
Mol.Wt.	: 525.6
Inv. Status	: In Stock

Nintedanib N-Methyl Aniline Analog

SZ CAT No:	: SZ-N023007
CAS No	: 1987887-92-2
Mol.F.	: C24H21N3O3
Mol.Wt.	: 399.5
Inv. Status	: In Stock

Nintedanib Impurity E

SZ CAT No:	: SZ-N023008
CAS No	: 1610881-60-1
Mol.F.	: C29H31N5O2
Mol.Wt.	: 481.6
Inv. Status	: In Stock

Nintedanib Impurity F

SZ CAT No:	: SZ-N023009
CAS No	: NA
Mol.F.	: C44H51N9O4
Mol.Wt.	: 770
Inv. Status	: Custom Synthesis

Nintedanib N,N-Dioxide

SZ CAT No:	: SZ-N023011
CAS No	: 2734676-68-5
Mol.F.	: C31H33N5O6
Mol.Wt.	: 571.6
Inv. Status	: In Stock

Nintedanib Impurity 1

SZ CAT No:	: SZ-N023012
CAS No	: 2514952-69-1
Mol.F.	: C12H11NO5
Mol.Wt.	: 249.2
Inv. Status	: Custom Synthesis

Nintedanib Impurity 2

SZ CAT No:	: SZ-N023013
CAS No	: 1174335-83-1
Mol.F.	: C20H16ClNO5
Mol.Wt.	: 385.8
Inv. Status	: In Stock

Nintedanib Impurity 3

SZ CAT No:	: SZ-N023014
CAS No	: 1168150-46-6
Mol.F.	: C18H15NO4
Mol.Wt.	: 309.3
Inv. Status	: In Stock

Nintedanib Carboxylic Acid

SZ CAT No:	: SZ-N023017
CAS No	: 894783-71-2
Mol.F.	: C30H31N5O4
Mol.Wt.	: 525.6
Inv. Status	: In Stock

Nintedanib Impurity 7

SZ CAT No:	: SZ-N023018
CAS No	: NA
Mol.F.	: C19H14ClNO5
Mol.Wt.	: 371.8
Inv. Status	: Custom Synthesis

Nintedanib Impurity 8

SZ CAT No:	: SZ-N023019
CAS No	: 2093243-16-2
Mol.F.	: C17H13NO4
Mol.Wt.	: 295.3
Inv. Status	: In Stock

Nintedanib N-Oxide Impurity 1

SZ CAT No:	: SZ-N023021
CAS No	: NA
Mol.F.	: C31H33N5O5
Mol.Wt.	: 555.6
Inv. Status	: Limited Stock

Nintedanib N-Oxide Impurity 2

SZ CAT No:	: SZ-N023022
CAS No	: 2734666-06-7
Mol.F.	: C31H33N5O5
Mol.Wt.	: 555.6
Inv. Status	: In Stock

Nintedanib Impurity 12

SZ CAT No:	: SZ-N023023
CAS No	: NA
Mol.F.	: C34H37N5O6
Mol.Wt.	: 611.7
Inv. Status	: Custom Synthesis

Nintedanib Impurity 13

SZ CAT No:	: SZ-N023024
CAS No	: NA
Mol.F.	: C36H41N5O6
Mol.Wt.	: 639.8
Inv. Status	: Custom Synthesis

Nintedanib Impurity 15

SZ CAT No:	: SZ-N023026
CAS No	: 1027407-75-5
Mol.F.	: C21H19NO5
Mol.Wt.	: 365.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 16

SZ CAT No:	: SZ-N023027
CAS No	: NA
Mol.F.	: C21H19NO6
Mol.Wt.	: 381.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 17

SZ CAT No:	: SZ-N023028
CAS No	: NA
Mol.F.	: C16H26N4O
Mol.Wt.	: 290.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 18

SZ CAT No:	: SZ-N023029
CAS No	: 2936656-87-8
Mol.F.	: C15H24N4O
Mol.Wt.	: 276.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 19

SZ CAT No:	: SZ-N023030
CAS No	: 2095628-55-8
Mol.F.	: C20H19NO4
Mol.Wt.	: 337.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 20

SZ CAT No:	: SZ-N023031
CAS No	: 1912-28-3
Mol.F.	: C3H8O3S
Mol.Wt.	: 124.2
Inv. Status	: In Stock

