Nicardipine Hydrochloride

SZ CAT No:	SZ-N004001
CAS No	54527-84-3
Mol.F.	C26H29N3O6 : HCl
Mol.Wt.	479.5 : 36.5
Inv. Status	In Stock
Rel. CAS No	55985-32-5 (free base)
Shipping Condition	Ambient Temperature

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Chemical Name: 3-[2-[Benzyl(methyl)amino]ethyl] 5-methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride (as per EP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=C(C)NC(C)=C(C(OCCN(CC2=CC=CC=C2)C)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OC.Cl

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-Olayan
Arabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain
Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández D. F. Mira G. I. Luque
Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

Identification and characterization of a novel potential degradant and development and validation of stability-indicating rp-lc method for nicardipine impurities in injectable dosage form
Bhupendrasinh K. Vaghela &Surendra Singh Rao
Journal of Liquid Chromatography & Related Technologies Volume 36, 2013 - Issue 15 Pages 2166-2181

Nicardipine Hydrochloride is chemically 3-[2-[Benzyl(methyl)amino]ethyl] 5-methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride (as per EP). Nicardipine Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Nicardipine Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nicardipine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Nicardipine Hydrochloride

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SZ CAT No:	: SZ-N004001
CAS No	: 54527-84-3
Mol.F.	: C26H29N3O6 : HCl
Mol.Wt.	: 479.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004002
CAS No	: 74936-72-4
Mol.F.	: C16H16N2O6
Mol.Wt.	: 332.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004003
CAS No	: 1216817-27-4
Mol.F.	: C26H27N3O6 : HCl
Mol.Wt.	: 477.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004004
CAS No	: 21881-77-6
Mol.F.	: C17H18N2O6
Mol.Wt.	: 346.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004005
CAS No	: 499-81-0
Mol.F.	: C7H5NO4
Mol.Wt.	: 167.1
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004006
CAS No	: 87625-92-1
Mol.F.	: C15H15NO5
Mol.Wt.	: 289.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004007
CAS No	: 40055-37-6
Mol.F.	: C8H8N2O
Mol.Wt.	: 148.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004008
CAS No	: 71784-27-5
Mol.F.	: C35H40N4O6 : 2(HCl)
Mol.Wt.	: 612.7 : 2(36.5)
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004009
CAS No	: 76258-20-3
Mol.F.	: C17H16N2O6
Mol.Wt.	: 344.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004010
CAS No	: 64603-72-1
Mol.F.	: C16H14N2O6
Mol.Wt.	: 330.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004011
CAS No	: 10323-98-5
Mol.F.	: C13H13NO3
Mol.Wt.	: 231.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004012
CAS No	: 2469735-68-8
Mol.F.	: C15H15NO5
Mol.Wt.	: 289.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004D01
CAS No	: 1432061-50-1
Mol.F.	: C26H26D3N3O6 : HCl
Mol.Wt.	: 482.6 : 36.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004013
CAS No	: NA
Mol.F.	: C15H17NO6
Mol.Wt.	: 307.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004015
CAS No	: 206976-29-6
Mol.F.	: C17H18N2O5
Mol.Wt.	: 330.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004016
CAS No	: NA
Mol.F.	: C26H28N4O7
Mol.Wt.	: 508.5
Inv. Status	: Inquire

SZ CAT No:	: SZ-N004017
CAS No	: 101-98-4
Mol.F.	: C10H15NO
Mol.Wt.	: 165.2
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004018
CAS No	: 58368-87-9
Mol.F.	: C19H23N3O6
Mol.Wt.	: 389.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004019
CAS No	: 123973-71-7
Mol.F.	: C25H27N3O6
Mol.Wt.	: 465.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004020
CAS No	: NA
Mol.F.	: C26H28N2O7
Mol.Wt.	: 480.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004022
CAS No	: 89267-41-4
Mol.F.	: C18H18N2O6
Mol.Wt.	: 358.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004023
CAS No	: 2724510-66-9
Mol.F.	: C26H29N3O7
Mol.Wt.	: 495.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-N004024
CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004025
CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004026
CAS No	: NA
Mol.F.	: C33H34N4O9
Mol.Wt.	: 630.7
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004027
CAS No	: NA
Mol.F.	: C19H22N4O7
Mol.Wt.	: 418.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004028
CAS No	: NA
Mol.F.	: C26H32N4O7
Mol.Wt.	: 512.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004029
CAS No	: 2771193-14-5
Mol.F.	: C26H27N3O6 : C2H2O4
Mol.Wt.	: 477.5 : 90.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-N004030
CAS No	: NA
Mol.F.	: C25H26N4O7
Mol.Wt.	: 494.5
Inv. Status	: Custom Synthesis