Nicardipine Dehydro Carboxylic Acid Impurity

SZ CAT No:	SZ-N004010
CAS No	64603-72-1
Mol.F.	C16H14N2O6
Mol.Wt.	330.3
Inv. Status	In Stock

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Chemical Name: 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinic acid

Synonym: Nicardipine Pyridine Monoacid Impurity

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(O)C1=C(C)N=C(C)C(C(OC)=O)=C1C2=CC=CC([N+]([O-])=O)=C2

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181

Nicardipine Dehydro Carboxylic Acid Impurity is chemically 5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)nicotinic acid. It is also known as Nicardipine Pyridine Monoacid Impurity. Nicardipine Dehydro Carboxylic Acid Impurity is supplied with detailed characterization data compliant with regulatory guideline. Nicardipine Dehydro Carboxylic Acid Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nicardipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

SZ CAT No:	: SZ-N004001
CAS No	: 54527-84-3
Mol.F.	: C26H29N3O6 : HCl
Mol.Wt.	: 479.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 55985-32-5 (free base)

SZ CAT No:	: SZ-N004003
CAS No	: 1216817-27-4
Mol.F.	: C26H27N3O6 : HCl
Mol.Wt.	: 477.5 : 36.5
Inv. Status	: In Stock
Rel. CAS No	: 59875-58-0 (free base) ; 2771193-14-5 (Oxalate salt)

SZ CAT No:	: SZ-N004005
CAS No	: 499-81-0
Mol.F.	: C7H5NO4
Mol.Wt.	: 167.1
Inv. Status	: In Stock
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SZ CAT No:	: SZ-N004007
CAS No	: 40055-37-6
Mol.F.	: C8H8N2O
Mol.Wt.	: 148.2
Inv. Status	: In Stock
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SZ CAT No:	: SZ-N004008
CAS No	: 71784-27-5
Mol.F.	: C35H40N4O6 : 2(HCl)
Mol.Wt.	: 612.7 : 2(36.5)
Inv. Status	: In Stock
Rel. CAS No	: 71791-90-7 (free base)

Nicardipine Dehydro Carboxylic Acid Impurity

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SZ CAT No:	: SZ-N004002
CAS No	: 74936-72-4
Mol.F.	: C16H16N2O6
Mol.Wt.	: 332.3
Inv. Status	: In Stock

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CAS No	: 21881-77-6
Mol.F.	: C17H18N2O6
Mol.Wt.	: 346.3
Inv. Status	: In Stock

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Mol.F.	: C15H15NO5
Mol.Wt.	: 289.3
Inv. Status	: In Stock

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CAS No	: 76258-20-3
Mol.F.	: C17H16N2O6
Mol.Wt.	: 344.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004010
CAS No	: 64603-72-1
Mol.F.	: C16H14N2O6
Mol.Wt.	: 330.3
Inv. Status	: In Stock

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Mol.F.	: C13H13NO3
Mol.Wt.	: 231.3
Inv. Status	: In Stock

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CAS No	: 2469735-68-8
Mol.F.	: C15H15NO5
Mol.Wt.	: 289.3
Inv. Status	: Custom Synthesis

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Mol.F.	: C26H26D3N3O6 : HCl
Mol.Wt.	: 482.6 : 36.5
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1189945-63-8 (free base)

SZ CAT No:	: SZ-N004013
CAS No	: NA
Mol.F.	: C15H17NO6
Mol.Wt.	: 307.3
Inv. Status	: In Stock

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CAS No	: 206976-29-6
Mol.F.	: C17H18N2O5
Mol.Wt.	: 330.3
Inv. Status	: Custom Synthesis

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CAS No	: NA
Mol.F.	: C26H28N4O7
Mol.Wt.	: 508.5
Inv. Status	: Inquire

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CAS No	: 101-98-4
Mol.F.	: C10H15NO
Mol.Wt.	: 165.2
Inv. Status	: Custom Synthesis
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Mol.F.	: C19H23N3O6
Mol.Wt.	: 389.4
Inv. Status	: In Stock
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CAS No	: 123973-71-7
Mol.F.	: C25H27N3O6
Mol.Wt.	: 465.5
Inv. Status	: Custom Synthesis
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CAS No	: NA
Mol.F.	: C26H28N2O7
Mol.Wt.	: 480.5
Inv. Status	: Custom Synthesis

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Mol.F.	: C18H18N2O6
Mol.Wt.	: 358.4
Inv. Status	: Custom Synthesis
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Mol.F.	: C26H29N3O7
Mol.Wt.	: 495.5
Inv. Status	: In Stock

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CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

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CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

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CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

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CAS No	: NA
Mol.F.	: C19H22N4O7
Mol.Wt.	: 418.4
Inv. Status	: Custom Synthesis

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CAS No	: NA
Mol.F.	: C26H32N4O7
Mol.Wt.	: 512.6
Inv. Status	: Custom Synthesis

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CAS No	: 2771193-14-5
Mol.F.	: C26H27N3O6 : C2H2O4
Mol.Wt.	: 477.5 : 90.0
Inv. Status	: In Stock
Rel. CAS No	: 59875-58-0 (free base) ; 1216817-27-4 (HCl salt)

SZ CAT No:	: SZ-N004030
CAS No	: NA
Mol.F.	: C25H26N4O7
Mol.Wt.	: 494.5
Inv. Status	: Custom Synthesis