Nintedanib Impurity 22

SZ CAT No:	: SZ-N023033
CAS No	: 2410284-89-6
Mol.F.	: C22H30N6O2
Mol.Wt.	: 410.5
Inv. Status	: In Stock

Nintedanib N-Glucuronide-1

SZ CAT No:	: SZ-N023034
CAS No	: NA
Mol.F.	: C37H41N5O10
Mol.Wt.	: 715.8
Inv. Status	: Custom Synthesis

Nintedanib N-Glucuronide-2

SZ CAT No:	: SZ-N023035
CAS No	: NA
Mol.F.	: C37H41N5O10
Mol.Wt.	: 715.8
Inv. Status	: Custom Synthesis

Nintedanib Impurity 23

SZ CAT No:	: SZ-N023036
CAS No	: NA
Mol.F.	: C32H35N5O4
Mol.Wt.	: 553.7
Inv. Status	: In Stock

Nintedanib Ethyl Ester

SZ CAT No:	: SZ-N023037
CAS No	: 1139455-52-9
Mol.F.	: C32H35N5O4
Mol.Wt.	: 553.7
Inv. Status	: In Stock

Nintedanib Methyl Impurity

SZ CAT No:	: SZ-N023038
CAS No	: 2734410-06-9
Mol.F.	: C32H35N5O4
Mol.Wt.	: 553.7
Inv. Status	: Custom Synthesis

Nintedanib Acetyl Impurity

SZ CAT No:	: SZ-N023039
CAS No	: 1139458-48-2
Mol.F.	: C26H23N3O4
Mol.Wt.	: 441.5
Inv. Status	: In Stock

Nintedanib 4-Hydroxyphenyl Analog

SZ CAT No:	: SZ-N023041
CAS No	: 2519501-85-8
Mol.F.	: C23H18N2O4
Mol.Wt.	: 386.4
Inv. Status	: In Stock

Nintedanib N-Acetyl Impurity

SZ CAT No:	: SZ-N023042
CAS No	: 2380229-45-6
Mol.F.	: C33H35N5O5
Mol.Wt.	: 581.7
Inv. Status	: In Stock

Nintedanib Impurity 27

SZ CAT No:	: SZ-N023043
CAS No	: 150784-50-2
Mol.F.	: C13H19N3O
Mol.Wt.	: 233.3
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1837959-34-8 (HCl salt)

Nintedanib Impurity 28

SZ CAT No:	: SZ-N023044
CAS No	: 2410649-54-4
Mol.F.	: C22H26N6O6
Mol.Wt.	: 470.5
Inv. Status	: In Stock

Nintedanib Impurity 29

SZ CAT No:	: SZ-N023045
CAS No	: 2117628-65-4
Mol.F.	: C14H22N4O
Mol.Wt.	: 262.4
Inv. Status	: Custom Synthesis

Nintedanib Impurity 30

SZ CAT No:	: SZ-N023046
CAS No	: 652140-02-8
Mol.F.	: C18H28N4O3
Mol.Wt.	: 348.4
Inv. Status	: Custom Synthesis

Nintedanib Acetamide Impurity

SZ CAT No:	: SZ-N023047
CAS No	: 262368-25-2
Mol.F.	: C13H20N4O
Mol.Wt.	: 248.3
Inv. Status	: Custom Synthesis

Nintedanib Impurity 31

SZ CAT No:	: SZ-N023048
CAS No	: 1799894-54-4
Mol.F.	: C32H36N5O4
Mol.Wt.	: 554.7
Inv. Status	: Custom Synthesis

Nintedanib Dimer

SZ CAT No:	: SZ-N023050
CAS No	: 2410284-90-9
Mol.F.	: C56H52N8O8
Mol.Wt.	: 965.1
Inv. Status	: In Stock

Despiperazinyl Nintedanib E-Isomer

SZ CAT No:	: SZ-N023052
CAS No	: NA
Mol.F.	: C25H23N3O3
Mol.Wt.	: 413.5
Inv. Status	: Custom Synthesis

Nintedanib Impurity 32

SZ CAT No:	: SZ-N023049
CAS No	: 262368-30-9
Mol.F.	: C14H22N4O
Mol.Wt.	: 262.4
Inv. Status	: In Stock

Nintedanib Impurity 34

SZ CAT No:	: SZ-N023051
CAS No	: 1235004-99-5
Mol.F.	: C10H7NO3
Mol.Wt.	: 189.2
Inv. Status	: Custom Synthesis

Nintedanib N-Acyl Methoxyenolindole

SZ CAT No:	: SZ-N023053
CAS No	: 1168152-07-5
Mol.F.	: C20H17NO5
Mol.Wt.	: 351.4
Inv. Status	: In Stock

Nintedanib Impurity 37

SZ CAT No:	: SZ-N023055
CAS No	: 2653-16-9
Mol.F.	: C9H9ClN2O3
Mol.Wt.	: 228.6
Inv. Status	: In Stock

Nintedanib Impurity 38

SZ CAT No:	: SZ-N023056
CAS No	: 1160293-27-5
Mol.F.	: C13H13NO8
Mol.Wt.	: 311.2
Inv. Status	: In Stock

Nintedanib 13C D3

SZ CAT No:	: SZ-N023D01
CAS No	: NA
Mol.F.	: C3013CH30D3N5O4
Mol.Wt.	: 543.6
Inv. Status	: Custom Synthesis
Rel. CAS No	: 656247-17-5 (unlabelled)

Nintedanib Ethoxy Enolindole

SZ CAT No:	: SZ-N023010
CAS No	: 656247-19-7
Mol.F.	: C19H17NO4
Mol.Wt.	: 323.3
Inv. Status	: Custom Synthesis

N-Nitroso Nintedanib

SZ CAT No:	: SZ-N023016
CAS No	: NA
Mol.F.	: C31H32N6O5
Mol.Wt.	: 568.6
Inv. Status	: Inquire

Nintedanib Impurity 39

SZ CAT No:	: SZ-N023057
CAS No	: NA
Mol.F.	: C26H31N5O4
Mol.Wt.	: 477.6
Inv. Status	: Custom Synthesis

N-Nitroso Nintedanib Impurity 1

SZ CAT No:	: SZ-N023020
CAS No	: NA
Mol.F.	: C31H32N6O5
Mol.Wt.	: 568.6
Inv. Status	: Inquire

N-Nitroso-N-Desmethylnintedanib

SZ CAT No:	: SZ-N023040
CAS No	: NA
Mol.F.	: C30H30N6O5
Mol.Wt.	: 554.6
Inv. Status	: In Stock

Nintedanib Impurity 42

SZ CAT No:	: SZ-N023060
CAS No	: NA
Mol.F.	: C32H32N6O4
Mol.Wt.	: 564.6
Inv. Status	: Custom Synthesis

Nintedanib Impurity 43

SZ CAT No:	: SZ-N023061
CAS No	: 856844-57-0
Mol.F.	: C20H26N6O2
Mol.Wt.	: 382.5
Inv. Status	: Custom Synthesis

Nintedanib Impurity 44

SZ CAT No:	: SZ-N023062
CAS No	: 2765161-53-1
Mol.F.	: C13H15NO6
Mol.Wt.	: 281.3
Inv. Status	: Custom Synthesis

Nintedanib Impurity 45

SZ CAT No:	: SZ-N023063
CAS No	: 954239-49-7
Mol.F.	: C11H11NO3
Mol.Wt.	: 205.2
Inv. Status	: Custom Synthesis

6-Carboxyoxindole

SZ CAT No:	: SZ-N023064
CAS No	: 334952-09-9
Mol.F.	: C9H7NO3
Mol.Wt.	: 177.2
Inv. Status	: Custom Synthesis

Nintedanib Impurity 46

SZ CAT No:	: SZ-N023065
CAS No	: NA
Mol.F.	: C32H32N6O4
Mol.Wt.	: 564.6
Inv. Status	: Custom Synthesis

Nintedanib Impurity 47

SZ CAT No:	: SZ-N023066
CAS No	: NA
Mol.F.	: C16H13NO4
Mol.Wt.	: 283.3
Inv. Status	: Custom Synthesis

Nintedanib Impurity 48

SZ CAT No:	: SZ-N023067
CAS No	: 1803562-96-0
Mol.F.	: C11H13NO4
Mol.Wt.	: 223.2
Inv. Status	: Custom Synthesis

Nintedanib

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